Frontiers in Physiology,
Год журнала:
2022,
Номер
12
Опубликована: Янв. 13, 2022
An
organism’s
diet
is
a
major
route
of
exposure
to
both
beneficial
nutrients
and
toxic
environmental
chemicals
natural
products.
The
uptake
dietary
xenobiotics
in
the
intestine
prevented
by
transporters
Solute
Carrier
(SLC)
ATP
Binding
Cassette
(ABC)
family.
Several
toxins
have
been
identified
induce
expression
these
defense
fish
aquatic
invertebrates,
indicating
that
they
are
substrates
can
be
eliminated.
However,
certain
chemicals,
termed
Transporter-Interfering
Chemicals
or
TICs,
recently
shown
bind
inhibit
mammalian
P-glycoprotein
(ABCB1),
thereby
sensitizing
cells
chemical
accumulation.
If
what
extent
other
xenobiotic
nutrient
also
inhibited
TICs
still
unknown.
To
date,
most
chemical-transporter
interaction
studies
organisms
focused
on
ABC-type
transporters,
while
molecular
interactions
with
SLC-type
poorly
understood.
In
this
perspective,
we
summarize
current
advances
identification,
localization,
functional
analysis
protective
MXR
systems
digestive
system
invertebrates.
We
collate
existing
literature
data
chemically
induced
transporter
gene
transport
systems.
Our
review
emphasizes
need
for
standardized
assays
broader
panel
commercially
important
seafood
species
better
evaluate
effects
TIC
physiological
across
ecosystem
predict
possible
transfer
humans
through
consumption.
San Francisco Estuary and Watershed Science,
Год журнала:
2019,
Номер
17(4)
Опубликована: Дек. 8, 2019
Legacy
and
current-use
contaminants
enter
into
accumulate
throughout
the
San
Francisco
Bay−Delta
(Bay−Delta),
are
present
at
concentrations
with
known
effects
on
species
important
to
this
diverse
watershed.
There
remains
major
uncertainty
a
lack
of
focused
research
able
address
provide
understanding
across
multiple
biological
scales,
despite
previous
ongoing
emphasis
need
for
it.
These
needs
challenging
specifically
because
established
regulatory
programs
that
often
monitor
chemical-by-chemical
basis,
or
in
which
decisions
grounded
lethality-based
endpoints.
To
best
issues
Bay−Delta,
monitoring
efforts
should
consider
environmentally
relevant
mixtures
sub-lethal
impacts
can
affect
ecosystem
health.
complex
environment
including
variable
abiotic
(e.g.,
temperature,
salinity)
biotic
pathogens)
factors.
This
calls
controlled
research,
development
multi-disciplinary
contaminant
assessment
program
provides
information
scales.
Information
gained
manner
will
contribute
toward
evaluating
parameters
could
alleviate
ecologically
detrimental
outcomes.
review
is
result
Special
Symposium
convened
University
California−Davis
(UCD)
January
31,
2017
critical
needed
how
Bay−Delta.
The
UCD
new
tools
approaches
assessing
stressor
freshwater
estuarine
systems.
Our
approach
similar
recently
proposed
framework
laid
out
by
U.S.
Environmental
Protection
Agency
(USEPA)
uses
weight
evidence
scale
toxicological
responses
chemical
laboratory,
guide
conservation
priority
habitats.
As
such,
we
also
aimed
recommend
endpoints
be
used
promote
risks
while
supporting
management
needs.
Journal of the American Mosquito Control Association,
Год журнала:
2024,
Номер
40(1), С. 26 - 31
Опубликована: Фев. 19, 2024
ABSTRACT
Understanding
the
influence
of
salinity
on
efficacy
mosquito
larvicides
in
brackish
water
habitats
is
crucial
for
effective
salt-marsh
Aedes
taeniorhynchus
control.
This
study
investigated
interactive
effects
toxicity
3
commonly
used
larvicides:
Bacillus
thuringiensis
israelensis
(VectoBac®
12AS),
spinosad
(Natular®
SC),
and
S-methoprene
(Altosid®
12AS)
against
Ae.
larvae.
Four
levels
(0
ppt
[parts
per
thousand],
8
ppt,
16
32
ppt)
were
tested
laboratory
bioassays.
The
results
revealed
distinct
responses
these
to
varying
levels.
VectoBac
12AS
displayed
consistent
across
all
levels,
indicating
its
suitability
habitats.
In
contrast,
Natular
2EC
exhibited
increased
effectiveness
with
higher
salinity,
making
it
a
preferable
choice
saline
environments.
Altosid
showed
highest
freshwater,
reduced
as
increased.
These
findings
underscore
need
consider
when
selecting
applying
diverse
aquatic
complex
interplay
between
larvicide
performance
essential
optimizing
control
strategies
mitigating
mosquito-borne
diseases
various
