Topical Application of Dipyridamole and Roflumilast Combination Nanoparticles Loaded Nanoemulgel for the Treatment of Psoriasis in Rats DOI Creative Commons

Zeyad Khalaf Maded,

Mohamed Ali Lassoued, Ghada A. Taqa

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 13113 - 13134

Published: Dec. 1, 2024

Phosphodiesterase-4 is an enzyme that regulates immune responses and contributes to the development of psoriasis. Dipyridamole roflumilast function as phosphodiesterase-4 inhibitors, reducing pro-inflammatory cytokine expression. The aim was evaluate anti-psoriatic effect topical administration dipyridamole nanoemulgel combination on imiquimod-induced psoriasiform skin inflammation in rats.

Language: Английский

Development of synergistic antifungal in situ gel of miconazole nitrate loaded microemulsion as a novel approach to treat vaginal candidiasis DOI Creative Commons

Omar Mohammed Alwan,

Iman Sabah Jaafar

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 5, 2024

Language: Английский

Citations

3
Topical Application of Dipyridamole and Roflumilast Combination Nanoparticles Loaded Nanoemulgel for the Treatment of Psoriasis in Rats DOI Creative Commons

Zeyad Khalaf Maded,

Mohamed Ali Lassoued, Ghada A. Taqa

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 13113 - 13134

Published: Dec. 1, 2024

Phosphodiesterase-4 is an enzyme that regulates immune responses and contributes to the development of psoriasis. Dipyridamole roflumilast function as phosphodiesterase-4 inhibitors, reducing pro-inflammatory cytokine expression. The aim was evaluate anti-psoriatic effect topical administration dipyridamole nanoemulgel combination on imiquimod-induced psoriasiform skin inflammation in rats.

Language: Английский

Citations

1