G.P.5 Over expression of the LARGE transgene exacerbates muscle pathology in the mdx mouse DOI

Kim E. Wells,

S. Muses,

A. Ruberg

и другие.

Neuromuscular Disorders, Год журнала: 2012, Номер 22(9-10), С. 813 - 813

Опубликована: Авг. 30, 2012

Язык: Английский

Vitamin K2 - Vital for Health and Wellbeing DOI
Adriana V. Díaz, Martin Walker, Joanne P. Webster

и другие.

InTech eBooks, Год журнала: 2017, Номер unknown

Опубликована: Март 22, 2017

This book serves as a comprehensive survey of the impact vitamin K2 on cellular functions and organ systems, indicating that plays an important role in differentiation/preservation various cell phenotypes stimulator and/or mediator interorgan cross talk. Vitamin binds to transcription factor SXR/PXR, thus acting like hormone (very much same manner A D). Therefore, affects multitude it is reckoned be one positive bringing about "longevity" human body, e.g., supporting functions/health different well correcting functioning or even "curing" ailments striking several organs our body.
Kappa - Vital for Health Wellbeing has been produced distributed through support from Kappa Bioscience, Norway.

Язык: Английский

Процитировано

32

Effectiveness of a timed praziquantel treatment of school children in relation to seasonal transmission of urogenital schistosomiasis in Northwestern Tanzania. DOI
Nyanda C. Justine, Humphrey D. Mazigo, Antje Fuß

и другие.

Acta Tropica, Год журнала: 2025, Номер unknown, С. 107530 - 107530

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Vertebral Plasma Cell Tumors in 8 Dogs DOI
Clare Rusbridge, Simon J. Wheeler, Christopher R. Lamb

и другие.

Journal of Veterinary Internal Medicine, Год журнала: 1999, Номер 13(2), С. 126 - 126

Опубликована: Янв. 1, 1999

The case histories of 8 dogs with spinal pain and neurologic deficits associated vertebral plasma cell tumor are reviewed. Four had solitary plasmacytoma, 3 multiple myeloma, 1 dog 2 lesions no evidence disseminated disease. were treated: myeloma received chemotherapy only survived 17 26 months, respectively. Two plasmacytomas the spine radiotherapy: 1st 4 months was euthanized after developing radiation myelopathy; 2nd 65 before myeloma. diagnosis plasmacytoma versus is discussed.

Язык: Английский

Процитировано

46

Chylomicron remnants and oxidised low density lipoprotein have differential effects on the expression of mRNA for genes involved in human macrophage foam cell formation DOI

KellyV. Batt,

Lisa Patel,

Kathleen M. Botham

и другие.

Journal of Molecular Medicine, Год журнала: 2004, Номер 82(7)

Опубликована: Май 19, 2004

Язык: Английский

Процитировано

36

Necrotising fasciitis with sub-periosteal Streptococcus canis infection in two puppies DOI
Sandra Corr, Elvin Kulendra

Veterinary and Comparative Orthopaedics and Traumatology, Год журнала: 2008, Номер 21(05), С. 474 - 477

Опубликована: Янв. 1, 2008

Summary Necrotising fasciitis is an uncommon and potentially devastating disease which has been infrequently reported in animals. This brief communication describes unusual presentation of necrotising two immature Bull Terriers. Both animals were admitted with a history minimal trauma yet rapidly progressive, localising, disproportionate pain. Streptococcus canis was cultured from sub-periosteal fluid-filled pockets surrounding the femur both cases.

Язык: Английский

Процитировано

21

Requirement for ERK1/2 Activation in the Regulation of Progesterone Production in Human Granulosa-Lutein Cells Is Stimulus Specific DOI

Dewa Ayu Made Novia Dewi

Endocrinology, Год журнала: 2002, Номер 143(3), С. 877 - 888

Опубликована: Март 1, 2002

The past three years has seen the launch of a new World Health Organization (WHO) neglected tropical diseases (NTDs) roadmap, together with revised control and elimination guidelines.Across all, there is now clear emphasis on need to incorporate One approach, recognizing critical links between human animal health environment.Schistosomiasis, caused by Schistosoma spp.trematodes, NTD global medical veterinary importance, over 220 million people untold millions livestock currently infected.Its burden remains extremely high in certain regions, particularly within sub-Saharan Africa, despite two decades mass preventive chemotherapy (mass drug administration), predominantly school-aged children.In contrast Asia, any zoonotic component schistosomiasis transmission its implications for disease has, until recently, been largely ignored.Here, we review recent epidemiological, clinical, molecular, modelling work across both Asia Africa.We outline evolutionary history dynamics species, emphasize emerging risk raised wildlife reservoirs viable hybridization schistosomes.To achieve 2030 WHO roadmap targets, truly multi-disciplinary perspective must be implemented.This article part theme issue 'Challenges opportunities fight against diseases: decade from London Declaration NTDs'.

