The Association of Prolactin and CRP Biomarkers with the Severity of COVID-19 in Thumpay Hospital, Ajman, UAE DOI Creative Commons

Aisha Nur,

Ahmed Osman,

Kumar Kandakurti

и другие.

International Journal of Biomedicine, Год журнала: 2023, Номер 13(4)

Опубликована: Дек. 5, 2023

Background: This study aimed to estimate the levels of C-reactive protein (CRP) and prolactin (PRL) in SARS-CoV2 infection their association with severity COVID-19 among patients Ajman, UAE.Methods Results: cross-sectional was conducted Thumbay Hospital from 2020 2021.The included 71 (55 males 16 females) positive SARS-CoV-2 test results.Nasal swab specimens were collected for on day admission or after one admission.COVID-19 diagnoses determined according New Coronavirus Pneumonia Prevention Control Program (7th edition) published by National Health Commission China (2020).Serum samples upon admission.The PRL level using immune chemiluminescent method DXI 800 Beckman Coulter analyzer.The CRP immunoturbidimetric DXC 700 AU chemistry analyzer.Among patients, great majority men 55(77.5%),38(53.5%)being Indian nationality.In this study, most participants (50.7%) had no history chronic illnesses.In terms severity, 24(33.8%) mild cases, 27(38.0%)had moderate 20(28.2%)had severe cases.Twenty (28.2%) transferred ICU, 19(26.8%)were intubated.The patients' average age 47.58±13.63,CRP -74.30±71.46mg/L, -205.1946±168.52ng/mL.The mean highest compared a statistically significant difference between groups (P=0.000) (P=0.004).The cases cases; however, differences not significant.CRP greater ICU than non-ICU only CRP.We found correlation (r=0.458,P=0.000); weak (r=0.201,P=0.093).A (r=0.461,P=0.03) significant. Conclusion:The current implies that serum might be an important indication development severity.A more extensive larger sample size is needed validate significance disease severity.

Язык: Английский

Impact of COVID-19 on testicular function: a systematic review and meta-analysis DOI Creative Commons
Rossella Cannarella,

Marta Marino,

Andrea Crafa

и другие.

Endocrine, Год журнала: 2024, Номер 85(1), С. 44 - 66

Опубликована: Фев. 12, 2024

Studies investigating the effects of SARS-CoV-2 on male reproductive function are few and heterogeneous, results often conflicting. This systematic review meta-analysis was carried out studies conducted in men with active or anamnestic infection to evaluate its consequences sex hormone profile semen parameters.

Язык: Английский

Процитировано

7

Does COVID-19 affect sperm quality in males? the answer may be yes, but only temporarily DOI Creative Commons
Qi-Feng Zhang, Yuji Zhang, Sheng Wang

и другие.

Virology Journal, Год журнала: 2024, Номер 21(1)

Опубликована: Янв. 23, 2024

Abstract Background The Corona Virus Disease 2019 (COVID-19) pandemic has raised concerns regarding its potential impact on male reproductive health. However, the of COVID-19 sperm quality remains uncertain. This retrospective study aimed to investigate short-term and relatively long-term effects infection quality. Methods A total 85 males with fertility requirements, who underwent semen evaluation at Guilin People’s Hospital between June 2022 July 2023, were included in study. Changes parameters analyzed across three specific timeframes: within 6 months before infection, 3 after 3–6 recovery. Results results revealed that concentration number significantly lower compared before, while recovery period, concentration, count, progressive motility, normal morphology increased. Comparing periods, most significant difference was observed which exhibited a decrease but returned levels from COVID-19. Conclusions These findings suggest may exert some quality, particularly evidenced by decreased post-infection. Fortunately, these appear be temporary, gradual restoration further research is needed explore underlying mechanisms implications changes parameters.

Язык: Английский

Процитировано

5

Possible mechanisms of spermatogenic dysfunction induced by viral infections: Insights from COVID‐19 DOI Creative Commons
Keisuke Okada,

Chanhyon Kin,

Yosuke Yamashita

и другие.

Reproductive Medicine and Biology, Год журнала: 2025, Номер 24(1)

Опубликована: Янв. 1, 2025

Abstract Background As the COVID‐19 pandemic nears resolution in 2024, mechanisms by which SARS‐CoV‐2 and other viral infections induce spermatogenic dysfunction remain poorly understood. This review examines infections, particularly COVID‐19, disrupt spermatogenesis highlights implications for male reproductive health. While reports suggest that caused is mild transient, these findings may have broader applications understanding treating future infections. Methods The PubMed database was searched to identify original articles investigating SARS‐CoV‐2, contribute dysfunction. Main Findings affects testis through multiple mechanisms, including ACE2 receptor‐mediated entry, direct damage, inflammatory response, blood–testis barrier disruption, hormonal imbalance, oxidative stress, impaired spermatogenesis. combination of factors can testicular function complexity effects on Conclusion infection, systemic inflammation, stress. Ongoing research, vaccination efforts, clinical vigilance are essential address challenges develop effective treatment prevention strategies.

Язык: Английский

Процитировано

0

Effect of SARS-CoV-2 infection on sperm telomere length DOI
Murilo Racy Soares,

Rita Carvalho,

Heithor S. Cirino

и другие.

