International Journal of Dentistry and Oral Science,
Год журнала:
2021,
Номер
unknown, С. 4388 - 4392
Опубликована: Сен. 21, 2021
Vitamin
K1
(phylloquinone),
K2
(menaquinone),
and
K3
(phylloquinone)
are
the
three
types
of
vitamin
K.
(menadione).Vitamin
is
found
in
both
tissue
bacterial
products
(animal
or
fermented
foods).Vitamin
k2
has
nine
chemical
variations,
with
number
isoprenyl
units
their
side
chains
determining
majority
them.The
most
frequent
form
human
diet
short
chain,
water
soluble
menatetrenone,
which
generated
by
conversion
k1,
as
well
a
derivative
(MK-4).MK-7,
MK-8,
MK-9
long-chain
menaquinones
(longer
than
MK-4)
that
more
prevalent
foods
like
natto,
traditional
Japanese
meal
prepared
from
soya
beans
bacillus
subtilis
var.Anaerobic
bacteria
colon
create
longer-chain
(MK-10
to
MK-13),
but
they
poorly
absorbed
have
minimal
physiological
impact
at
this
level.The
effects
on
overall
dentistry
topic
review.
Foods,
Год журнала:
2022,
Номер
11(19), С. 3094 - 3094
Опубликована: Окт. 5, 2022
Postbiotics
are
non-viable
bacterial
products
or
metabolic
byproducts
produced
by
probiotic
microorganisms
that
have
biologic
activity
in
the
host.
functional
bioactive
compounds,
generated
a
matrix
during
anaerobic
fermentation
of
organic
nutrients
like
prebiotics,
for
generation
energy
form
adenosine
triphosphate.
The
this
sequence
called
postbiotics,
these
low
molecular
weight
soluble
compounds
either
secreted
live
microflora
released
after
microbial
cell
lysis.
A
few
examples
widely
studied
postbiotics
short-chain
fatty
acids,
fragments,
extracellular
polysaccharides,
lysates,
teichoic
acid,
vitamins,
etc.
Presently,
prebiotics
and
probiotics
on
market;
however,
also
gaining
great
deal
attention.
numerous
health
advantages
postbiotic
components
may
soon
lead
to
an
increase
consumer
demand
supplements.
most
recent
research
aspects
food
pharmaceutical
industries
included
review.
review
encompasses
brief
introduction,
classification,
production
technologies,
characterization,
biological
activities,
potential
applications
postbiotics.
Nutrition Reviews,
Год журнала:
2021,
Номер
80(4), С. 677 - 698
Опубликована: Июль 9, 2021
Abstract
Vitamin
K
is
traditionally
connected
with
blood
coagulation,
since
it
needed
for
the
posttranslational
modification
of
7
proteins
involved
in
this
cascade.
However,
also
maturation
another
11
or
12
that
play
different
roles,
encompassing
particular
modulation
calcification
connective
tissues.
Since
process
physiologically
bones,
but
pathological
arteries,
a
great
deal
research
has
been
devoted
to
finding
possible
link
between
vitamin
and
prevention
osteoporosis
cardiovascular
diseases.
Unfortunately,
current
knowledge
does
not
allow
us
make
decisive
conclusion
about
such
link.
One
explanation
diversity
biological
activity
K,
which
single
compound
general
term
covering
natural
plant
animal
forms
(K1
K2)
as
well
their
synthetic
congeners
(K3
K4).
K1
(phylloquinone)
found
several
vegetables.
Menaquinones
(MK4–MK13,
series
compounds
known
are
mostly
bacterial
origin
introduced
into
human
diet
mainly
through
fermented
cheeses.
Current
kinetics
detection,
toxicity
discussed
review.
Antioxidants,
Год журнала:
2018,
Номер
7(1), С. 10 - 10
Опубликована: Янв. 12, 2018
Vitamins
E,
A,
D
and
K
comprise
the
class
of
lipid-soluble
vitamins.
For
vitamins
A
D,
a
metabolic
conversion
precursors
to
active
metabolites
has
already
been
described.
During
metabolism
vitamin
long-chain
(LCMs)
13′-hydroxychromanol
(13′-OH)
13′-carboxychromanol
(13′-COOH)
are
formed
by
oxidative
modification
side-chain.
The
occurrence
these
in
human
serum
indicates
physiological
relevance.
Indeed,
effects
LCMs
on
lipid
metabolism,
apoptosis,
proliferation
inflammatory
actions
as
well
tocopherol
xenobiotic
have
shown.
Interestingly,
there
several
parallels
between
E
D.
recent
findings
that
exert
different
from
their
support
putative
role
regulatory
metabolites.
Hence,
it
could
be
proposed
mode
action
might
mediated
mechanism
similar
If
relevance
this
concept
can
confirmed,
general
activation
via
deduced.
