Molecular Profiles of Sensitization to Non-Specific Lipid Transfer Proteins in Lithuania: Single Center Experience DOI Open Access
Sandra Sakalauskaitė,

Ligita Pilkyte,

Edita Gasiūnienė

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(24), С. 13535 - 13535

Опубликована: Дек. 18, 2024

Non-specific Lipid Transfer proteins (nsLTPs) are relevant allergens of several pollens and plant foods. Sensitization to nsLTPs is not typical in our region. Still, it has become an increasingly common cause IgE-mediated food allergies food-induced anaphylaxis Northern Europe recent decades. No in-depth studies describe the prevalence sensitization molecular components Lithuania. This study aimed determine profile atopic patients at Immunology Allergy Department Kauno Klinikos nsLTPs, using allergen component analysis. Sixty Lithuanian adults with symptoms allergic rhinitis and/or asthma were included into study. Specific immunoglobulin E (IgE) levels measured two vitro techniques: extract Results showed that 25% subjects sensitized nsLTP-containing sources, mostly Zea m 14, Mal d 3, Vit v 1, Art 3. The median amount total IgE was higher nsLTP-sensitized than nsLTP-nonsensitized patients. Based on Cohen’s Kappa McNemar tests, results analysis tests do always agree, especially when we sources containing nsLTPs. Molecular could be first choice determining detailed who experienced unknown origin.

Язык: Английский

Evolution Toward Chip-Based Arrays in the Laboratory Diagnosis of Human Allergic Disease DOI Open Access

Robert G. Hamilton,

Derek Croote, Christian Lupinek

и другие.

The Journal of Allergy and Clinical Immunology In Practice, Год журнала: 2023, Номер 11(10), С. 2991 - 2999

Опубликована: Авг. 18, 2023

Язык: Английский

Процитировано

8
Molecular Profiles of Sensitization to Non-Specific Lipid Transfer Proteins in Lithuania: Single Center Experience DOI Open Access
Sandra Sakalauskaitė,

Ligita Pilkyte,

Edita Gasiūnienė

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(24), С. 13535 - 13535

Опубликована: Дек. 18, 2024

Non-specific Lipid Transfer proteins (nsLTPs) are relevant allergens of several pollens and plant foods. Sensitization to nsLTPs is not typical in our region. Still, it has become an increasingly common cause IgE-mediated food allergies food-induced anaphylaxis Northern Europe recent decades. No in-depth studies describe the prevalence sensitization molecular components Lithuania. This study aimed determine profile atopic patients at Immunology Allergy Department Kauno Klinikos nsLTPs, using allergen component analysis. Sixty Lithuanian adults with symptoms allergic rhinitis and/or asthma were included into study. Specific immunoglobulin E (IgE) levels measured two vitro techniques: extract Results showed that 25% subjects sensitized nsLTP-containing sources, mostly Zea m 14, Mal d 3, Vit v 1, Art 3. The median amount total IgE was higher nsLTP-sensitized than nsLTP-nonsensitized patients. Based on Cohen’s Kappa McNemar tests, results analysis tests do always agree, especially when we sources containing nsLTPs. Molecular could be first choice determining detailed who experienced unknown origin.

Язык: Английский

Процитировано

0