Clinical Nutrition, Год журнала: 2024, Номер 43(10), С. 2388 - 2389
Опубликована: Сен. 6, 2024
Язык: Английский
Clinical Nutrition, Год журнала: 2024, Номер 43(7), С. 1675 - 1682
Опубликована: Май 23, 2024
This study aimed to investigate the potential association between dietary live microbe intake and sarcopenia.
Язык: Английский
Процитировано
18
Emergency Medicine Australasia, Год журнала: 2025, Номер 37(1)
Опубликована: Фев. 1, 2025
Abstract Objective To explore whether utilisation of a Virtual Emergency Department (VVED) differs according to socioeconomic status (SES). Methods A retrospective analysis was undertaken data from the VVED – telehealth service that provides care for patients across Victoria, Australia with non‐life‐threatening emergencies. The study included all individuals who presented between July 2022 and June 2023 through two most common referral pathways (self‐referral ambulance referral). Area‐level SES ascertained by matching residential postcodes corresponding Australian Bureau Statistics (ABS) Index Relative Socioeconomic Advantage Disadvantage (IRSAD) decile. IRSAD scores were divided into quintiles (1 = lowest SES, 5 highest SES) multivariable logistic regression modelling used analyse associations quintile pathway, as odds ratios (ORs) 95% confidence intervals (CIs). Results There 68 598 participants in analyses (mean age: 36.6 years; 58.4% female). Compared 3, higher self‐referral observed advantaged groups (Quintile 4; adjusted OR [aOR] 1.16; CI: 1.06–1.26; P 0.001) 5; aOR 1.38; 1.25–1.52; < 0.001). Conversely, lower disadvantaged group 1; 0.82; 0.75–0.90; Conclusions present demonstrated relatively even population groups. use healthcare provider pathways, such paramedics, may increase equitable access telehealth. Clinical attention should be directed toward specific social emergency setting.
Язык: Английский
Процитировано
1
Frontiers in Endocrinology, Год журнала: 2025, Номер 15
Опубликована: Янв. 8, 2025
This study aimed to investigate the alterations in diabetes risk associated with sarcopenia and insufficient physical activity, as well demographic shifts within diabetic population. Utilizing pertinent data from National Health Nutrition Examination Survey (NHANES) database spanning 2011 2018, criteria for were established by Foundation Institutes of Health. These calculated using lean body mass conjunction index data. Physical activity levels assessed PAQ questionnaire NHANES database. The presence was determined through DIQ laboratory examination analysis performed multivariable logistic regression. prevalence both population 188% greater than non-diabetic Sarcopenia positively correlated an increased onset, demonstrating a 1.45-fold heightened when conditions present (OR=2.45,95%CI,1.35-4.44,P<0.05). combined effect significantly alone (OR=1.84,95%CI,1.09-3.11,P<0.05) or (OR=1.55,95%CI,1.11-2.15,P<0.05). A synergistic relationship exists between resulting markedly elevated are concurrently. Therefore, comprehensive management strategies should prioritize populations exhibiting activity.
Язык: Английский
Процитировано
0
Experimental Neurology, Год журнала: 2025, Номер 385, С. 115137 - 115137
Опубликована: Янв. 10, 2025
Язык: Английский
Процитировано
0
Salud Ciencia y Tecnología, Год журнала: 2025, Номер 4
Опубликована: Янв. 15, 2025
Introduction. Type 2 diabetes mellitus (T2DM) is a metabolic disease characterized by elevated glucose levels, which over time can cause severe vascular complications such as retinopathy, neuropathy, nephropathy, and cerebrovascular accident (CVA). Body composition, particularly lean mass, fat-free skeletal muscle mass key factor in preventing these complications. This study evaluated the relationship between body measured bioimpedance, T2DM patients. Methods. A quantitative, correlational, multivariate was conducted with 88 patients aged 18 to 90 years from clubs province of Tungurahua. Bioimpedance (Inbody S10) used measure composition. Data were analyzed using descriptive statistics, Pearson correlation, principal component analysis SPSS.Results. The results showed that decreased significantly age, correlates higher risk Skeletal had weaker correlation complications, especially case retinopathy. Microvascular neuropathy more related mass. Conclusions. Preserving are critical factors for reducing Physical exercise proper nutrition suggested maintain healthy older adults, strategy prevent microvascular macrovascular
Язык: Английский
Процитировано
0
IntechOpen eBooks, Год журнала: 2025, Номер unknown
Опубликована: Фев. 19, 2025
Sarcopenia refers to the rapid loss of skeletal muscle mass and strength, which can result in serious consequences such as falls, fractures, a higher risk mortality. The prevalence sarcopenia is observed be twice high individuals with type 2 diabetes mellitus. Notably, there bidirectional relationship between mellitus, where each condit‑‑ion exacerbate progression other. Overlapping pathophysiological mechanisms, insulin resistance, inflammation, oxidative stress, accumulation advanced glycation end products, mitochondrial dysfunction, myosteatosis, aging process itself contribute development both conditions. A few treatments, myostatin antagonists, testosterone supplementation, selective androgen receptor modulators have been explored, but many remain experimental or clinical trial stages. cornerstone management involves nutritional intervention foods rich protein, essential amino acids, vitamin D, omega-3 fatty acids. Additionally, incorporating regular physical activity, particularly resistance exercises, minimizing sedentary behavior are key components for sarcopenia.