PLoS ONE,
Год журнала:
2020,
Номер
15(3), С. e0229769 - e0229769
Опубликована: Март 9, 2020
Cerebral
ischemia/reperfusion
(I/R)
injury
causes
cognitive
deficits,
excitotoxicity,
neuroinflammation,
oxidative
stress
and
brain
edema.
Vitamin
K2
(Menaquinone
4,
MK-4)
as
a
potent
antioxidant
can
be
good
candidate
to
ameliorate
I/R
consequences.
This
study
focused
on
the
neuroprotective
effects
of
MK-4
for
cerebral
insult
in
rat's
hippocampus.
The
rat
model
was
generated
by
transient
bilateral
common
carotid
artery
occlusion
20
min.
Rats
were
divided
into
control,
I/R,
I/R+DMSO
(solvent
(1%
v/v))
I/R+MK-4
treated
(400
mg/kg,
i.p.)
groups.
Twenty-four
hours
after
induction,
total
water
content,
superoxide
dismutase
(SOD)
activity,
nitrate/nitrite
concentration
neuronal
density
evaluated.
In
addition
quantify
apoptosis
processes,
TUNEL
staining,
well
expression
level
Bax
Bcl2,
assessed.
To
evaluate
astrogliosis
induced
neurotoxicity
GFAP
GLT-1
mRNA
quantified.
Furthermore,
pro-inflammatory
cytokines
including
IL-1β,
IL-6
TNF-α
measured.
Seven
days
post
behavioral
analysis
function,
Nissl
staining
surviving
evaluation,
conducted.
findings
indicated
that
administration
following
improved
anxiety-like
behavior,
short
term
spatial
learning
memory
impairment
I/R.
Also,
able
diminish
increased
apoptotic
cell
density,
Bax/
Bcl2
ratio
addition,
high
nitrate/nitrite,
IL-6,
IL-1β
reduced
administration.
However,
promotes
SOD
activity
model.
demonstrated
rescue
global
consequences
via
its
anti-inflammatory
anti-oxidative
features.
ameliorates
death
processes
leads
neuroprotection.
Journal of Functional Foods,
Год журнала:
2023,
Номер
102, С. 105467 - 105467
Опубликована: Фев. 22, 2023
Pickled
cabbages
(brine-pickling)
and
sauerkraut
(dry-salting)
were
produced
by
adding
the
probiotic
mix
culture
Lb
plantarum
culture,
as
well
spontaneous
fermentation.
During
fermentation,
Lactobacillus
spp,
yeast-mold
count,
total
coliform
bacteria
pH
acidity
followed.
Total
phenolic
content,
ORAC
TEAC
values,
ascorbic
acid
Menaquinone
(MK-4
MK-7)
contents
analyzed
in
fermented
samples.
spp
was
7.82–9.70
cfu/g.
count
higher
culture-added
samples
Sauerkraut
had
values
than
pickled
cabbage
It
found
that
fermentation
contained
amounts
of
MK-4
MK-7.
Color,
odor,
texture,
sourness
overall
evaluation
scores
sensory
evaluation.
Nutrients,
Год журнала:
2023,
Номер
15(2), С. 273 - 273
Опубликована: Янв. 5, 2023
With
over
6
million
coronavirus
pandemic
deaths,
the
African
continent
reported
lowest
death
rate
despite
having
a
high
disease
burden.
The
community’s
resilience
to
has
been
attributed
climate
and
weather
conditions,
herd
immunity,
repeated
exposure
infectious
organisms
that
help
stimulate
immune
system,
disproportionately
large
youth
population.
In
addition,
functional
foods,
herbal
remedies,
dietary
supplements
contain
micronutrients
bioactive
compounds
can
boost
system.
This
review
identified
significant
traditional
fermented
foods
remedies
available
within
with
potential
system
in
epidemics
pandemics.
Methodology:
Databases,
such
as
PubMed,
Web
of
Science,
Scopus,
were
searched
using
relevant
search
terms
identify
medicinal
plants
immune-boosting
or
antiviral
capabilities.
Cereal-based
meat-,
fish-based
dairy-based
containing
antioxidants,
immunomodulatory
effects,
probiotics,
vitamins,
peptides
discussed.
nine
spices
belonging
eight
plant
families
have
antioxidant,
immunomodulatory,
anti-inflammatory,
neuroprotective,
hepatoprotective,
cardioprotective,
properties.
Peptides,
flavonoids,
alkaloids,
sterols,
ascorbic
acid,
minerals,
saponins
are
some
remedies.
Bioactive
food
significantly
support
increase
resistance
against
diseases.
variety
found
on
could
play
an
essential
role
providing
community
diseases
during
should
investigate
nutritional,
herbal,
environmental
factors
healthy
living
longevity.
