A shared neural code for perceiving and remembering social interactions in the human superior temporal sulcus

Neuropsychologia, Год журнала: 2024, Номер 196, С. 108823 - 108823

Опубликована: Фев. 10, 2024

Recognizing and remembering social information is a crucial cognitive skill. Neural patterns in the superior temporal sulcus (STS) support our ability to perceive others' interactions. However, despite prominence of interactions memory, neural basis still unknown. To fill this gap, we investigated brain mechanisms underlying memory during free spoken recall naturalistic movie. By applying machine learning-based fMRI encoding analyses densely labeled movie data found that subset STS activity evoked by viewing predicted responses not only held-out data, but also recall. These results provide first evidence reinstated response specific content its reactivation underlies remember findings further suggest contains representations are perceptually driven, more abstract or conceptual nature.

Язык: Английский

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Memory reactivation and suppression modulate integration of the semantic features of related memories in hippocampus

Cerebral Cortex, Год журнала: 2023, Номер 33(14), С. 9020 - 9037

Опубликована: Июнь 1, 2023

Abstract Encoding an event that overlaps with a previous experience may involve reactivating existing memory and integrating it new information or suppressing the to promote formation of distinct, representation. We used fMRI during overlapping encoding track reactivation suppression individual, related memories. further model semantic knowledge based on Wikipedia quantify both integrated memories containing features events. Representational similarity analysis revealed prior in posterior medial prefrontal cortex (pmPFC) supported integration learning. Moreover, anterior hippocampus (aHPC) formed representations combining found evidence aHPC be modulated trial-by-trial basis by interactions between ventrolateral PFC mPFC, item-specific mPFC inhibiting hippocampal integration. These results suggest PFC-mediated control processes determine availability specific relevant learning, thus impacting

Язык: Английский

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The causal structure and computational value of narratives

Trends in Cognitive Sciences, Год журнала: 2024, Номер 28(8), С. 769 - 781

Опубликована: Май 10, 2024

Язык: Английский

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Causal and Chronological Relationships Predict Memory Organization for Nonlinear Narratives

Journal of Cognitive Neuroscience, Год журнала: 2024, Номер 36(11), С. 2368 - 2385

Опубликована: Янв. 1, 2024

Abstract While recounting an experience, one can employ multiple strategies to transition from part the next. For instance, if event was learned out of linear order, recall events according time they were (temporal), similar (semantic), occurring nearby in (chronological), or produced by current (causal). To disentangle importance these factors, we had participants watch nonlinear narrative, Memento, under different task instructions and presentation orders. each scene film, also separately computed semantic causal networks. We then contrasted evidence for temporal, semantic, chronological, during recall. Critically, there stronger chronological than temporal strategies. Moreover, outperformed even when asked film presented underscoring fundamental nature structure scaffolding understanding organizing Nevertheless, still marginally predicted transitions, suggesting it operates as a weak signal presence more salient forms structure. In addition, network properties memorability, including role incoming causes its outgoing effects. summary, findings highlight accounting complex, networks knowledge building memory.

Язык: Английский

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Fast-timescale hippocampal processes bridge between slowly unfurling neocortical states during memory search

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2025, Номер unknown

Опубликована: Фев. 13, 2025

Prior behavioral work showed that event structure plays a key role in our ability to mentally search through memories of continuous naturalistic experience. We hypothesized that, neurally, this mem- ory process involves division labor between slowly un- furling neocortical states representing knowledge and fast hippocampal-neocortical communication supports retrieval new information at transitions events. To test this, we tracked slow neural state-patterns sample ten patients under- going intracranial electroencephalography as they viewed movie then searched their structured in- terview. As answered questions ("after X, when does Y happen next?"), from movie-viewing were reinstated neocortex; during memory-search, unfurled forward di- rection. Moments state-transition marked by low-frequency power decreases cortex preceded hip- pocampus correlated with reinstatement. Connectivity-analysis revealed information-flow hippocampus underpinning state-transitions. Together, these results support hypothesis hippocampal processes bridge memory search.

Язык: Английский

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Neural codes track prior events in a narrative and predict subsequent memory for details

Communications Psychology, Год журнала: 2025, Номер 3(1)

Опубликована: Фев. 16, 2025

Throughout our lives, we learn schemas that specify what types of events to expect in particular contexts and the temporal order which these usually occur. Here, first goal was investigate how such context-dependent structures are represented brain during processing temporally extended events. To accomplish this, ran a 2-day fMRI study (N = 40) exposed participants many unique animated videos weddings composed sequences rituals; each sequence originated from one two fictional cultures (North South), where rituals were shared across cultures, but transition structure between differed cultures. The results, obtained using representational similarity analysis, revealed is multiple ways parallel, including distinct neural representations for culture, sequences, past current within sequence. Our second test hypothesis schema scaffold memory specific details. In keeping with this hypothesis, found strength representation North/South wedding predicted subsequent episodic details wedding.

Язык: Английский

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A non-Hebbian code for episodic memory

Science Advances, Год журнала: 2025, Номер 11(8)

Опубликована: Фев. 21, 2025

Hebbian plasticity has long dominated neurobiological models of memory formation. Yet, rules operating on one-shot episodic timescales rarely depend both pre- and postsynaptic spiking, challenging theory in this crucial regime. Here, we present an model governed by a simpler rule depending only presynaptic activity. We show that rule, capitalizing high-dimensional neural activity with restricted transitions, naturally stores episodes as paths through complex state spaces like those underlying world model. The resulting traces, which term path vectors, are highly expressive decodable odor-tracking algorithm. vectors robust alternatives to support sequential associative recall, along policy learning, shed light specific hippocampal rules. Thus, non-Hebbian is sufficient for flexible learning well-suited encode policies

Язык: Английский

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First-Person Spoken Narratives Elicit Consistent Event Structures in the Angular Gyrus.

Cortex, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

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On the Application of Developmental Cognitive Neuroscience in Educational Environments

Brain Sciences, Год журнала: 2022, Номер 12(11), С. 1501 - 1501

Опубликована: Ноя. 4, 2022

The paper overviews components of neurologic processing efficiencies to develop innovative methodologies and thinking school-based applications changes in educational leadership based on sound findings the cognitive neurosciences applied schools learners. Systems science can allow us better manage classroom-based learning instruction basis relatively easily evaluated or inefficiencies optimization instead simply examining achievement. “Medicalizing” process with concepts such as “learning disability” employing grading methods pass-fail does little aid understanding processes that learners employ acquire, integrate, remember, apply information learned. endeavors overview provided reference tools be employed a focus nervous system-based strategic approaches classroom learning.

Язык: Английский

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The autobiographical memory system and chronic pain: A neurocognitive framework for the initiation and maintenance of chronic pain

Neuroscience & Biobehavioral Reviews, Год журнала: 2024, Номер 162, С. 105736 - 105736

Опубликована: Май 23, 2024

Chronic pain affects approximately 20% of the world's population, exerting a substantial burden on affected individual, their families, and healthcare systems globally. Deficits in autobiographical memory have been identified among individuals living with chronic pain, even found to pose risk for transition chronicity. Recent neuroimaging studies simultaneously implicated common brain regions central processing maintenance susceptibility pain. The present review proposes novel neurocognitive framework explained by mechanisms underlying system. Here, we 1) summarize current literature 2) discuss role hippocampus cortical including ventromedial prefrontal cortex, anterior temporal lobe, amygdala relation memory, schemas, emotional processing, 3) synthesize these findings that explains relationships implications patients' outcomes, 4) propose translational directions prevention, management, treatment

Язык: Английский

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