Diabetes & Metabolism Journal,
Journal Year:
2023,
Volume and Issue:
47(2), P. 201 - 210
Published: Feb. 8, 2023
Background:
We
evaluated
the
validity
and
reliability
of
operational
definition
type
2
diabetes
mellitus
(T2DM)
based
on
Korean
National
Health
Insurance
Service
(NHIS)
database.Methods:
Adult
subjects
(≥40
years
old)
included
in
Korea
Nutrition
Examination
Survey
(KNHANES)
from
2008
to
2017
were
merged
with
those
NHIS
health
check-up
database,
producing
a
cross-sectional
dataset.
sensitivity,
specificity,
accuracy,
agreement
criteria
for
defining
T2DM
by
comparing
them
KNHANES
as
standard
reference.Results:
In
study
population
(n=13,006),
two
algorithms
devised
determine
dataset
whether
diagnostic
claim
codes
accompanied
prescription
anti-diabetic
drugs
(algorithm
1)
or
not
2).
Using
these
algorithms,
prevalence
was
14.9%
(n=1,942;
algorithm
20.8%
(n=2,707;
Good
observed
both
(Kappa
index,
0.73
[algorithm
1],
0.63
2]).
However,
accuracy
(0.93
vs.
0.89)
specificity
(0.96
0.90)
tended
be
higher
1
than
2.
The
(accuracy,
ranging
0.91
0.95)
0.68
0.78)
independent
age,
sex,
socioeconomic
status,
hypertension
dyslipidemia.Conclusion:
population-based
claims
data,
including
codes,
could
valid
tool
identify
individuals
population.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: March 8, 2024
Abstract
The
clinical
utility
of
a
type
2
diabetes
mellitus
(T2DM)
polygenic
risk
score
(PRS)
in
the
East
Asian
population
remains
underexplored.
We
aimed
to
examine
potential
prognostic
value
T2DM
PRS
and
assess
its
viability
as
instrument.
first
established
for
5490
Korean
individuals
using
Biobank
data
(269,487
samples).
Subsequently,
we
assessed
predictive
capability
this
prospective
longitudinal
study
with
baseline
from
seven
additional
follow-ups.
Our
analysis
showed
that
could
predict
transition
glucose
tolerance
stages
normal
prediabetes
T2DM.
Moreover,
patients
top-decile
group
were
more
likely
be
treated
insulin
(hazard
ratio
=
1.69,
p
2.31E−02)
than
those
remaining
groups.
values
significantly
high
severe
subgroup,
characterized
by
resistance
$$\beta$$
β
-cell
dysfunction
(p
0.0012).
prediction
models
had
greater
Harrel’s
C-indices
did
corresponding
without
it.
By
utilizing
extensive
factor
information,
our
provides
valuable
insights
into
multifaceted
PRS.
Kidney Research and Clinical Practice,
Journal Year:
2024,
Volume and Issue:
43(1), P. 20 - 32
Published: Jan. 25, 2024
Korean
Renal
Data
System
(KORDS)
is
a
nationwide
end-stage
renal
disease
(ESRD)
registry
database
operated
by
the
Society
of
Nephrology
(KSN).
Diabetes
mellitus
currently
leading
cause
ESRD
in
Korea;
this
article
provides
an
update
on
trends
and
characteristics
diabetic
patients.
The
KORDS
Committee
KSN
collects
data
dialysis
centers
patients
through
online
program.
Here,
we
analyzed
status
chronic
kidney
stage
5D
(CKD
5D)
using
from
2001
to
2021.
In
2021,
adequacy
hemodialysis
(HD)
was
lower
CKD
than
nondiabetic
patients,
while
that
peritoneal
(PD)
similar.
Diabetic
had
higher
proportion
cardiac
vascular
diseases
were
more
frequently
admitted
hospitals
death
disease.
From
2020,
mortality
rate
but
2021
trend
reversed.
PD
highest
over
20
years.
HD
until
2019
became
starting
2020.
There
decreasing
still
prevalent
with
frequent
admissions
hospitals.
More
specialized
care
needed
improve
clinical
outcomes
JMIR Public Health and Surveillance,
Journal Year:
2024,
Volume and Issue:
10, P. e59571 - e59571
Published: Aug. 27, 2024
Background
Type
2
diabetes
poses
an
increasing
disease
burden
in
South
Korea.
The
development
and
management
of
type
are
closely
related
to
lifestyle
socioeconomic
factors,
which
have
undergone
substantial
changes
over
the
past
few
decades,
including
during
COVID-19
pandemic.
Objective
This
study
aimed
investigate
long-term
trends
prevalence,
awareness,
treatment,
control.
It
also
determine
whether
there
were
alterations
pandemic
these
more
pronounced
within
specific
demographic
groups.
Methods
examined
control
a
representative
sample
139,786
Koreans
aged
>30
years,
using
data
from
National
Health
Nutrition
Examination
Survey
covering
period
1998
2022.
Weighted
linear
regression
binary
logistic
performed
calculate
weighted
β
coefficients
or
odds
ratios.
Stratified
analyses
based
on
sex,
age,
region
residence,
obesity
status,
educational
background,
household
income,
smoking
status.
(difference)
was
calculated
analyze
trend
difference
between
prepandemic
To
identify
groups
susceptible
diabetes,
we
estimated
interaction
terms
for
each
factor
Results
From
2022,
consistent
increase
prevalence
observed
among
Koreans,
with
notable
rise
15.61%
(95%
CI
14.83-16.38)
Awareness
followed
U-shaped
curve,
bottoming
out
at
64.37%
61.79-66.96)
2013
2015
before
72.56%
70.39-74.72)
Treatment
increased
time,
peaking
68.33%
65.95-70.71)
Control
participants
showed
no
change,
maintaining
rate
29.14%
26.82-31.47)
2020
while
treated
improved
30.68%
27.88-33.48).
