Translational Pediatrics,
Год журнала:
2024,
Номер
13(2), С. 318 - 328
Опубликована: Фев. 1, 2024
In
the
context
of
global
pandemic
coronavirus
disease
2019
(COVID-19),
more
than
700
million
infections
and
millions
deaths
have
occurred
in
countries
around
world.
Currently,
two
main
sequelae
this
are
considered
to
occur
children,
namely,
multi-system
inflammatory
syndrome
children
long
COVID.
Among
these
two,
incidence
COVID
is
higher
its
impact
on
population
extensive,
which
focus
us.
However,
due
lack
relevant
studies
limitations
most
studies,
COVID-19
infection
lag
behind
those
adults,
but
they
begun
attract
attention
some
clinicians
researchers.
We
aim
summarize
current
knowledge
helping
pediatricians
researchers
better
understand
providing
guidance
research
clinical
treatment
it.
Clinical and Experimental Medicine,
Год журнала:
2024,
Номер
24(1)
Опубликована: Янв. 17, 2024
Abstract
Long
Covid-19
syndrome
(LCS)
manifests
with
a
wide
range
of
clinical
symptoms,
yet
the
factors
associated
LCS
remain
poorly
understood.
The
current
study
aimed
to
investigate
relationships
that
demographic
characteristics,
history,
laboratory
indicators,
and
frequency
HLA-I
alleles
have
likelihood
developing
LCS.
We
extracted
characteristics
histories
from
medical
records
88
cases
(LCS
+
group)
96
individuals
without
−
group).
Furthermore,
we
evaluated
serum
levels
interleukin
(IL)-6
tumor
necrosis
factor-α,
parameters,
frequencies
alleles.
Following
this
used
multiple
logistic
regression
association
these
variables
had
Subjects
in
group
were
more
likely
experienced
severe
symptoms
higher
body
mass
index
(BMI),
white
blood
cell,
lymphocyte
counts,
C-reactive
protein
(CRP),
IL-6
than
those
(for
all:
P
<
0.05).
Moreover,
HLA-A*11,
-B*14,
-B*38,
-B*50,
-C*07
After
adjusting
for
most
important
variables,
suffering
was
significantly
BMI,
CRP,
IL-6,
alleles,
as
well
positive
history
Our
showed
during
acute
phase
disease,
elevated
CRP
levels,
all
an
increased
Frontiers in Public Health,
Год журнала:
2024,
Номер
12
Опубликована: Март 21, 2024
Introduction
Long
COVID
patients
experience
a
decrease
in
their
quality
of
life
due
to
the
symptomatology
produced
by
disease.
It
is
also
important
understand
how
long
affects
both
men
and
women.
The
objective
this
study
examine
impact
on
Spanish
adults
from
gender
perspective.
Methods
An
observational
cross-sectional
was
carried
out.
Participants
were
able
complete
an
online
questionnaire
using
platform.
A
sample
206
people
participated
study.
Results
80.6%
women
with
mean
age
46.51
(±8.28)
19.4%
48.03
(±9.50).
medium
score
PAC19-QoL
test
141.47
(±24.96)
segmented
gender,
141.65
(±23.95)
for
140.82
(±28.66)
men.
most
common
symptoms
muscle
joint
pain
(94.6%),
fatigue
(94.0%),
discomfort
(92.2%),
difficulty
concentrating
(91.0%),
memory
loss
(88.6%).
For
included
(97.5%)
occupying
first
position,
(92.0%),
(90.0%),
mood
disturbances
(87.5%).
chi-square
showed
statistical
significance
(
p
<
0.005)
socio-demographic
information,
scores,
intensities.
Conclusion
This
shows
that
there
are
differences
way
experienced.
Nutrients,
Год журнала:
2024,
Номер
16(11), С. 1545 - 1545
Опубликована: Май 21, 2024
Myalgic
encephalomyelitis,
also
known
as
chronic
fatigue
syndrome
(ME/CFS),
and
long
COVID
are
complex,
multisystemic
long-term
disabling
conditions
characterized
by
debilitating
post-exertional
malaise
other
core
symptoms
related
to
immune
dysregulation
resultant
from
post-viral
infection,
including
mitochondrial
dysfunction,
neuroinflammation
gut
dysbiosis.
The
reported
associations
between
altered
microbiota
composition
cardinal
of
ME/CFS
suggest
that
the
use
microbial
preparations,
such
probiotics,
restoring
homeostasis
brain–immune–gut
axis,
may
help
in
management
both
conditions.
Therefore,
this
review
aims
investigate
implications
alerted
microbiome
assess
evidence
supporting
microbial-based
synbiotics,
postbiotics
alone
and/or
combination
with
nutraceuticals
fatigue,
inflammation
neuropsychiatric
gastrointestinal
among
patients
COVID.
Translational Pediatrics,
Год журнала:
2024,
Номер
13(2), С. 318 - 328
Опубликована: Фев. 1, 2024
In
the
context
of
global
pandemic
coronavirus
disease
2019
(COVID-19),
more
than
700
million
infections
and
millions
deaths
have
occurred
in
countries
around
world.
Currently,
two
main
sequelae
this
are
considered
to
occur
children,
namely,
multi-system
inflammatory
syndrome
children
long
COVID.
Among
these
two,
incidence
COVID
is
higher
its
impact
on
population
extensive,
which
focus
us.
However,
due
lack
relevant
studies
limitations
most
studies,
COVID-19
infection
lag
behind
those
adults,
but
they
begun
attract
attention
some
clinicians
researchers.
We
aim
summarize
current
knowledge
helping
pediatricians
researchers
better
understand
providing
guidance
research
clinical
treatment
it.
