anti-Selective Carboacylation of Alkynes via Photoredox/Nickel Dual Catalysis DOI

Xianhua Pan,

Chang-Xin Shi,

Ya-Ping Hou

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(44), P. 9498 - 9502

Published: Oct. 31, 2024

Here, we report an intermolecular carboacylation of terminal alkynes with tertiary and secondary alkyltrifluoroborates as well acyl chlorides via photoredox/nickel dual catalysis, affording a varity stereodefined trisubstituted enones in good to excellent yields E stereoselectivity, through radical relay process. This redox-neutral protocol exhibits functional group tolerance, exclusive regio- broad compatibility various alkyltrifluoroborates.

Language: Английский

A Metal-Catalyzed Tunable Reaction of Ylides with Hydroxylamine Derivatives DOI
Honglin Song,

N. F. Chen,

Banpeng Cao

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: March 25, 2025

In this work, a tunable reaction of metal acyl nitrene with ylides is reported for the divergent synthesis enamides and α,α-dicarbonyl phosphorus ylides. The featured mild conditions, good efficiency, broad generality. particular, resulting could be structurally elaborated into potential useful scaffolds. Mechanism investigation suggests that formation was ascribed to nucleophilic substitution ferric sulfur It believed represents an initial example preparing from iron-catalyzed transfer.

Language: Английский

Citations

0
Application of Lead-Free Metal Halide Perovskite Heterojunctions for the Carbohalogenation of C–C Multiple Bonds DOI Creative Commons
Camilla Callegari,

Costanza Tedesco,

Alessia Corbo

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

A graphitic carbon nitride/lead-free double perovskite heterojunction (g-C3N4/Cs2AgBiCl6) has been adopted as a heterogeneous photocatalyst under visible light irradiation. The employed material enabled the atom transfer radical addition-type carbohalogenation of multiple C-C bonds, including (internal) alkenes and alkynes, with alkyl halides. protocol showed remarkable functional group tolerance, compatible late-stage functionalization natural pharmaceutical derivatives, could be easily scaled up, delivering >1 g desired products.

Language: Английский

Citations

0
Photoredox/Iron Dual-Catalysis-Enabled [4 + 2] Cyclization of Acyl Nitrene with Alkynes DOI
Shimin Xie,

Shuwang Tang,

Ming Hou

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 13, 2024

In this work, the annulation of acyl nitrene with alkynes is reported under photoredox/iron dual-catalysis for synthesis a series isoquninalin-2-ones. The reaction featured high regioselectivity and good generality. particular, resulting isoquinalin-2-ones could be structurally elaborated into several biologically interesting scaffolds. Mechanism investigation suggests that was ascribed to formal [4 + 2] cyclization. It believed represents an initial example preparing isoquinolin-1-ones from ferric peroxyl-catalyzed insertion.

Language: Английский

Citations

1
anti-Selective Carboacylation of Alkynes via Photoredox/Nickel Dual Catalysis DOI

Xianhua Pan,

Chang-Xin Shi,

Ya-Ping Hou

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(44), P. 9498 - 9502

Published: Oct. 31, 2024

Here, we report an intermolecular carboacylation of terminal alkynes with tertiary and secondary alkyltrifluoroborates as well acyl chlorides via photoredox/nickel dual catalysis, affording a varity stereodefined trisubstituted enones in good to excellent yields E stereoselectivity, through radical relay process. This redox-neutral protocol exhibits functional group tolerance, exclusive regio- broad compatibility various alkyltrifluoroborates.

Language: Английский

Citations

0