Язык: Английский
Процитировано
0
Archives of Gerontology and Geriatrics, Год журнала: 2025, Номер 133, С. 105807 - 105807
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
Frontiers in Public Health, Год журнала: 2025, Номер 13
Опубликована: Апрель 3, 2025
People with diabetes mellitus (DM) have a significantly increased risk of sarcopenia. A cross-sectional analysis was performed using nationally representative data to evaluate possible sarcopenia in middle-aged and older adults mellitus, develop validate prediction model suitable for the Chinese community. Data from China Health Retirement Longitudinal Study (CHARLS), which focuses on people 45 years age or older, served as basis model. CHARLS 2015 participants were used study, examined 53 factors. In order guarantee reliability, study split into two groups at random: 70% training 30% validation. Ten-fold cross-validation Least Absolute Shrinkage Selection Operator (LASSO) regression analyses determine best predictors The factors associated DM researched logistic models. Nomogram constructed predictive performance assessed area under curve (AUC), calibration curves decision (DCA). total 2,131 database collected passed final analysis, prevalence 28.9% (616/2131). Eight subsequently chosen models by LASSO regression: age, residence, body mass index, diastolic blood pressure, cognitive function, activities daily living, peak expiratory flow hemoglobin. These nomogram model, showed good accuracy agreement. AUC values validation sets 0.867 (95%CI: 0.847~0.887) 0.849 0.816~0.883). Calibration DCA indicated that exhibited performance. this can be probability adult DM, is helpful early identification intervention high-risk groups.
Язык: Английский
Процитировано
0
Life, Год журнала: 2025, Номер 15(4), С. 677 - 677
Опубликована: Апрель 21, 2025
Background: Apart from classical elements in primary hyperparathyroidism (PHPT), non-classical complications, including type 2 diabetes mellitus (T2DM), are reported some patients, but currently, they do not represent a parathyroidectomy (PTx) indication. Objective: to explore the latest data regarding glucose profile, particularly, T2DM and metabolic syndrome (MetS) PHPT, post-PTx. Methods: PubMed-based review included English-published original studies between January 2020 December 2024 (n = 20). Results: Studied population: 764,485 subjects (female-to-male ratio of 1.26:1; 23,931 were PHPT patients vs. 740,502 controls). prevalence 13; N 763,645 patients; 55.92% females): 4–60% (higher controls); for largest study (N 699,157) 31.3%. Age-based analysis: higher at >50 <50 years (14.4% 2.6%, p < 0.001), all agreed. Concurrent vitamin D deficiency as contributor risk had limited evidence. The association MetS-PHPT 2) no clear conclusion. Post-PTx showed following: lower glycaemia, fasting insulin, insulin resistance (HOMA-IR) improvement, reduced rate (but agreed). with prediabetes might population sub-group highest post-PTx benefit. Conclusions: panel PHPT-T2DM interplay remains heterogeneous. Data improvement disorders still conflicting, recent findings suggested that surgery has beneficial effects, especially confirmed pre-existing prediabetes. Patients normocalcemic variant seemed be less affected by glucose-related disturbances, further needed. A better understanding intricate relationship metabolism anomalies will help providing optimal management reduce overall disease burden.
Язык: Английский
Процитировано
0
BMC Geriatrics, Год журнала: 2025, Номер 25(1)
Опубликована: Май 16, 2025
Type 2 Diabetes Mellitus (T2DM) is closely linked with sarcopenia. The lack of validated, easy, and effective sarcopenia screening tools for people T2DM may result in underdiagnosis, delayed interventions, worsening outcomes. This study evaluated compared the diagnostic accuracy various outpatients. A cross-sectional was conducted on 329 at Phramongkutklao Hospital, Thailand, between December 2023 November 2024. eight tools. Asian Working Group Sarcopenia 2019 (AWGS 2019) criteria served as reference standard. Sensitivity, Specificity, were using receiver operating characteristic (ROC) curve analysis. optimal cutoffs identified Youden index. prevalence 23.7%. Calf circumference showed highest standard cutoff (AUC: 0.892), optimised points < 37.0 cm males 36.0 females, achieved high sensitivity (90.1% males, 91.1% females) acceptable specificity (77.2% 67.8% females). Neck demonstrated utility 0.741) proposed thresholds 39.5 (males) 36.5 (females), yielding moderate (69.7% 82.2% (78.9% 62.6% Questionnaire-based limited SARC-CalF performing best 0.789, sensitivity: 48.7%, specificity: 93.2%). Among physical performance tests, handgrip strength most accurate 0.716), although these tests generally exhibited sensitivity, but lower specificity. tool T2DM. emerged a promising alternative values, offering simple, novel practice option. These findings support implementation anthropometric measures clinical settings, particularly outpatient care.
Язык: Английский
Процитировано
0