Topical Application of Dipyridamole and Roflumilast Combination Nanoparticles Loaded Nanoemulgel for the Treatment of Psoriasis in Rats DOI Creative Commons

Zeyad Khalaf Maded,

Mohamed Ali Lassoued, Ghada A. Taqa

и другие.

International Journal of Nanomedicine, Год журнала: 2024, Номер Volume 19, С. 13113 - 13134

Опубликована: Дек. 1, 2024

Phosphodiesterase-4 is an enzyme that regulates immune responses and contributes to the development of psoriasis. Dipyridamole roflumilast function as phosphodiesterase-4 inhibitors, reducing pro-inflammatory cytokine expression. The aim was evaluate anti-psoriatic effect topical administration dipyridamole nanoemulgel combination on imiquimod-induced psoriasiform skin inflammation in rats.

Язык: Английский

Development of synergistic antifungal in situ gel of miconazole nitrate loaded microemulsion as a novel approach to treat vaginal candidiasis DOI Creative Commons

Omar Mohammed Alwan,

Iman Sabah Jaafar

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Окт. 5, 2024

Язык: Английский

Процитировано

3

Topical Application of Dipyridamole and Roflumilast Combination Nanoparticles Loaded Nanoemulgel for the Treatment of Psoriasis in Rats DOI Creative Commons

Zeyad Khalaf Maded,

Mohamed Ali Lassoued, Ghada A. Taqa

и другие.

International Journal of Nanomedicine, Год журнала: 2024, Номер Volume 19, С. 13113 - 13134

Опубликована: Дек. 1, 2024

Phosphodiesterase-4 is an enzyme that regulates immune responses and contributes to the development of psoriasis. Dipyridamole roflumilast function as phosphodiesterase-4 inhibitors, reducing pro-inflammatory cytokine expression. The aim was evaluate anti-psoriatic effect topical administration dipyridamole nanoemulgel combination on imiquimod-induced psoriasiform skin inflammation in rats.

Язык: Английский

Процитировано

1