A Real-Life Study in Patients Newly Diagnosed with Autoimmune Hashimoto’s Thyroiditis: Analysis of Asthenia as Admission Complaint DOI Creative Commons

Ana Valea,

Mihai Costăchescu,

Mihaela Stanciu

и другие.

Life, Год журнала: 2024, Номер 14(11), С. 1380 - 1380

Опубликована: Окт. 27, 2024

Background: Amid the large panel of autoimmune thyroid diseases, Hashimoto’s thyroiditis (HT) represents a major point across multidisciplinary daily practice. When it comes to clinical picture, particularly in regard asthenia (also described as “fatigue” or “decreased energy”), differential diagnosis is challenging, and meticulous anamnesis should be backed up by focused lab investigations. Our objective was analyze newly diagnosed patients with HT relationship presence an admission complaint. Methods: This retrospective, multi-centric, real-life study conducted secondary endocrine units (university hospitals) from July 2022 2023. The exclusion criteria were COVID-19 infection; active malignancy, etc. Results: cohort (N = 120) included group (AS, 49.2%) non-AS similar age (49.3 ± 14.7 vs. 47.1 14.8 y, p 0.426). Headache more frequent AS (35.6% 18%, 0.03). Thyroid function HT-related antibodies assays between groups show no correlation serum total cholesterol triglycerides, respectively. TSH levels did not vary among sub-groups (p 0.701). One third studied population affected hypothyroidism (TSH > 4.5 μIU/mL), being seen at higher rate (39%) (23%). Total positively correlated patients’ (r 0.180, 0.049) triglycerides 120; r 0.324, < 0.001), found only 0.246, 0.006, respectively, 0.319, 0.001). Conclusions: analysis pinpointed fact that, practice, complaint seems less indicator underlying dysfunction level against without full picture thyrotoxicosis myxoedema.

Язык: Английский

Long COVID science, research and policy DOI Creative Commons
Ziyad Al‐Aly, Hannah Davis, Lisa McCorkell

и другие.

Nature Medicine, Год журнала: 2024, Номер 30(8), С. 2148 - 2164

Опубликована: Авг. 1, 2024

Long COVID represents the constellation of post-acute and long-term health effects caused by SARS-CoV-2 infection; it is a complex, multisystem disorder that can affect nearly every organ system be severely disabling. The cumulative global incidence long around 400 million individuals, which estimated to have an annual economic impact approximately $1 trillion-equivalent about 1% economy. Several mechanistic pathways are implicated in COVID, including viral persistence, immune dysregulation, mitochondrial dysfunction, complement endothelial inflammation microbiome dysbiosis. devastating impacts on individual lives and, due its complexity prevalence, also has major ramifications for systems economies, even threatening progress toward achieving Sustainable Development Goals. Addressing challenge requires ambitious coordinated-but so far absent-global research policy response strategy. In this interdisciplinary review, we provide synthesis state scientific evidence assess human health, systems, economy metrics, forward-looking roadmap.

Язык: Английский

Процитировано

106
Long COVID Research, 2020–2024: A PubMed-Based Bibliometric Analysis DOI Open Access
Cristina Honorato‐Cia, Elena Cacho‐Asenjo, Antonio Martínez-Simón

и другие.

Healthcare, Год журнала: 2025, Номер 13(3), С. 298 - 298

Опубликована: Фев. 1, 2025

Long COVID is a SARS-CoV-2 infection-associated chronic condition with great potential to impact health and socioeconomic outcomes. The research efforts face the challenges related long have resulted in substantial amount of publications, which warrants need for bibliometric profiling. This large-scale PubMed-based analysis more than 390,000 COVID-19 publications. overall aim was update profile publications comparison rest scientific literature through December 2024. estimated proportion relatively low (2.3% all publications), although cumulative frequency (n = 8928) continues pose challenge proper information management. Currently, “treatment” “mechanism” appear be most predominant topics literature. Interestingly, this evaluation revealed distinctive literature, clear preponderance “case report” when compared other also identified ranked prolific journals production COVID-related study may improve visibility contribute management growing knowledge on COVID.

Язык: Английский

Процитировано

1
Printable molecule-selective core–shell nanoparticles for wearable and implantable sensing DOI
Minqiang Wang, Cui Ye, Yiran Yang

и другие.

Nature Materials, Год журнала: 2025, Номер unknown

Опубликована: Фев. 3, 2025

Язык: Английский

Процитировано

1
A framework of research priorities in COVID rehabilitation from the Rehabilitation Science Research Network for COVID: an international consultation involving qualitative and quantitative research DOI Creative Commons
Kelly K. O’Brien, Kiera McDuff, Vijay Kumar Chattu

и другие.

Disability and Rehabilitation, Год журнала: 2024, Номер unknown, С. 1 - 10

Опубликована: Июль 24, 2024

Purpose To identify research priorities related to COVID rehabilitation from the perspectives of persons with lived experiences, clinicians, researchers, community organization and policy representatives.

Язык: Английский

Процитировано

4
Interventions for Long COVID: A Narrative Review DOI
Ilya Ivlev, Jesse Wagner, Taylor Phillips

и другие.

