anti-Selective Carboacylation of Alkynes via Photoredox/Nickel Dual Catalysis DOI

Xianhua Pan,

Chang-Xin Shi,

Ya-Ping Hou

и другие.

Organic Letters, Год журнала: 2024, Номер 26(44), С. 9498 - 9502

Опубликована: Окт. 31, 2024

Here, we report an intermolecular carboacylation of terminal alkynes with tertiary and secondary alkyltrifluoroborates as well acyl chlorides via photoredox/nickel dual catalysis, affording a varity stereodefined trisubstituted enones in good to excellent yields E stereoselectivity, through radical relay process. This redox-neutral protocol exhibits functional group tolerance, exclusive regio- broad compatibility various alkyltrifluoroborates.

Язык: Английский

A Metal-Catalyzed Tunable Reaction of Ylides with Hydroxylamine Derivatives DOI
Honglin Song,

N. F. Chen,

Banpeng Cao

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Март 25, 2025

In this work, a tunable reaction of metal acyl nitrene with ylides is reported for the divergent synthesis enamides and α,α-dicarbonyl phosphorus ylides. The featured mild conditions, good efficiency, broad generality. particular, resulting could be structurally elaborated into potential useful scaffolds. Mechanism investigation suggests that formation was ascribed to nucleophilic substitution ferric sulfur It believed represents an initial example preparing from iron-catalyzed transfer.

Язык: Английский

Процитировано

0

Application of Lead-Free Metal Halide Perovskite Heterojunctions for the Carbohalogenation of C–C Multiple Bonds DOI Creative Commons
Camilla Callegari,

Costanza Tedesco,

Alessia Corbo

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Апрель 1, 2025

A graphitic carbon nitride/lead-free double perovskite heterojunction (g-C3N4/Cs2AgBiCl6) has been adopted as a heterogeneous photocatalyst under visible light irradiation. The employed material enabled the atom transfer radical addition-type carbohalogenation of multiple C-C bonds, including (internal) alkenes and alkynes, with alkyl halides. protocol showed remarkable functional group tolerance, compatible late-stage functionalization natural pharmaceutical derivatives, could be easily scaled up, delivering >1 g desired products.

Язык: Английский

Процитировано

0

Photoredox/Iron Dual-Catalysis-Enabled [4 + 2] Cyclization of Acyl Nitrene with Alkynes DOI
Shimin Xie,

Shuwang Tang,

Ming Hou

и другие.

Organic Letters, Год журнала: 2024, Номер unknown

Опубликована: Дек. 13, 2024

In this work, the annulation of acyl nitrene with alkynes is reported under photoredox/iron dual-catalysis for synthesis a series isoquninalin-2-ones. The reaction featured high regioselectivity and good generality. particular, resulting isoquinalin-2-ones could be structurally elaborated into several biologically interesting scaffolds. Mechanism investigation suggests that was ascribed to formal [4 + 2] cyclization. It believed represents an initial example preparing isoquinolin-1-ones from ferric peroxyl-catalyzed insertion.

Язык: Английский

Процитировано

1

anti-Selective Carboacylation of Alkynes via Photoredox/Nickel Dual Catalysis DOI

Xianhua Pan,

Chang-Xin Shi,

Ya-Ping Hou

и другие.

Organic Letters, Год журнала: 2024, Номер 26(44), С. 9498 - 9502

Опубликована: Окт. 31, 2024

Here, we report an intermolecular carboacylation of terminal alkynes with tertiary and secondary alkyltrifluoroborates as well acyl chlorides via photoredox/nickel dual catalysis, affording a varity stereodefined trisubstituted enones in good to excellent yields E stereoselectivity, through radical relay process. This redox-neutral protocol exhibits functional group tolerance, exclusive regio- broad compatibility various alkyltrifluoroborates.

Язык: Английский

Процитировано

0