Fundamental processes in sensorimotor learning: Reasoning, refinement, and retrieval

eLife, Год журнала: 2024, Номер 13

Опубликована: Авг. 1, 2024

Motor learning is often viewed as a unitary process that operates outside of conscious awareness. This perspective has led to the development sophisticated models designed elucidate mechanisms implicit sensorimotor learning. In this review, we argue for broader perspective, emphasizing contribution explicit strategies tasks. Furthermore, propose theoretical framework motor consists three fundamental processes: reasoning, understanding action–outcome relationships; refinement, optimizing and cognitive parameters achieve goals; retrieval, inferring context recalling control policy. We anticipate ‘3R’ how complex movements are learned will open exciting avenues future research at intersection between cognition action.

Язык: Английский

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Fundamental processes in sensorimotor learning: Reasoning, Refinement, and Retrieval

Опубликована: Авг. 2, 2023

[Now published in eLife: https://elifesciences.org/articles/91839] Motor learning is often viewed as a unitary process that operates outside of conscious awareness. This perspective has led to the development sophisticated models designed elucidate mechanisms implicit sensorimotor learning. In this review we argue for broader perspective, emphasizing contribution explicit strategies tasks. Furthermore, propose theoretical framework motor consists three fundamental processes: Reasoning, understanding action-outcome relationships; Refinement, optimizing and cognitive parameters achieve goals; Retrieval, inferring context recalling control policy. We anticipate “3R” how complex movements are learned will open exciting avenues future research at intersection between cognition action.

Язык: Английский

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Reconfigurations of cortical manifold structure during reward-based motor learning

eLife, Год журнала: 2023, Номер 12

Опубликована: Ноя. 9, 2023

Adaptive motor behavior depends on the coordinated activity of multiple neural systems distributed across brain. While role sensorimotor cortex in learning has been well established, how higher-order brain interact with to guide is less understood. Using functional MRI, we examined human during a reward-based task where subjects learned shape their hand trajectories through reinforcement feedback. We projected patterns cortical and striatal connectivity onto low-dimensional manifold space regions expanded contracted along learning. During early learning, found that several areas dorsal attention network exhibited increased covariance salience/ventral reduced default mode (DMN). late these effects reversed, now exhibiting DMN areas. However, posteromedial showed opposite pattern phases, its suggesting coordinating different networks over time. Our results establish changes support identify distinct transitions coupling transmodal when adapting behavior.

Язык: Английский

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Changes in cortical manifold structure following stroke and its relation to behavioral recovery in the male macaque

Nature Communications, Год журнала: 2024, Номер 15(1)

Опубликована: Окт. 18, 2024

Stroke, a major cause of disability, disrupts brain function and motor skills. Previous research has mainly focused on reorganization the system post-stroke, but effects other areas their influence recovery is poorly understood. Here, we use functional neuroimaging in nonhuman primate model (23 male Cynomolgus Macaques), explore how ischemic stroke affects whole-brain cortical architecture its relation to spontaneous behavioral recovery. By projecting patterns connectivity onto low-dimensional manifold space, find that several regions both sensorimotor cortex higher-order transmodal exhibit significant shifts embedding from pre- post-stroke. Furthermore, observe changes default mode limbic network regions, not preserved are associated with animal These results establish stroke, suggest an important role for post-stroke outcomes. Using advanced imaging macaques, authors show such as those involved emotion cognition, after which linked better

Язык: Английский

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