During
pandemic,
steepening
curves
awareness
treatment.
However,
slope
being
increased,
change
Older
populations
individuals
lower
level
exhibited
less
improvement
than
younger
educated
individuals.
People
income
experienced
deceleration
Conclusions
Over
recent
decade,
has
been
steeper
observed.
heterogeneous
across
different
population
groups,
underscoring
need
targeted
interventions
address
disparities
improve
populations.
Diabetes & Metabolism Journal,
Journal Year:
2022,
Volume and Issue:
46(5), P. 667 - 674
Published: Sept. 19, 2022
The
prevalence
of
diabetes
mellitus
continues
to
increase
worldwide,
and
it
is
a
well-established
cardiovascular
risk
factor.
Hypertension
also
an
important
factor
be
controlled
common
among
patients
with
mellitus.
Optimal
blood
pressure
(BP)
goals
have
been
the
subject
great
debate
in
management
hypertension
This
review
provides
detailed
results
from
randomized
trials
meta-analyses
clinical
outcomes
according
target
BP
type
2
In
addition,
recommended
by
different
guidelines
was
summarized
presented.
A
<140/90
mm
Hg
for
mellitus,
should
<130/80
who
high-risk
features.
We
hope
that
this
will
helpful
clinicians
promoting
understanding
appropriate
application
control
comprehensive
PLoS ONE,
Journal Year:
2022,
Volume and Issue:
17(6), P. e0268290 - e0268290
Published: June 16, 2022
Objective
Prevention
of
tuberculosis
(TB)
recurrence
is
an
important
issue
in
TB
control.
South
Korea,
a
country
with
high
average
income,
has
been
challenged
intermediate
burden
TB.
We
aimed
to
estimate
the
rate
after
successful
completion
first
anti-TB
chemotherapy,
and
identify
risk
factors
for
by
focusing
on
co-morbidities
behavioral
factors.
Methods
This
population-based
cohort
study
using
data
from
National
Health
Insurance
(NHI)
database
between
2002
2013.
Newly
diagnosed
patients
were
identified
classification
disease
codes
prescription
records.
Final
analytical
subjects
included
people
who
successfully
completed
chemotherapy.
The
primary
outcome
measure
was
recurrent
6-month
treatment
completion.
A
set
associated
factors,
including
demographic
characteristics,
co-morbidities,
health
behavior
analyzed
Cox
regression
analysis.
Results
Among
5,446
patients,
2,226
(40.1%)
treatment.
During
follow-up
period,
150
(6.7%)
had
recurrence,
crude
22.6
per
1000
person-years.
majority
cases
(89%)
occurred
within
2-year
period.
major
findings
show
that
participants
are
male
(adjusted
HR
(aHR)
=
1.81,
at
95%
CI,
range:
1.11–2.94),
older
age
(aHR
1.07,
1.00–1.14),
have
lower
income
1.96,
1.10–3.48)
underweight
1.92,
range
1.15–3.20)
higher
risks
recurrence.
Conclusion
People
need
improve
compliance
through
more
effective
management,
observation
one
or
two
years
Journal of Lipid and Atherosclerosis,
Journal Year:
2023,
Volume and Issue:
12(1), P. 12 - 12
Published: Jan. 1, 2023
Dyslipidemia
in
patients
with
diabetes
is
an
important
treatment
target
as
a
modifiable
risk
factor
for
cardiovascular
disease
(CVD).
Although
the
primary
goal
dyslipidemia
to
control
low-density
lipoprotein
cholesterol
(LDL-C),
achieving
this
remains
suboptimal
according
recent
studies.
It
set
LDL-C
based
on
accurate
assessment
CVD.
Here,
we
summarize
latest
evidence
lipid
management
and
present
consensus
of
Korean
Diabetes
Association
Society
Lipid
Atherosclerosis
goals
duration
diabetes,
presence
CVD,
organ
damage,
or
major
factors.
In
type
2
mellitus
(T2DM)
<55
mg/dL
reduction
level
by
50%
more
from
baseline
recommended.
For
prevention
CVD
T2DM
≥10
years,
factors,
<70
<10
years
no
<100
Diabetes & Metabolism Journal,
Journal Year:
2023,
Volume and Issue:
47(5), P. 643 - 652
Published: Aug. 7, 2023
We
evaluated
the
prevalence
and
management
of
diabetes
mellitus
(DM)
in
elderly
Korean
patients
based
on
data
from
Korea
National
Health
Nutrition
Examination
Survey
(KNHANES).
Diabetes & Metabolism Journal,
Journal Year:
2023,
Volume and Issue:
47(1), P. 1 - 9
Published: Jan. 27, 2023
Dyslipidemia
in
patients
with
diabetes
is
an
important
treatment
target
as
a
modifiable
risk
factor
for
cardiovascular
disease
(CVD).
Although
the
primary
goal
dyslipidemia
to
control
low-density
lipoprotein
cholesterol
(LDL-C),
achieving
this
remains
suboptimal
according
recent
studies.
It
set
LDL-C
based
on
accurate
assessment
CVD.
Here,
we
summarize
latest
evidence
lipid
management
and
present
consensus
of
Korean
Diabetes
Association
Society
Lipid
Atherosclerosis
goals
duration
diabetes,
presence
CVD,
organ
damage,
or
major
factors.
In
type
2
mellitus
(T2DM)
<55
mg/dL
reduction
level
by
50%
more
from
baseline
recommended.
For
prevention
CVD
T2DM
≥10
years,
factors,
<70
<10
years
no
<100