Journal of Assisted Reproduction and Genetics, Год журнала: 2025, Номер unknown

Опубликована: Фев. 11, 2025

Язык: Английский

Процитировано

0

COVID-19 infection was associated with poor sperm quality: a cross-sectional and longitudinal clinical observation study DOI Creative Commons
Lulu Yuan, Wei Sun, Zihan Dong

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Апрель 3, 2025

To ascertain whether COVID-19 infection affects sperm quality and measure the scale of effects. A cross sectional study a longitudinal were conducted during SARS-CoV-2 pandemic (from September 7th 2022 to late January 2023) in China. 604 patients participated study; 140 with 149 unaffected natural controls. The included participants who produce semen sample after COVID-19. positive could provide samples before infection. In addition, by two consecutive over same period as controls for study. Conventional parameters including count, motility, morphology more recent such DNA fragmentation index (DFI) chromatin immaturity observed. study, exposure group demonstrated significantly lower total count (159.58 × 106 vs. 185.42 106, P = 0.042), percentage grade sperms (5.37% 8.45%, 0.009), progressive motility (24.74 ± 14.96% 28.73 16.65%, 0.023), (32.04 18.03% 36.91 20.86%, 0.022), higher DFI (17.50% 11.75%, 0.030) than infection, showed (131.80 173.63 Δd -20.49 0.018 ), ( 2.61% 8.50%, -3.18%, < 0.001), (19.82 13.68% 24.88 14.97%, -5.07 11.94%, 0.001) (26.64 17.35% 32.25 18.69%, -5.62 14.30%, (32.10 21.30% 26.49 18.54%, 5.61 13.71%, 0.039) while negative opposite changes. Finally, 59.29% deteriorated concentration, 57.86% 71.43% Grade sperm, 65.00% 69.29% 75.00% DFI, changes all less 40% (P 0.002). was associated poor quality. findings would be useful clinicians manage men fertility problems suffered

Язык: Английский

Процитировано

0

Pulsatile Gonadotropin-Releasing Hormone Therapy Is Associated With Better Spermatogenic Outcomes than Gonadotropin Therapy in Patients With Pituitary Stalk Interruption Syndrome DOI
Junyi Zhang, Yiyi Zhu, Rui Zhang

и другие.

Endocrine Practice, Год журнала: 2023, Номер 30(2), С. 146 - 154

Опубликована: Ноя. 28, 2023

Язык: Английский

Процитировано

4

Sperm quality and sexual function after the first COVID-19 infection during the omicron surge: an observational study in southwest China DOI Open Access
Tingting Yang, Bo Liu, Xiaohong Luo

и другие.

Translational Andrology and Urology, Год журнала: 2024, Номер 13(9), С. 1835 - 1846

Опубликована: Сен. 1, 2024

As the Omicron variant became dominant coronavirus disease 2019 (COVID-19) strain and threat to human health decreased, impact of COVID-19 on male reproductive semen quality may have changed. In this prospective observational study, we aimed investigate changes in sexual function before after infection by self-controlled study explore influence health.

Язык: Английский

Процитировано

1

Update on andrological effects of SARS‐CoV‐2 infection and COVID‐19: An overview review DOI Creative Commons
Giuseppe Lisco, Anna De Tullio, Maima Matin

и другие.

Andrology, Год журнала: 2024, Номер unknown

Опубликована: Дек. 31, 2024

Evidence indicates a wide range of andrological alterations in patients with the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) infection and Coronavirus Disease 2019 (COVID-19).

Язык: Английский

Процитировано

1

Study of SARS-CoV-2 in semen from asymptomatic donors with the presence of virus in nasopharyngeal swabs DOI

Gemma Alvarez,

M Molina, José Antonio Castilla

и другие.

Reproductive BioMedicine Online, Год журнала: 2023, Номер 47(6), С. 103321 - 103321

Опубликована: Июль 30, 2023

Язык: Английский

Процитировано

3

Impact of COVID‐19 on sperm quality and the prostaglandin and polyamine systems in the seminal fluid DOI
María Eugenia Matzkin,

Celina Beguerie,

Ignacio de Zúñiga

и другие.

Andrology, Год журнала: 2023, Номер 12(5), С. 1078 - 1095

Опубликована: Окт. 24, 2023

Abstract Background The implications of SARS‐CoV‐2 infection on male fertility remain largely unknown. Besides their well‐known pro‐ and anti‐inflammatory actions, prostaglandins polyamines are present in semen, where they play key roles sperm quality. Objectives To analyze semen parameters, oxidative profile the seminal fluid prostaglandin polyamine systems samples collected from individuals without coronavirus disease 2019 diagnosis men who recovered 2019. Materials methods This study compared positive with obtained 1–6 months 7–30 post infection. Semen thiobarbituric acid reactive substances, cyclooxygenase 2 expression by fluorescence immunocytochemistry immunoblotting, levels enzyme immunoassay, ornithine decarboxylase activity a radioactive assay, acetylated thin‐layer chromatography were assessed. Results In both groups men, vitality, total progressive motility, putrescine significantly decreased when uninfected group. contrast, lipid peroxidation, leukocyte‐associated expression, D2 higher than individuals. While concentration morphology, activity, N‐acetylputrescine statistically diminished up to 6 after recovery, these parameters remained unchanged recovery. Coronavirus vaccination did not show negative effects any evaluated. Discussion conclusion Our work provides insights into detrimental impact several some cases, even more year infection, which would be accompanied alterations profiles. Therefore, future treatments targeting pathways could lead successful reinstatement parameters.

Язык: Английский

Процитировано

3