MODERN METHODS OF DIAGNOSIS AND TREATMENT OF CHRONIC ENDOMETRITIS, IN PREPARING PATIENTS FOR ASSISTED REPRODUCTIVE TREATMENT TECHNOLOGIES (LIT ERATURE REVIEW)

REPORTS, Год журнала: 2020, Номер 2(330), С. 21 - 28

Опубликована: Апрель 15, 2020

Since the chronic endometritis often leads to impaired reproductive function causing infertility, failed IVF attempts, miscarriage, and complicated pregnancy childbirth, it has become not only medically relevant but also socially significant. For successful embryo implantation, thickness of endometrium should be at least 7 cm. Even though there is always a chance for despite endometrial hypoplasia, attachment may fragile, such cease its development further on. Recently, in connection with an increase rate developing allergic reactions, dysbacteriosis, emergence drug-resistant strains microorganisms, search new treatment methods avoid these complications begun. One treating endometritis, satisfying several requirements (efficiency, comfort, accessibility, safety), ultrasonic cavitation uterine cavity.

Язык: Английский

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Research of systemic immunity and hemostasis in women with pathological processes of the epithelium of the genitals with atypia of cells of unclear genesis in women with infertility

Reproductive Endocrinology, Год журнала: 2020, Номер 52, С. 24 - 27

Опубликована: Май 13, 2020

Purpose of the study: to study systemic immunity and hemostasis in women with infertility pathological processes glandular epithelium genitals atypical cells not otherwise specified.Materials methods. The included 173 specified (main group). comparison group consisted 100 without cervical epithelium. All patients underwent studies immune systems (population lymphocytes, circulating complexes) (screening coagulation tests, number aggregation function platelets).Results. Analysis system revealed certain changes main group, more pronounced endometrial pathology - inhibition cell link (evidenced by a decrease absolute relative CD3+ T value, CD4+, CD16 phagocytic number) against background humoral activation (increase CD22+ level, complexes, IgG IgA). vascular-platelet showed platelets tendency an increase platelet anisocytosis counts pathology. An analysis significant adenosine diphosphate, adrenaline collagen pathology, also hypercoagulation.Conclusions. In there is suppression cellular hyperactivation. Activation vascular–platelet hypercoagulative state were revealed.

Язык: Английский

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POSSIBILITIES OF THE USE OF INTRAUTERINE CONTRACEPTION IN WOMEN OF DIFFERENT AGE GROUPS

Medical & pharmaceutical journal Pulse, Год журнала: 2020, Номер unknown, С. 24 - 28

Опубликована: Окт. 19, 2020

Currently, the problem of family planning is not only medical, but also social. The reason for this widespread use artificial termination pregnancy in our country. Moreover, majority women Russia resort to extremely dangerous method abortion - acute curettage, which associated with a high risk further infertility and development long-term adverse consequences. It necessary inform all patients reproductive age about neg-ative consequences preg-nancy possibilities modern methods con-traception. One most popular country (in second place after combined oral contraceptives) highly effective (Pearl index 0.1-0.5) contraception intrauterine device. Intrauterine systems (IUDs) are reversible contraception, makes them easy affordable. IUD installed 5 years does require constant monitoring by patient. If necessary, device can be removed at any time. Another positive aspect that fertility restored 12 months 80-96% cas-es. Also, contraceptives have thera-peutic effect, since local action allows you nor-malize menstrual cycle, especially im-portant suffering from hyperpolymenor-rhea chronic anemia. has been proven IUDs do increase developing endome-trial cervical malignant tumors and, addition, antiproliferative antimitotic effects, it possible complex atypical hyperplasia differentiated stage IA endometrial adenocarcinoma.

Язык: Английский

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Management of infertile patients with chronic endometritis

Meditsinskiy sovet = Medical Council, Год журнала: 2022, Номер 16, С. 67 - 72

Опубликована: Окт. 8, 2022

Introduction. Chronic endometritis complicates infertility management that sets the task of searching new approaches treatment. Special attention is paid to use enzymatic drugs improve repair processes. Аim. Тo evaluate effect bovgialuronidasa azoxymer on restoration morphofunctional state endometrium and receptor apparatus in infertile women with chronic endometritis. Materials methods. Forty-seven reproductive age who applied for were examined. The general, somatic, gynecological history assessment has been carried out. Complaints included pain syndrome (100 %), discharge from genital tract during palpation uterine traction (89.4 %). Paipel-biopsy was out subsequent morphological cultural study endometrium. immunohistochemical analysis out, endometrial receptivity studied. middle M-echo detected. Statistical processing using Microsoft Exel application package (2010), STATISTICA 13.3 (USA, Tibco). Results. Diagnostic measures including examination allows verify this protocol half achieve pregnancy. increases rate pregnancy 23.9 %. Conclusion. Treatment under patients due endometritis, autoimmune one,

Язык: Английский

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