Diabetes & Metabolism Journal,
Год журнала:
2023,
Номер
47(1), С. 1 - 9
Опубликована: Янв. 27, 2023
Dyslipidemia
in
patients
with
diabetes
is
an
important
treatment
target
as
a
modifiable
risk
factor
for
cardiovascular
disease
(CVD).
Although
the
primary
goal
dyslipidemia
to
control
low-density
lipoprotein
cholesterol
(LDL-C),
achieving
this
remains
suboptimal
according
recent
studies.
It
set
LDL-C
based
on
accurate
assessment
CVD.
Here,
we
summarize
latest
evidence
lipid
management
and
present
consensus
of
Korean
Diabetes
Association
Society
Lipid
Atherosclerosis
goals
duration
diabetes,
presence
CVD,
organ
damage,
or
major
factors.
In
type
2
mellitus
(T2DM)
<55
mg/dL
reduction
level
by
50%
more
from
baseline
recommended.
For
prevention
CVD
T2DM
≥10
years,
factors,
<70
<10
years
no
<100
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Март 8, 2024
Abstract
The
clinical
utility
of
a
type
2
diabetes
mellitus
(T2DM)
polygenic
risk
score
(PRS)
in
the
East
Asian
population
remains
underexplored.
We
aimed
to
examine
potential
prognostic
value
T2DM
PRS
and
assess
its
viability
as
instrument.
first
established
for
5490
Korean
individuals
using
Biobank
data
(269,487
samples).
Subsequently,
we
assessed
predictive
capability
this
prospective
longitudinal
study
with
baseline
from
seven
additional
follow-ups.
Our
analysis
showed
that
could
predict
transition
glucose
tolerance
stages
normal
prediabetes
T2DM.
Moreover,
patients
top-decile
group
were
more
likely
be
treated
insulin
(hazard
ratio
=
1.69,
p
2.31E−02)
than
those
remaining
groups.
values
significantly
high
severe
subgroup,
characterized
by
resistance
$$\beta$$
β
-cell
dysfunction
(p
0.0012).
prediction
models
had
greater
Harrel’s
C-indices
did
corresponding
without
it.
By
utilizing
extensive
factor
information,
our
provides
valuable
insights
into
multifaceted
PRS.
Kidney Research and Clinical Practice,
Год журнала:
2024,
Номер
43(1), С. 20 - 32
Опубликована: Янв. 25, 2024
Korean
Renal
Data
System
(KORDS)
is
a
nationwide
end-stage
renal
disease
(ESRD)
registry
database
operated
by
the
Society
of
Nephrology
(KSN).
Diabetes
mellitus
currently
leading
cause
ESRD
in
Korea;
this
article
provides
an
update
on
trends
and
characteristics
diabetic
patients.
The
KORDS
Committee
KSN
collects
data
dialysis
centers
patients
through
online
program.
Here,
we
analyzed
status
chronic
kidney
stage
5D
(CKD
5D)
using
from
2001
to
2021.
In
2021,
adequacy
hemodialysis
(HD)
was
lower
CKD
than
nondiabetic
patients,
while
that
peritoneal
(PD)
similar.
Diabetic
had
higher
proportion
cardiac
vascular
diseases
were
more
frequently
admitted
hospitals
death
disease.
From
2020,
mortality
rate
but
2021
trend
reversed.
PD
highest
over
20
years.
HD
until
2019
became
starting
2020.
There
decreasing
still
prevalent
with
frequent
admissions
hospitals.
More
specialized
care
needed
improve
clinical
outcomes
Diabetes & Metabolism Journal,
Год журнала:
2025,
Номер
49(1), С. 13 - 21
Опубликована: Янв. 1, 2025
The
Korean
National
Health
Information
Database
(NHID),
which
contains
nationwide
real-world
claims
data
including
sociodemographic
data,
health
care
utilization
screening
and
healthcare
provider
information,
is
a
powerful
resource
to
test
various
hypotheses.
It
also
longitudinal
in
nature
due
the
recommended
checkup
every
2
years
appropriate
for
long-term
follow-up
study
as
well
evaluating
relationships
between
outcomes
changes
parameters
such
lifestyle
factors,
anthropometric
measurements,
laboratory
results.
However,
because
these
are
not
collected
research
purposes,
precise
operational
definitions
of
diseases
required
facilitate
big
analysis
using
NHID.
In
this
review,
we
describe
characteristics
NHID,
used
related
diabetes,
introduce
representative
diabetes-related
JAMA Network Open,
Год журнала:
2025,
Номер
8(1), С. e2455388 - e2455388
Опубликована: Янв. 21, 2025
Importance
There
is
limited
evidence
regarding
the
association
between
age
at
menopause
and
incident
type
2
diabetes
(T2D).
Objective
To
investigate
whether
premature
are
associated
with
T2D
incidence
in
postmenopausal
Korean
women.
Design,
Setting,
Participants
This
population-based
cohort
study
was
conducted
among
a
nationally
representative
sample
from
National
Health
Insurance
Service
database
of
1
125
378
women
without
who
enrolled
2009.
The
median
(IQR)
follow-up
8.4
(8.1-8.7)
years.
Data
were
analyzed
March
2024.
Exposures
Age
(menopause
onset
&lt;40
years).
Main
Outcomes
Measures
primary
outcome
T2D.
Multivariable
Cox
proportional
hazards
regression
analysis
used
to
estimate
hazard
ratios
(HRs)
95%
CIs
for
by
menopause,
adjusting
potential
confounders.
Results
Of
participants
(mean
[SD]
enrollment,
61.2
[8.4]
years),
113
864
individuals
(10.1%)
diagnosed
least
year
after
enrollment.
