Defining Misinformation and Related Terms in Health-Related Literature: Scoping Review

Journal of Medical Internet Research, Год журнала: 2023, Номер 25, С. e45731 - e45731

Опубликована: Авг. 9, 2023

Misinformation poses a serious challenge to clinical and policy decision-making in the health field. The COVID-19 pandemic amplified interest misinformation related terms witnessed proliferation of definitions.

Язык: Английский

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Can Vaccines Stop Cancer Before It Starts? Assessing the Promise of Prophylactic Immunization Against High-Risk Preneoplastic Lesions

Journal of Cellular Immunology, Год журнала: 2023, Номер 5(4), С. 127 - 140

Опубликована: Ноя. 29, 2023

Background: Cancer remains a leading cause of mortality with modest declines, highlighting the need for more efficacious prevention strategies like early immunological intervention against premalignant disease. Main body abstract: Oncogenic viruses demonstrate prophylactic vaccines can successfully reduce malignancy by blocking precipitating infections. However, most cancers lack viral etiology, requiring novel approaches targeting sporadic precancerous states to enable immunoprevention. Preneoplastic tissues exhibit biological changes making them appealing targets stimulating immune surveillance before additional mutations unconstrained proliferation. High-risk precancers also provide sources dysregulated self-antigens. Yet challenges exist in lesion identification, overcoming tolerance, and avoiding inflammation potentially worsening progression. Multidisciplinary insights into precancer immunology, predictive biomarkers, antigen discovery, combinatorial vaccination are illuminating rational vaccine design. Despite obstacles, immunization dysplastic holds disruptive potential if key steps advance this approach. Elucidating preneoplasia immunobiology progression risk modeling will be critical guide productive while mitigating immunotherapy hazards. Thoughtful translation could eventually shift paradigms priming immunosurveillance peak vulnerability lesions. Short Conclusion: Advancements may profoundly expand horizons. Cautious intercept toward widely disseminated malignancies. This warrants methodical efforts unravel promise thwarting lethal they start.

Язык: Английский

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A review of HPV and HBV vaccine hesitancy, intention, and uptake in the era of social media and COVID-19

eLife, Год журнала: 2023, Номер 12

Опубликована: Авг. 18, 2023

Prior to the COVID-19 pandemic, World Health Organization named vaccine hesitancy as one of top 10 threats global health. The impact on uptake human papillomavirus (HPV) vaccines was particular concern, given markedly lower compared other adolescent in some countries, notably United States. With recent approval vaccines, coupled with widespread use social media, concerns regarding have grown. However, association between COVID-related and cancer such HPV is unclear. To examine potential association, we performed two reviews using Ovid Medline APA PsychInfo. Our aim answer questions: (1) Is hesitancy, intention, or associated hepatitis B (HBV) uptake? (2) exposure misinformation media HBV review identified few published empirical studies that addressed these questions. results highlight urgent need for can shift through vast quantities data better understand link disinformation its vaccines.

Язык: Английский

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Factors influencing hepatitis B vaccination intention and behavior among college students in Tibet: Insights from the expanded theory of planned behavior

Human Vaccines & Immunotherapeutics, Год журнала: 2025, Номер 21(1)

Опубликована: Янв. 16, 2025

Hepatitis B (Hep B) remains a critical public health issue globally, particularly in Tibet, where vaccination rates and influencing factors among college students are yet understudied. This study applies cross-sectional design to investigate the Hep rate 1,126 Tibet utilizes expanded theory of planned behavior (ETPB) identify intention (BI) (VB). Stratified cluster sampling across three universities was used assess behavioral attitudes (BA), subjective norms (SN), perceived control (PBC), past history (PVH) knowledge (VK), structural equation modeling (SEM) for model validation multi-group comparison. Results indicated that 16.3% had received vaccine. VK notably improved BA toward (β = 0.518, p < .001). 0.232, .001), PBC 0.239, SN 0.385, .001) positively influenced BI. However, PVH failed predict BI 0.448, 0.127, were significant predictors VB. Significant ethnic variations noted. The positive effect on VB 0.151, mediating role 0.076, .05) Tibetan students. stronger Tibetans 0.503, .05),while impact attitude more pronounced Han 0.366, .05). is relatively low, ETPB effectively explains their intentions behaviors. Tailored intervention strategies recommended boost effectively.

Язык: Английский

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Unraveling HPV-Associated cancer complexity: From molecular insights to innovative therapies

Heliyon, Год журнала: 2025, Номер 11(3), С. e42437 - e42437

Опубликована: Фев. 1, 2025

Язык: Английский

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Therapeutic Impact of Gardasil® in Recurrent Respiratory Papillomatosis: A Retrospective Study on RRP Patients

Viruses, Год журнала: 2025, Номер 17(3), С. 321 - 321

Опубликована: Фев. 26, 2025

Background: Recurrent respiratory papillomatosis (RRP) is a rare, non-malignant disease caused by human papillomavirus (HPV) types 6 and 11. The condition primarily affects the larynx, potentially leading to life-threatening airway obstruction. It more aggressive in younger patients, necessitating frequent surgical interventions. This study investigates therapeutic potential of prophylactic HPV vaccine Gardasil® RRP focusing on its impact lesion size frequency Furthermore, literature review was conducted analyze factors influencing decision vaccinate. Methods: A retrospective analysis 63 patients treated from 2008 2021. Disease burden assessed using Derkay score annual laser-surgical ablations. Comparisons were made between pre- post-vaccination periods vaccinated (n = 18), first second halves disease’s course unvaccinated 14). Results: reduction interventions (p < 0.05) could be seen. cumulated per year decreased after third vaccination 0.05). influenced multiple (e.g., side-effects, sociocultural factors, social media, pre-existing conditions wider context recent pandemic). Conclusions: appears reduce surgery lessen severity supporting role as option for RRP. Moreover, it crucial overcome skepticism towards vaccinations prevent development HPV-associated diseases place.

