Choline chloride based eutectic solvent: a highly efficient reaction media for the synthesis of 3,4-dihydropyrimidin-2(1H)-thiones DOI Open Access
Fatemeh Malamiri, Rashid Badri, Samad Khaksar

и другие.

Journal of Composites and Compounds, Год журнала: 2022, Номер 4(12), С. 153 - 157

Опубликована: Сен. 30, 2022

A mild and green protocol was developed to the 3,4-dihydropyrimidin-2(1H)-thione derivatives preparation in deep eutectic solvent without use of a catalyst or any other additive. The procedure offers number benefits, including clean reaction profile, avoiding typical toxic catalysts, an easy workup procedure, short times, low prices.

Язык: Английский

Application of Nanobiosensor Engineering in the Diagnosis of Neurodegenerative Disorders DOI Creative Commons

Thikra S. Dhahi,

Alaa Kamal Yousif Dafhalla, A. Wesam Al-Mufti

и другие.

Results in Engineering, Год журнала: 2024, Номер 24, С. 102790 - 102790

Опубликована: Сен. 5, 2024

Язык: Английский

Процитировано

12

Nanotools for Screening Neurodegenerative Diseases DOI
Bakr Ahmed Taha, Mohd Hadri Hafiz Mokhtar, Retna Apsari

и другие.

Опубликована: Янв. 1, 2023

This paper underlines the critical need for novel diagnostic techniques against increasing worldwide burden of neurodegenerative disorders (NDDs). The intricacies Alzheimer's, Parkinson's, and Huntington's necessitate very accurate sensitive early detection strategies. In addition, it provides an essential look at promise role nanotechnology potential nanoscale material technology integration to revolutionize preclinical disease diagnostics. Furthermore, allows pinpoint identification biomarkers pathological alterations. We discussed different types nanotools, including nanoparticles, nanosensors, imaging agents, nanomedicine. process metamorphosis, however, has its challenges. development these cutting-edge instruments necessitates careful thought on issues ethics, safety, biocompatibility. Despite limitations, nanotools' importance in changing course screening is undeniable.

Язык: Английский

Процитировано

10

Nanobiosensors in neurodegenerative disease diagnosis: A promising pathway for early detection DOI Creative Commons
Shikha Yadav, Sarad Pawar Naik Bukke,

Shatrudhan Prajapati

и другие.

Digital Health, Год журнала: 2025, Номер 11

Опубликована: Май 1, 2025

Neurodegenerative diseases, including Alzheimer's and Parkinson's, are characterized by progressive neuronal loss, leading to cognitive motor impairments. Early diagnosis remains a challenge due the slow progression of symptoms limitations current diagnostic methods. Nanobiosensors, leveraging high sensitivity specificity nanotechnology, offer promising, noninvasive, cost-effective approach for detecting disease biomarkers at ultra-low concentrations. This review highlights recent advancements in nanobiosensor technology, integration gold nanoparticles, quantum dots, carbon nanotubes, which have significantly enhanced biomarker detection precision. Furthermore, it examines advantages nanobiosensors over traditional techniques, such as improved sensitivity, rapid detection, minimal invasiveness. The potential these innovative sensors revolutionize early improve patient outcomes is discussed, along with existing challenges clinical translation, stability, reproducibility, regulatory considerations. Addressing will be crucial integrating into routine practice advancing personalized medicine neurodegenerative disorders.

Язык: Английский

Процитировано

0

Graphene‐Based Enzymatic and Non‐Enzymatic Electrochemical Glucose Sensors: Review of Current Research and Advances in Nanotechnology DOI

Qurat-ul-Ain Qurat-ul-Ain,

RanaRashad Mahmood Khan,

Muhammad Pervaiz

и другие.

ChemistrySelect, Год журнала: 2023, Номер 8(46)

Опубликована: Дек. 10, 2023

Abstract The determination of the body's glucose level is a difficult job that has served as foundation for substantial research efforts in biosensing applications. Recent advances material engineering and synthesis methodologies have had significant influence on development enzymatic non‐enzymatic sensors detection may be used managing diabetes, food technology, clinical, bio‐processing intricate fabrication, detecting principles phenomena involved, alterations, design to improve sensor performance. There great need high‐efficiency, low‐cost blood industrial domestic scales. This review primarily intended shed light current state knowledge about use graphene. performance comprehensively compared with electrochemical based study will go over been conducted build biosensors employing nanostructures such carbon nanotubes, graphene, metal nanoparticles, oxides, sulfides. manufacturing very sensitive enzyme‐free biosensor thoroughly discussed. A thorough examination graphene co‐catalyst sensitivity also provided.

Язык: Английский

Процитировано

6

AChE inhibitory effect, anti-oxidant and anti-inflammatory properties of cyclen and L-Dopa related compounds: Targeting in neurodegenerative disease DOI
Lili Arabuli, Petra Lovecká,

Rudolf Ježek

и другие.

Journal of Molecular Structure, Год журнала: 2023, Номер 1287, С. 135665 - 135665

Опубликована: Апрель 25, 2023

Язык: Английский

Процитировано

4

Choline chloride based eutectic solvent: a highly efficient reaction media for the synthesis of 3,4-dihydropyrimidin-2(1H)-thiones DOI Open Access
Fatemeh Malamiri, Rashid Badri, Samad Khaksar

и другие.

Journal of Composites and Compounds, Год журнала: 2022, Номер 4(12), С. 153 - 157

Опубликована: Сен. 30, 2022

A mild and green protocol was developed to the 3,4-dihydropyrimidin-2(1H)-thione derivatives preparation in deep eutectic solvent without use of a catalyst or any other additive. The procedure offers number benefits, including clean reaction profile, avoiding typical toxic catalysts, an easy workup procedure, short times, low prices.

Язык: Английский

Процитировано

0