Recent advances in radical-mediated intermolecular (4 + 2) cycloaddition
Organic & Biomolecular Chemistry,
Год журнала:
2023,
Номер
21(30), С. 6068 - 6082
Опубликована: Янв. 1, 2023
On
the
basis
of
types
radicals
that
initiate
different
intermolecular
(4
+
2)
cycloaddition
processes,
we
classify
them
into
five
types,
and
this
review
places
special
emphasis
on
reaction
design
mechanisms.
Язык: Английский
Transition-Metal-Catalyzed Dehydrogenative (3 + 2) Annulation of Aromatic Compounds: Synthesis of Indenes and Indanes via Dual Functionalization of Benzylic and ortho C–H Bonds
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(20), С. 14264 - 14273
Опубликована: Окт. 9, 2023
Intermolecular
(3
+
2)
annulation
emerges
as
a
potent
approach
for
constructing
5-membered
carbocycles
through
the
fusion
of
two
distinct
components.
This
synopsis
encapsulates
recent
strides
in
realm
transition-metal-catalyzed
dehydrogenative
aromatic
hydrocarbons,
achieved
dual
functionalization
benzylic
and
ortho
C–H
bonds.
Encompassing
three
pivotal
strategies,
namely,
(i)
bond
activation,
(ii)
oxidation,
(iii)
π-coordination
this
review
offers
an
overview
field's
developments.
Язык: Английский
Radical Difunctionalization of Unsaturated Hydrocarbons Employing the Same Functional Reagent
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
366(17), С. 3524 - 3541
Опубликована: Июль 3, 2024
Abstract
The
radical
difunctionalization
of
unsaturated
hydrocarbons
serves
as
an
efficient
means
to
rapidly
construct
molecular
skeletons
and
synthesize‐highly
valuable
compounds.
In
this
transformational
process,
diverse
positions
within
are
sequentially
functionalized
by
a
single
precursor
reagent,
thereby
achieving
highly
selective
transformations
that
promote
atom
economy.
Furthermore,
approach
minimizes
the
generation
numerous
byproducts
stemming
from
cross‐coupling
reactions
between
reactants,
owing
reduction
number
participating
components.
Therefore,
review
provides
in‐depth
analysis
utilizing
functional
reagent
in
recent
decades.
discussion
is
based
on
eight
different
classes
(carbon‐,
nitrogen‐,
phosphine‐,
oxygen‐,
sulfur‐,
selenium‐,
tellurium‐,
chlorine‐centered
radicals),
emphasizing
mechanism
specific
difunctionalization.
It
also
analyzes
detail
regulation
key
factors
such
regional
selectivity,
unique
insights
into
reaction
transformations.
Язык: Английский
Vinyl radicals in transition metal-catalyzed organic transformations
Mu-Han Li,
Xiao-Rong Shu,
Yue-Jiao Lu
и другие.
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
11(18), С. 5202 - 5231
Опубликована: Янв. 1, 2024
We
summarize
the
advancements
in
transition
metal-catalyzed
organic
transformations
involving
vinyl
radicals
and
provide
a
categorical
overview
based
on
reaction
types.
Язык: Английский
Copper and Photocatalytic Synergistic Strategies for Radical Cyclization Reactions
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
366(19), С. 4000 - 4016
Опубликована: Июль 30, 2024
Abstract
The
rapid
development
of
photo‐synergistic
transition
metal
catalytic
systems
has
provided
a
green
paradigm
to
complement
thermal
methods.
However,
the
most
commonly
used
iridium
or
ruthenium
complexes
involve
expensive
in
nature,
contrast
abundant
copper
elements
earth's
crust,
which
are
highly
valued
for
their
unique
electronic
structure
and
light‐absorbing
properties.
Recently,
application
photocatalytic
synergistic
strategies
radical
cyclization
reactions
progressed
considerably,
leading
renaissance
synthesis
functional
natural
products,
drugs
analogues,
but
summary
work
addressing
this
aspect
not
been
reported.
In
review,
we
briefly
analyze
effect
ligand
choice
on
some
inorganic
salts
even
light
sources.
We
then
summarize
classify
them
into
three
categories,
C,
N
O
radicals,
according
class
central
atom
each
work,
category
will
be
elaborated
turn
from
coordination
via
Cu
catalysts,
direct
other
mode.
For
individual
more
complex
reactions,
mechanisms
explored
discussed.
Язык: Английский