Alcohol Clinical and Experimental Research,
Год журнала:
2024,
Номер
48(4), С. 680 - 691
Опубликована: Март 28, 2024
Abstract
Background
While
sleep
and
circadian
rhythms
are
recognized
contributors
to
the
risk
for
alcohol
use
related
problems,
few
studies
have
examined
whether
objective
measures
can
predict
future
in
humans,
no
such
been
conducted
adults.
This
study
any
baseline
and/or
characteristics
of
otherwise
healthy
adults
predicted
their
over
subsequent
12
months.
Methods
Participants
(21–42
years)
included
28
light
50
heavy
drinkers.
At
baseline,
a
comprehensive
range
self‐reported
sleep/circadian
was
assessed
via
questionnaires,
wrist
actigraphy,
measurement
dim
melatonin
onset
photoreceptor
responsivity.
Following
this,
number
alcoholic
drinks
per
week
binge
drinking
episodes
month
were
quarterly
Anticipated
effects
(stimulation,
sedation,
rewarding
aspects)
also
Analyses
generalized
linear
mixed‐effects
models
causal
mediation
analysis.
Results
Across
measures,
only
insomnia
symptoms
longer
total
time
at
more
binges
(
p
s
<0.02).
There
trend
anticipated
effect
wanting
6‐month
timepoint
mediate
relationship
between
months
=
0.069).
Conclusions
These
results
suggest
that
adults,
symptoms,
even
if
subclinical,
significant
predictor
drinking,
appear
outweigh
influence
factors
on
least
Insomnia
may
be
modifiable
target
reducing
misuse.
Journal of Sleep Research,
Год журнала:
2017,
Номер
26(6), С. 739 - 746
Опубликована: Март 28, 2017
Summary
Using
a
cross‐sectional
probability
sample
with
actigraphy
data
and
two
24‐h
dietary
recalls,
we
quantified
the
association
between
sleep
duration,
continuity,
variability
timing
Alternative
Healthy
Eating
Index‐2010
diet
quality
score
its
components
in
2140
Hispanic
Community
Health
Study/Study
of
Latinos
participants.
The
Index
quality‐2010
ranges
from
0
to
110,
higher
scores
indicating
greater
adherence
guidelines
lower
risk
major
chronic
disease.
None
measures
was
associated
total
caloric
intake
as
assessed
using
recalls.
However,
both
an
increase
duration
efficiency
were
healthier
quality.
Each
standard
deviation
(1.05
h)
(4.99%)
0.30
point
0.28
increase,
respectively,
score.
component
most
strongly
longer
increased
nuts
legumes
intake.
whole
fruit
decreased
sodium
Both
significantly
better
among
US
Hispanic/Latino
adults.
differed,
suggesting
potentially
independent
mechanisms
by
which
each
aspect
impacts
choices.
Longitudinal
research
is
needed
understand
directionality
these
identified
relationships
generalizability
across
other
ethnic
groups.
To
examine
the
effects
of
moderate
sleep
restriction
(SR)
on
body
weight,
composition,
and
metabolic
variables
in
individuals
undergoing
caloric
(CR).
Overweight
or
obese
adults
were
randomized
to
an
8
week
(CR)
regimen
alone
(n
=
15)
combined
with
(CR
+
SR)
21).
All
participants
instructed
restrict
daily
calorie
intake
95
per
cent
their
measured
resting
rate.
Participants
CR
SR
group
also
reduce
time
bed
five
nights
ad
libitum
other
two
each
week.
The
reduced
by
57
±
36
min
day
during
days
increased
59
38
days,
resulting
a
reduction
169
75
groups
lost
similar
amounts
lean
mass,
fat
mass.
However,
proportion
total
mass
as
was
significantly
greater
(p
0.016)
group.
This
than
percentage
at
baseline
for
0.0035),
but
not
Resting
respiratory
quotient
0.033)
only
CR,
fasting
leptin
concentration
0.029).