Язык: Английский

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Increasing confidence for pediatric COVID-19 and influenza vaccines using messages affirming parental autonomy: A randomized online experiment

Vaccine, Год журнала: 2025, Номер 53, С. 126947 - 126947

Опубликована: Март 2, 2025

Язык: Английский

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Factors influencing vaccine hesitancy among United Kingdom adolescents in a senior high school environment and actions to address it

Human Vaccines & Immunotherapeutics, Год журнала: 2025, Номер 21(1)

Опубликована: Март 11, 2025

We explored adolescent viewpoints on vaccines and hesitancy using an anonymized, validated, self-completed electronic questionnaire amongst state-school Year 12-13 adolescents in London, UK. As the response rate was low (Cohort 1; n = 112/486, 23.0%), we repeated survey with incoming students (cohort 2, 256/275; 93%). A focus group (n 31) evaluated international HPV campaign posters. Cohort 1 participants were 82.1% female, 13.4% male, ethnically diverse (32.1% Asian/Asian British, 29.5% Black/Black 25.9% White, 7.1% Mixed); 2 80% 18% identifying as 38% 34% 15% 12% Mixed/Others. Across both cohorts, believed childhood vaccinations safe 95.8%, 91%). COVID-19 vaccination uptake higher than (76.8% vs 67%), fewer believing it adequately tested (56.3% 47%). Support for mandatory healthcare workers (HCW) high 1:77.8-79% "all" "patient-facing HCWs;" 62-64%). Similar patterns observed influenza 1: 62.5-66.7%; 2: 62-63%). Vaccination decisions primarily influenced by parents (96%), providers (48%), school friends (36%) 30.2%, 19.6%, 12%, respectively). Recommendations doctors, experts (but not politicians) school-based vaccine availability boosted confidence. Social media had minimal impact. Most received 83.1%, 77.2%). International posters strong but mixed support; direct design input from target is needed to ensure success of visual promotions.

Язык: Английский

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Exploring barriers and potential strategies to improve HPV vaccine uptake: Perspectives of adolescents living with HIV and guardians in Lilongwe.

Research Square (Research Square), Год журнала: 2025, Номер unknown

Опубликована: Март 17, 2025

Background: Female Adolescents Infected with HIV are at higher risk for Human Papillomavirus -related cancers, making them a priority HPV vaccination. Increasing vaccination rates in this group is key to reducing cervical cancer incidence.The Global Action strategy eliminate requires achieving 90% national coverage and 80% district However, the uptake of vaccine Malawi has been slow, an less than 73%. This study explored facilitators barriers among female adolescents infected Lilongwe, Malawi. Methods: qualitative phenomenological employed two focus discussions 12 in-depth interviews HIV, healthcare workers caregivers respectively. Study participants were sampled from Mitundu Community Hospital Area 18 Urban Health Centre April 2022. through teen clubs. Thirty enrolled using quota sampling. Recorded transcribed verbatim translated into English analysis. The data analysed thematic approach. Results: negative attitudes towards misconceptions about due inadequate or incorrect information, lack adequate shortage vaccine. Strategies improving vaccines include raising awareness sensitization HPV, resource availability, advocating other delivery modes, such as integration HPV-related interventions clubs enhance uptake. Overall, club clinic days proposed best screen unvaccinated recommend Conclusion: Teen should be well positioned fill gap previously lost opportunities administration empower by endorsing Further research explore feasibility readiness administering clinics.

Язык: Английский

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Determinants of Human Papillomavirus Vaccine Acceptance among Caregivers in Nigeria: A Fogg Behavior Model-Based Approach

Vaccines, Год журнала: 2024, Номер 12(1), С. 84 - 84

Опубликована: Янв. 13, 2024

Human papillomavirus (HPV) vaccine uptake among adolescent girls is critical to reducing the burden of HPV-related cancers in Nigeria. This study assesses factors influencing caregivers’ acceptance HPV vaccination for their charges, using Fogg Behavior Model (FBM) as a theoretical framework. We analyzed cross-sectional data from 1429 caregivers aged 9–17 six Nigerian states, survey instrument based on FBM. Participants were recruited via Facebook and Instagram advertisements interviewed through Messenger August September 2023. The received ethical clearance Nigeria’s National Health Research Ethics Committee. applied bivariate multivariate analyses assess relationships between caregiver’s perception how likely girl was get vaccinated next 12 months motivation, ability, social (such discussions with family friends), injunctive norms, previous COVID-19 vaccination, respondents’ sociodemographic characteristics. Adjusted odds ratios derived logistic regression revealed that motivation well factors, significantly associated care would within months. Our findings suggest behavioral interventions tailored enhance support could increase

Язык: Английский

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