Язык: Английский

Процитировано

18

Investigating Synthetic Oligonucleotide Targeting of Mir31 in Duchenne Muscular Dystrophy DOI Open Access
John Hildyard, Dominic J. Wells

PLoS Currents, Год журнала: 2016, Номер unknown

Опубликована: Янв. 1, 2016

The past three years has seen the launch of a new World Health Organization (WHO) neglected tropical diseases (NTDs) roadmap, together with revised control and elimination guidelines.Across all, there is now clear emphasis on need to incorporate One approach, recognizing critical links between human animal health environment.Schistosomiasis, caused by Schistosoma spp.trematodes, NTD global medical veterinary importance, over 220 million people untold millions livestock currently infected.Its burden remains extremely high in certain regions, particularly within sub-Saharan Africa, despite two decades mass preventive chemotherapy (mass drug administration), predominantly school-aged children.In contrast Asia, any zoonotic component schistosomiasis transmission its implications for disease has, until recently, been largely ignored.Here, we review recent epidemiological, clinical, molecular, modelling work across both Asia Africa.We outline evolutionary history dynamics species, emphasize emerging risk raised wildlife reservoirs viable hybridization schistosomes.To achieve 2030 WHO roadmap targets, truly multi-disciplinary perspective must be implemented.This article part theme issue 'Challenges opportunities fight against diseases: decade from London Declaration NTDs'.

Язык: Английский

Процитировано

7

Chylomicron-remnant-like particles inhibit the basal nitric oxide pathway in porcine coronary artery and aortic endothelial cells DOI

Andrew B. Goulter,

Michael Avella,

Kathleen M. Botham

и другие.

Clinical Science, Год журнала: 2003, Номер 105(3), С. 363 - 371

Опубликована: Сен. 1, 2003

The effects of chylomicron remnants on the activity basally produced nitric oxide (NO) from porcine coronary artery rings and aortic endothelial cells were studied by investigating chylomicron-remnant-like particles (CMR-LPs) containing apolipoprotein E vessel tone arteries cGMP release cells. CMR-LPs oxidized incubation with CuSO4 (10 μM) for 18 h at 37 °C. Nω-nitro-L-arginine (L-NOARG) (oxCMR-LPs), but not native CMR-LPs, increased static (increase in as a percentage induced depolarizing Krebs–;Henseleit solution: L-NOARG, 14.24±2.09; oxCMR-LPs, 4.98±0.88; 0.47±0.21). endothelium removal oxCMR-LPs also all significantly maximum relaxation vessels to S-nitroso-N-acetyl-DL-penicillamine. In addition, reduced amounts released into culture medium 116±12.0 84.2±11.6 fmol/μg cellular protein, mimicking L-NOARG. These results indicate that inhibit activity, production or NO unstimulated mimicked addition L-NOARG these experimental systems, suggesting lipoproteins interfering L-arginine/NO pathway. This study provides further evidence support role development atherosclerosis.

Язык: Английский

Процитировано

14

The role of protein kinase C in regulating equine eosinophil adherence and superoxide production DOI

M. F. Sepulveda,

E.C. Greenaway,

M. Avella

и другие.

Inflammation Research, Год журнала: 2005, Номер 54(3), С. 97 - 105

Опубликована: Март 1, 2005

Язык: Английский

Процитировано

10

A scientifically based profession? DOI Open Access

Lance E. Lanyon

Veterinary Record, Год журнала: 2012, Номер 171(5), С. 128 - 129

Опубликована: Авг. 1, 2012

For the veterinary profession to be truly science based all of its members need engaged, says Lance Lanyon

Язык: Английский

Процитировано

4