The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Янв. 9, 2025
This study explores the deoxygenation of pyridine N-oxides and presents a one-step photoredox method for direct synthesis 2-hydroxymethylated pyridines from N-oxides. Mechanism studies elucidate role catalyst provide evidence possible electron transfer process formation key radicals. A range derivatives, particularly 2-hydroxymethyl-substituted pyridines, which may be difficult to obtain, can synthesized in single step.
Язык: Английский