Women
ages
younger
than
40
years
(premature
menopause;
HR,
1.13;
CI,
1.08-1.18)
44
(HR,
1.03;
1.00-1.06)
had
increased
risk
compared
those
50
or
older,
adjustment
sociodemographic,
lifestyle,
cardiometabolic,
psychiatric,
reproductive
factors;
developing
(
P
trend
&lt;.001).
Body
mass
index,
depressive
disorder,
prediabetes
modified
subgroup
analyses;
example,
vs
HRs
1.54
(95%
1.14-2.06)
BMI
less
18.5
1.14
1.00-1.30)
30
greater
&lt;
.001),
1.28
1.12-1.45)
depression
1.11
1.07-1.16)
=
.01),
1.25
1.18-1.33)
not
prediabetic
1.04
0.99-1.11)
.001).
Conclusions
Relevance
In
this
study,
early
higher
T2D,
highlighting
need
targeted
public
health
strategies
aimed
preventing
delaying
Diabetes & Metabolism Journal,
Год журнала:
2022,
Номер
46(5), С. 667 - 674
Опубликована: Сен. 19, 2022
The
prevalence
of
diabetes
mellitus
continues
to
increase
worldwide,
and
it
is
a
well-established
cardiovascular
risk
factor.
Hypertension
also
an
important
factor
be
controlled
common
among
patients
with
mellitus.
Optimal
blood
pressure
(BP)
goals
have
been
the
subject
great
debate
in
management
hypertension
This
review
provides
detailed
results
from
randomized
trials
meta-analyses
clinical
outcomes
according
target
BP
type
2
In
addition,
recommended
by
different
guidelines
was
summarized
presented.
A
<140/90
mm
Hg
for
mellitus,
should
<130/80
who
high-risk
features.
We
hope
that
this
will
helpful
clinicians
promoting
understanding
appropriate
application
control
comprehensive
Diabetes & Metabolism Journal,
Год журнала:
2023,
Номер
47(5), С. 643 - 652
Опубликована: Авг. 7, 2023
We
evaluated
the
prevalence
and
management
of
diabetes
mellitus
(DM)
in
elderly
Korean
patients
based
on
data
from
Korea
National
Health
Nutrition
Examination
Survey
(KNHANES).
Journal of Lipid and Atherosclerosis,
Год журнала:
2023,
Номер
12(1), С. 12 - 12
Опубликована: Янв. 1, 2023
Dyslipidemia
in
patients
with
diabetes
is
an
important
treatment
target
as
a
modifiable
risk
factor
for
cardiovascular
disease
(CVD).
Although
the
primary
goal
dyslipidemia
to
control
low-density
lipoprotein
cholesterol
(LDL-C),
achieving
this
remains
suboptimal
according
recent
studies.
It
set
LDL-C
based
on
accurate
assessment
CVD.
Here,
we
summarize
latest
evidence
lipid
management
and
present
consensus
of
Korean
Diabetes
Association
Society
Lipid
Atherosclerosis
goals
duration
diabetes,
presence
CVD,
organ
damage,
or
major
factors.
In
type
2
mellitus
(T2DM)
<55
mg/dL
reduction
level
by
50%
more
from
baseline
recommended.
For
prevention
CVD
T2DM
≥10
years,
factors,
<70
<10
years
no
<100
Journal of Cachexia Sarcopenia and Muscle,
Год журнала:
2024,
Номер
15(2), С. 671 - 680
Опубликована: Янв. 14, 2024
Abstract
Background
The
risk
of
heart
failure
(HF)
in
underweight
diabetes
mellitus
(DM)
patients
has
rarely
been
studied.
We
conducted
a
cohort
study
to
investigate
the
association
between
(BMI
<
18.5
kg/m
2
)
and
BMI
change
over
time
HF
with
type
DM.
Methods
utilized
health
screening
data
from
National
Health
Insurance
Service
Korean
Screening
database
2009
2012,
follow‐up
until
December
2018.
Participants
DM
were
categorized
into
four
groups
based
on
their
at
4
years
before
inclusion
entry:
(1)
Always
Normal
Weight
ago/BMI
entry
≥18.5/≥18.5
,
reference
group);
(2)
Transitioned
Underweight
(≥18.5/<18.5
);
(3)
(<18.5/≥18.5
(4)
(<18.5/<18.5
).
followed
development
or
end
follow‐up.
Initial
included
participants
who
had
during
period
(
n
=
2,746,079).
aged
<20
390),
those
did
not
undergo
examination
prior
1,306,520),
missing
77,410)
excluded.
diagnosed
participation
81,645)
within
1
year
enrolment
11,731)
After
applying
exclusion
criteria,
1,268,383
finally
analysis.
primary
outcome
was
HF.
employed
Cox
proportional
hazards
models,
adjusting
for
various
confounding
factors,
assess
developing
Results
Median
duration
6.88
men
63.16%.
mean
ages
each
as
follows:
(57.92
±
11.64
years),
(62
13.5
(56.6
15.29
years)
(57.76
15.35
years).
In
comparison
group
1,245,381,
76,360),
9304,
880,
adjusted
Hazard
Ratio
(aHR)1.389,
95%
confidence
interval
(CI)
1.3–1.485)
6024,
478,
aHR
1.385,
CI
1.266–1.515)
exhibited
an
increased
highest
observed
7674,
665,
1.612,
1.493–1.740).
Conclusions
significantly
associated
population.
Active
surveillance
population
is
needed.
Respirology,
Год журнала:
2024,
Номер
29(7), С. 624 - 632
Опубликована: Март 27, 2024
Patients
with
tuberculosis
and
diabetes
have
a
higher
risk
of
unfavourable
anti-tuberculosis
treatment
outcomes.
In
the
present
study,
we
aimed
to
evaluate
effects
various
statuses
on
outcomes
patients
pulmonary
tuberculosis.
