Connectome harmonic decomposition tracks the presence of disconnected consciousness during ketamine-induced unresponsiveness
British Journal of Anaesthesia,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 1, 2025
Язык: Английский
Exploring End-of-Life Experiences and Consciousness through the Lens of Psychedelics
ACS Pharmacology & Translational Science,
Год журнала:
2025,
Номер
8(3), С. 907 - 909
Опубликована: Фев. 26, 2025
Exploring
dying
through
the
lens
of
psychedelic
experiences
offers
transformative
perspectives
on
end-of-life
process,
potentially
alleviating
existential
distress
and
enriching
quality
life
for
those
nearing
death.
Their
potential
in
palliative
care,
therapy,
spiritual
exploration
is
increasingly
recognized,
promising
to
revolutionize
understanding
care.
Язык: Английский
Functional ultrasound detects frequency-specific acute and delayed S-ketamine effects in the healthy mouse brain
Frontiers in Neuroscience,
Год журнала:
2023,
Номер
17
Опубликована: Май 17, 2023
S-ketamine
has
received
great
interest
due
to
both
its
antidepressant
effects
and
potential
induce
psychosis
when
administered
subchronically.
However,
no
studies
have
investigated
acute
delayed
using
Язык: Английский
Cortical high-frequency oscillations (≈ 110 Hz) in cats are state-dependent and enhanced by a subanesthetic dose of ketamine
Behavioural Brain Research,
Год журнала:
2024,
Номер
476, С. 115231 - 115231
Опубликована: Авг. 30, 2024
Язык: Английский
Functional Connectivity Biomarkers in Schizophrenia
Advances in neurobiology,
Год журнала:
2024,
Номер
unknown, С. 237 - 283
Опубликована: Янв. 1, 2024
Язык: Английский
Disruption of consciousness depends on insight in OCD and on positive symptoms in schizophrenia
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 3, 2024
Disruption
of
conscious
access
contributes
to
the
advent
psychotic
symptoms
in
schizophrenia
but
could
also
explain
lack
insight
other
psychiatric
disorders.
In
this
study,
we
explored
how
and
related
disruption
consciousness.
We
consciousness
patients
with
schizophrenia,
obsessive-compulsive
disorder
(OCD)
good
vs.
poor
matched
controls.
Participants
underwent
clinical
assessments
performed
a
visual
masking
task
allowing
us
measure
individual
threshold.
used
principal
component
analysis
reduce
symptom
dimensionality
measures
symptomatology.
found
that
dimensions
be
well
summarized
by
restricted
set
components
which
correlated
extent
disruption.
More
specifically,
positive
were
associated
impaired
whereas
level
delineated
two
subtypes
OCD
patients,
those
who
had
impairments
similar
resemble
healthy
Our
study
provides
new
insights
about
disorders,
showing
it
relates
OCD.
OCD,
revealed
distinct
subgroup
sharing
neuropathological
features
schizophrenia.
findings
refine
mapping
between
cognition,
paving
way
for
better
treatment
selection.
Язык: Английский
Cortical High-Frequency Oscillations (≈ 110 Hz) in Cats are State-Dependent and Enhanced by a Subanesthetic Dose of Ketamine
Опубликована: Янв. 1, 2024
Язык: Английский
Individual differences in spatial working memory strategies differentially reflected in the engagement of control and default brain networks
Cerebral Cortex,
Год журнала:
2024,
Номер
34(8)
Опубликована: Авг. 1, 2024
Abstract
Spatial
locations
can
be
encoded
and
maintained
in
working
memory
using
different
representations
strategies.
Fine-grained
provide
detailed
stimulus
information,
but
are
cognitively
demanding
prone
to
inexactness.
The
uncertainty
fine-grained
compensated
by
the
use
of
coarse,
robust
categorical
representations.
In
this
study,
we
employed
an
individual
differences
approach
identify
brain
activity
correlates
spatial
memory.
We
combined
data
from
six
functional
magnetic
resonance
imaging
studies,
resulting
a
sample
$155$
($77$
women,
$25
\pm
5$
years)
healthy
participants
performing
task.
Our
results
showed
that
were
associated
with
distinct
patterns
activity.
Higher
precision
was
related
greater
engagement
attentional
control
systems
throughout
task
trial,
stronger
deactivation
default
network
at
time
encoding.
contrast,
lower
during
encoding
higher
frontoparietal
activation
maintenance.
These
may
indicate
need
for
resources
protection
against
interference
compared
Язык: Английский
Individual differences in spatial working memory strategies differentially reflected in the engagement of control and default brain networks
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2023,
Номер
unknown
Опубликована: Июль 7, 2023
Spatial
locations
can
be
encoded
and
maintained
in
working
memory
using
different
representations
strategies.
Fine-grained
provide
detailed
stimulus
information,
but
are
cognitively
demanding
prone
to
inexactness.
The
uncertainty
fine-grained
compensated
by
the
use
of
coarse,
robust
categorical
representations.
In
this
study,
we
employed
an
individual
differences
approach
identify
brain
activity
correlates
spatial
memory.
We
combined
data
from
six
fMRI
studies,
resulting
a
sample
155
(77
women,
25
±
5
years)
healthy
participants
performing
task.
Our
results
showed
that
were
associated
with
distinct
patterns
activity.
Higher
precision
was
related
greater
engagement
attentional
control
systems
throughout
task
trial,
stronger
deactivation
default
network
at
time
encoding.
contrast,
lower
during
encoding
higher
frontoparietal
activation
maintenance.
These
may
indicate
need
for
resources
protection
against
interference
compared
Язык: Английский