Journal of General Internal Medicine, Год журнала: 2025, Номер unknown

Опубликована: Фев. 21, 2025

Язык: Английский

Процитировано

0
Adult Long Coronavirus Disease 2019 DOI
Ivette F. Emery, Clifford J. Rosen

Infectious Disease Clinics of North America, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Minority health social vulnerability index and long COVID illness among a statewide, population-based study of adults with polymerase chain reaction-confirmed SARS-CoV-2 DOI Creative Commons
Soomin Ryu, Kristi L. Allgood, Yanmei Xie

и другие.

Archives of Public Health, Год журнала: 2025, Номер 83(1)

Опубликована: Март 10, 2025

The COVID-19 pandemic has disproportionately affected socially vulnerable communities. Some individuals experience persistent symptoms and conditions of illness known as long COVID. As little research examined how social vulnerability is related to COVID, we studied this topic using Minority Health Social Vulnerability Index (MHSVI), specifically created for the in U.S. We merged county-level MHSVI data with population-based Michigan adults PCR-confirmed SARS-CoV-2 infection between March 2020 May 2022 based on respondents' county residence. relationship (binary: high ≥ 75th percentile) two COVID measurements, assessed a median 18.8 months after their initial infection: (1) ongoing (yes/no) (2) diagnosis (yes/no). conducted modified Poisson regression models robust standard errors estimate prevalence ratio (PR) associations overall by six themes (socioeconomic status, household composition/disability, minority/language, housing type/transportation, healthcare access, medical vulnerability), adjusting individual-level covariates. Living counties was not associated or diagnosis. However, differed theme MHSVI: respondents highly had 1.32 times higher (95% CI:1.12 − 1.57). There were no statistically significant other adjustment Our findings suggest importance upstream determinants health during public emergencies provide evidence that medically communities need additional resources cope among residents.

Язык: Английский

Процитировано

0
Patient Perspectives on the Care in a Long COVID Outpatient Clinic—A Regional Qualitative Analysis from Germany DOI Open Access

Lea Alexandra Gölz,

Regina Poß-Doering, Uta Merle

и другие.

Healthcare, Год журнала: 2025, Номер 13(7), С. 818 - 818

Опубликована: Апрель 3, 2025

Background/Objectives: Long COVID specialized outpatient clinics (sOCs), which are part of the recommended long care, usually face high demand. Few studies focused on experience care in such facilities Germany. This study investigated how patients a sOC at German university hospital. Methods: Semi-structured interviews were conducted with attending this clinic between October 2022 and January 2023. Data analysis was based thematic analysis. Results: The themes from 14 (F = 11, M 3) could be broadly categorized into statements pathway to sOC, provided sOC. Findings show that patients' expectations appointment shaped by previous experiences mainly perceived as inadequate. Care predominantly competent, empathetic relevant for further coping disease. A deterioration health directly related consultation (classifiable post-exertional malaise) frequently described, need ongoing consultation. Conclusions: Overall, findings point adaptations identifying optimized models tailoring them limited resources. includes measures improve outside

Язык: Английский

Процитировано

0
MyGuide long COVID: An online self-management tool for people with long COVID DOI Creative Commons
Hiten Naik,

Kyla Pongratz,

Michelle Malbeuf

и другие.

Internet Interventions, Год журнала: 2025, Номер unknown, С. 100825 - 100825

Опубликована: Апрель 1, 2025

Long COVID is a relatively new condition for which patients are asked to employ self-management strategies manage their symptoms. However, it can be challenging individuals with long find reliable and actionable resources. The objective of this project was develop an online tool that patient-centered, accessible, customizable meet individual needs. MyGuide (www.longCOVIDguide.ca) developed in British Columbia (BC), Canada, by team included clinicians patient partners. Site visitors answer questions about symptoms, generates curated set resources tailored Since its launch August 2023, Google Analytics has been used monitor website activity. Within the first year, had 52,578 total page views 8570 users. most popular method access computer (56.3 % users), represented city Vancouver, BC (23.5 users). topics were "Post Exertional Malaise" (1339 sessions) "What COVID?" (1257 sessions). An support chronic disease successfully co-developed partners engagement tracked using web analytics.

Язык: Английский

Процитировано

0
Health and social service provider perspectives on challenges, approaches, and recommendations for treating long COVID: a qualitative study of Canadian provider experiences DOI Creative Commons

Anh T. P. Nguyen,

Chantal F. Ski, David R. Thompson

и другие.

BMC Health Services Research, Год журнала: 2025, Номер 25(1)

Опубликована: Апрель 8, 2025

Many people who contract the SAR-CoV-2 virus present with multiple persistent and debilitating physical, cognitive mental health symptoms that endure beyond acute infection period. This new syndrome - generally referred to as long COVID negatively affects patients' emotional wellbeing quality of life, presents a major challenge for treatment providers. Considering lack evidence-based supports, this qualitative descriptive study explores experiences Canadian social service providers working individuals COVID, well their suggestions intervention development. Twenty between ages 29 57 across Canada completed virtual individual interviews discuss care recommendations COVID. Participants were from range sectors, including primary care, rehabilitation, health, community support. Interviews recorded, transcribed, analyzed using codebook thematic analysis. Four themes illustrated providers' (1) selecting personalized treatments based on patient presentation similar conditions amidst uncertainty; services, (2) building an integrated model care; (3) providing holistic support patients families through psychoeducation daily living resources; (4) caring in are adopting approaches address symptom persistence face considerable knowledge gap. A comprehensive, pathway is needed physical psychosocial while increasing provider preparedness treat complex condition.

Язык: Английский

Процитировано

0