Application of Nanobiosensor Engineering in the Diagnosis of Neurodegenerative Disorders
Results in Engineering,
Год журнала:
2024,
Номер
24, С. 102790 - 102790
Опубликована: Сен. 5, 2024
Язык: Английский
Nanotools for Screening Neurodegenerative Diseases
Опубликована: Янв. 1, 2023
This
paper
underlines
the
critical
need
for
novel
diagnostic
techniques
against
increasing
worldwide
burden
of
neurodegenerative
disorders
(NDDs).
The
intricacies
Alzheimer's,
Parkinson's,
and
Huntington's
necessitate
very
accurate
sensitive
early
detection
strategies.
In
addition,
it
provides
an
essential
look
at
promise
role
nanotechnology
potential
nanoscale
material
technology
integration
to
revolutionize
preclinical
disease
diagnostics.
Furthermore,
allows
pinpoint
identification
biomarkers
pathological
alterations.
We
discussed
different
types
nanotools,
including
nanoparticles,
nanosensors,
imaging
agents,
nanomedicine.
process
metamorphosis,
however,
has
its
challenges.
development
these
cutting-edge
instruments
necessitates
careful
thought
on
issues
ethics,
safety,
biocompatibility.
Despite
limitations,
nanotools'
importance
in
changing
course
screening
is
undeniable.
Язык: Английский
Nanobiosensors in neurodegenerative disease diagnosis: A promising pathway for early detection
Digital Health,
Год журнала:
2025,
Номер
11
Опубликована: Май 1, 2025
Neurodegenerative
diseases,
including
Alzheimer's
and
Parkinson's,
are
characterized
by
progressive
neuronal
loss,
leading
to
cognitive
motor
impairments.
Early
diagnosis
remains
a
challenge
due
the
slow
progression
of
symptoms
limitations
current
diagnostic
methods.
Nanobiosensors,
leveraging
high
sensitivity
specificity
nanotechnology,
offer
promising,
noninvasive,
cost-effective
approach
for
detecting
disease
biomarkers
at
ultra-low
concentrations.
This
review
highlights
recent
advancements
in
nanobiosensor
technology,
integration
gold
nanoparticles,
quantum
dots,
carbon
nanotubes,
which
have
significantly
enhanced
biomarker
detection
precision.
Furthermore,
it
examines
advantages
nanobiosensors
over
traditional
techniques,
such
as
improved
sensitivity,
rapid
detection,
minimal
invasiveness.
The
potential
these
innovative
sensors
revolutionize
early
improve
patient
outcomes
is
discussed,
along
with
existing
challenges
clinical
translation,
stability,
reproducibility,
regulatory
considerations.
Addressing
will
be
crucial
integrating
into
routine
practice
advancing
personalized
medicine
neurodegenerative
disorders.
Язык: Английский
Graphene‐Based Enzymatic and Non‐Enzymatic Electrochemical Glucose Sensors: Review of Current Research and Advances in Nanotechnology
ChemistrySelect,
Год журнала:
2023,
Номер
8(46)
Опубликована: Дек. 10, 2023
Abstract
The
determination
of
the
body's
glucose
level
is
a
difficult
job
that
has
served
as
foundation
for
substantial
research
efforts
in
biosensing
applications.
Recent
advances
material
engineering
and
synthesis
methodologies
have
had
significant
influence
on
development
enzymatic
non‐enzymatic
sensors
detection
may
be
used
managing
diabetes,
food
technology,
clinical,
bio‐processing
intricate
fabrication,
detecting
principles
phenomena
involved,
alterations,
design
to
improve
sensor
performance.
There
great
need
high‐efficiency,
low‐cost
blood
industrial
domestic
scales.
This
review
primarily
intended
shed
light
current
state
knowledge
about
use
graphene.
performance
comprehensively
compared
with
electrochemical
based
study
will
go
over
been
conducted
build
biosensors
employing
nanostructures
such
carbon
nanotubes,
graphene,
metal
nanoparticles,
oxides,
sulfides.
manufacturing
very
sensitive
enzyme‐free
biosensor
thoroughly
discussed.
A
thorough
examination
graphene
co‐catalyst
sensitivity
also
provided.
Язык: Английский
AChE inhibitory effect, anti-oxidant and anti-inflammatory properties of cyclen and L-Dopa related compounds: Targeting in neurodegenerative disease
Journal of Molecular Structure,
Год журнала:
2023,
Номер
1287, С. 135665 - 135665
Опубликована: Апрель 25, 2023
Язык: Английский
Choline chloride based eutectic solvent: a highly efficient reaction media for the synthesis of 3,4-dihydropyrimidin-2(1H)-thiones
Journal of Composites and Compounds,
Год журнала:
2022,
Номер
4(12), С. 153 - 157
Опубликована: Сен. 30, 2022
A
mild
and
green
protocol
was
developed
to
the
3,4-dihydropyrimidin-2(1H)-thione
derivatives
preparation
in
deep
eutectic
solvent
without
use
of
a
catalyst
or
any
other
additive.
The
procedure
offers
number
benefits,
including
clean
reaction
profile,
avoiding
typical
toxic
catalysts,
an
easy
workup
procedure,
short
times,
low
prices.
Язык: Английский