Visible Light-Induced Divergent Deoxygenation/Hydroxymethylation of Pyridine N-Oxides DOI
Changhao Feng, Hao Guo, Aishun Ding

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 9, 2025

This study explores the deoxygenation of pyridine N-oxides and presents a one-step photoredox method for direct synthesis 2-hydroxymethylated pyridines from N-oxides. Mechanism studies elucidate role catalyst provide evidence possible electron transfer process formation key radicals. A range derivatives, particularly 2-hydroxymethyl-substituted pyridines, which may be difficult to obtain, can synthesized in single step.

Language: Английский

Visible Light-Induced Divergent Deoxygenation/Hydroxymethylation of Pyridine N-Oxides DOI
Changhao Feng, Hao Guo, Aishun Ding

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 9, 2025

This study explores the deoxygenation of pyridine N-oxides and presents a one-step photoredox method for direct synthesis 2-hydroxymethylated pyridines from N-oxides. Mechanism studies elucidate role catalyst provide evidence possible electron transfer process formation key radicals. A range derivatives, particularly 2-hydroxymethyl-substituted pyridines, which may be difficult to obtain, can synthesized in single step.

Language: Английский

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