Approximately
1
hr
led
less
loss
hypocaloric
weight
loss,
despite
loss.
may
adversely
affect
changes
composition
"catch-up"
completely
reverse
it.
ClinicalTrials.gov
(NCT02413866)
To
test
the
hypotheses
that
insufficient
duration,
high
fragmentation,
and
poor
sleep
quality
are
temporally
associated
with
migraine
onset
on
day
immediately
following
period
(day
0)
1).
Abstract
Study
Objectives
Sleep
is
an
emergent,
multi-dimensional
risk
factor
for
diabetes.
duration,
timing,
quality,
and
insomnia
have
been
associated
with
diabetes
glycemic
biomarkers,
but
the
role
of
sleep
regularity
in
development
metabolic
disorders
less
clear.
Methods
We
analyzed
data
from
2107
adults,
aged
19–64
years,
Sueño
ancillary
study
Hispanic
Community
Health
Study/Study
Latinos,
followed
over
a
mean
5.7
years.
Multivariable-adjusted
complex
survey
regression
methods
were
used
to
model
cross-sectional
prospective
associations
between
index
(SRI)
quartiles
(Q1-least
regular,
Q4-most
regular)
(either
laboratory-confirmed
or
self-reported
antidiabetic
medication
use),
baseline
levels
insulin
resistance
(HOMA-IR),
beta-cell
function
(HOMA-β),
hemoglobin
A1c
(HbA1c),
their
changes
time.
Results
Cross-sectionally,
lower
SRI
was
higher
odds
(odds
ratio
[OR]Q1
vs.
Q4
=
1.64,
95%
CI:
0.98–2.74,
ORQ2
1.12,
0.70–1.81,
ORQ3
1.00,
0.62–1.62,
ptrend
0.023).
The
effect
more
pronounced
older
(aged
≥
45
years)
adults
(ORQ1
1.88,
1.14–3.12,
pinteraction
0.060)
compared
younger
ones.
No
statistically
significant
found
incidence,
as
well
HOMA-IR,
HOMA-β,
HbA1c
values,
time
among
not
taking
medication.
Conclusions
Our
results
suggest
that
represents
another
dimension
relevant
risk.
Further
research
needed
elucidate
relative
contribution
dysregulation
pathophysiology.
Alcohol Clinical and Experimental Research,
Год журнала:
2024,
Номер
48(4), С. 680 - 691
Опубликована: Март 28, 2024
Abstract
Background
While
sleep
and
circadian
rhythms
are
recognized
contributors
to
the
risk
for
alcohol
use
related
problems,
few
studies
have
examined
whether
objective
measures
can
predict
future
in
humans,
no
such
been
conducted
adults.
This
study
any
baseline
and/or
characteristics
of
otherwise
healthy
adults
predicted
their
over
subsequent
12
months.
Methods
Participants
(21–42
years)
included
28
light
50
heavy
drinkers.
At
baseline,
a
comprehensive
range
self‐reported
sleep/circadian
was
assessed
via
questionnaires,
wrist
actigraphy,
measurement
dim
melatonin
onset
photoreceptor
responsivity.
Following
this,
number
alcoholic
drinks
per
week
binge
drinking
episodes
month
were
quarterly
Anticipated
effects
(stimulation,
sedation,
rewarding
aspects)
also
Analyses
generalized
linear
mixed‐effects
models
causal
mediation
analysis.
Results
Across
measures,
only
insomnia
symptoms
longer
total
time
at
more
binges
(
p
s
<0.02).
There
trend
anticipated
effect
wanting
6‐month
timepoint
mediate
relationship
between
months
=
0.069).
Conclusions
These
results
suggest
that
adults,
symptoms,
even
if
subclinical,
significant
predictor
drinking,
appear
outweigh
influence
factors
on
least
Insomnia
may
be
modifiable
target
reducing
misuse.