Abstract
Microfluidic
devices
have
become
a
vastly
popular
technology,
particularly
because
of
the
advantages
they
offer
over
their
traditional
counterparts.
They
such
wide
range
uses
and
can
make
complex
tasks
quite
efficient.
One
area
research
or
work
that
has
benefited
greatly
from
use
microfluidics
is
biosensing,
where
microfluidic
chips
are
integrated
into
biosensor
setups.
There
growing
numbers
applications
in
this
as
researchers
look
for
efficient
ways
to
tackle
disease
diagnostics
drug
discovery,
which
critical
era
recurring
pandemics.
In
work,
authors
review
integration
with
biosensors,
well
food
security,
molecular
biology,
cell
diagnostics,
at
some
most
recent
these
areas.
The
covers
including
cellular
life
science
research,
agro-food
processing,
immunological
veterinarian
diagnostics.
Microfluidics
field
combines
fundamental
laws
physics
chemistry
solve
miniaturization
problems
involving
fluids
nanoscale
microscale,
such,
also
examine
mathematical
concepts
biosensing.
relatively
new
technologies
great
potential
terms
applications.
Molecules,
Год журнала:
2023,
Номер
28(18), С. 6624 - 6624
Опубликована: Сен. 14, 2023
Knowing
the
beneficial
aspects
of
nanomedicine,
scientists
are
trying
to
harness
applications
nanotechnology
in
diagnosis,
treatment,
and
prevention
diseases.
There
also
potential
uses
designing
medical
tools
processes
for
new
generation
scientists.
The
main
objective
conducting
this
research
review
is
gather
widespread
nanomedicine
under
one
heading
highlight
standard
practices
field.
Comprehensive
has
been
conducted
incorporate
latest
data
related
medicine
therapeutics
derived
from
acknowledged
scientific
platforms.
Nanotechnology
used
conduct
sensitive
procedures.
showing
successful
fields
diagnostics,
disease
regenerative
medicine,
gene
therapy,
dentistry,
oncology,
aesthetics
industry,
drug
delivery,
therapeutics.
A
thorough
association
cooperation
between
physicians,
clinicians,
researchers,
technologies
will
bring
forward
a
future
where
there
more
calculated,
outlined,
technically
programed
field
nanomedicine.
Advances
being
made
overcome
challenges
associated
with
application
due
pathophysiological
basis
This
highlights
multipronged
how
proving
health
industry.
need
minimize
health,
environmental,
ethical
concerns
linked
nanotechnology.
Biosensors,
Год журнала:
2022,
Номер
13(1), С. 40 - 40
Опубликована: Дек. 27, 2022
Biosensors
are
modern
engineering
tools
that
can
be
widely
used
for
various
technological
applications.
In
the
recent
past,
biosensors
have
been
in
a
broad
application
spectrum
including
industrial
process
control,
military,
environmental
monitoring,
health
care,
microbiology,
and
food
quality
control.
also
specifically
monitoring
pollution,
detecting
toxic
elements’
presence,
presence
of
bio-hazardous
viruses
or
bacteria
organic
matter,
biomolecule
detection
clinical
diagnostics.
Moreover,
deep
medical
applications
such
as
well-being
chronic
disease
treatment,
vitro
examination
studies
screening
infectious
diseases
early
detection.
The
scope
expanding
use
is
very
high
owing
to
their
inherent
advantages
ease
use,
scalability,
simple
manufacturing
process.
Biosensor
technology
more
prevalent
large-scale,
low
cost,
enhanced
field.
Integration
nanotechnology
with
has
shown
development
path
novel
sensing
mechanisms
they
enhance
performance
ability
currently
biosensors.
Nanoscale
dimensional
integration
promotes
formulation
rapid
molecules
along
single
biomolecules
where
evaluated
analyzed
critically.
Nanomaterials
nano-biosensors
nanomaterials
commonly
include
nanoparticles,
nanowires,
carbon
nanotubes
(CNTs),
nanorods,
quantum
dots
(QDs).
possess
color
tunability,
sensitivity,
large
surface
area,
carrier
capacity,
stability,
thermal
electrical
conductivity.
current
review
focuses
on
nanotechnology-enabled
biosensors,
fundamentals,
architectural
design.
expands
view
materials
fabricating
probable
The
methodological
advancements
in
surface-enhanced
Raman
scattering
(SERS)
technique
with
nanoscale
materials
based
on
noble
metals,
Au,
Ag,
and
their
bimetallic
alloy
Au-Ag,
has
enabled
the
highly
efficient
sensing
of
chemical
biological
molecules
at
very
low
concentration
values.
By
employing
innovative
various
type
Ag
nanoparticles
especially,
high
efficiency
Au@Ag
nanomaterials
as
substrate
SERS
biosensors
have
revolutionized
detection
components
including;
proteins,
antigens
antibodies
complex,
circulating
tumor
cells,
DNA,
RNA
(miRNA),
etc.
This
review
is
about
SERS-based
Au/Ag
enhanced
activity
by
focusing
different
factors
related
to
them.
emphasis
this
research
describe
recent
developments
field
conceptual
behind
Furthermore,
article
we
apex
understanding
impact
variation
basic
features
like
effects
size,
shape
varying
lengths,
thickness
core-shell
influence
large-scale
magnitude
morphology.
Moreover,
detailed
information
applications
these
importantly
receptor
binding
domain
(RBD)
protein
COVID-19
provided.
Biosensors and Bioelectronics X,
Год журнала:
2022,
Номер
12, С. 100284 - 100284
Опубликована: Ноя. 25, 2022
The
recent
COVID-19
infection
outbreak
has
raised
the
demand
for
rapid,
highly
sensitive
POC
biosensing
technology
intelligent
health
and
wellness.
In
this
direction,
efforts
are
being
made
to
explore
high-performance
nano-systems
developing
novel
sensing
technologies
capable
of
functioning
at
point-of-care
(POC)
applications
quick
diagnosis,
data
acquisition,
disease
management.
A
combination
nanostructures
[i.e.,
0D
(nanoparticles
&
quantum
dots),
1D
(nanorods,
nanofibers,
nanopillars,
nanowires),
2D
(nanosheets,
nanoplates,
nanopores)
3D
nanomaterials
(nanocomposites
complex
hierarchical
structures)],
prototype,
micro-electronics
makes
suitable
early
detection
prevention
life-threatening
diseases.
However,
a
knowledge
gap
associated
with
potential
0D,
1D,
2D,
design
development
efficient
is
yet
be
explored
carefully
critically.
With
focus,
review
highlights
latest
engineered
next-generation
miniaturized,
portable
biosensors
achieve
high
sensitivity
integration
internet
medical
things
(IoMT,
miniaturization
collection,
security,
sharing),
artificial
intelligence
(AI,
desired
analytics),
etc.
better
diagnosis
management
personalized
level.
Biosensors,
Год журнала:
2023,
Номер
13(3), С. 411 - 411
Опубликована: Март 22, 2023
One
of
the
emerging
technologies
in
molecular
diagnostics
last
two
decades
is
use
gold
nanoparticles
(AuNPs)
for
biosensors.
AuNPs
can
be
functionalized
with
various
biomolecules,
such
as
nucleic
acids
or
antibodies,
to
recognize
and
bind
specific
targets.
present
unique
optical
properties,
their
distinctive
plasmonic
band,
which
confers
a
bright-red
color
AuNP
solutions,
extremely
high
extinction
coefficient,
makes
detectable
by
naked
eye
even
at
low
concentrations.
Ingenious
mechanisms
triggered
presence
target
analyte
change
colloidal
status
from
dispersed
aggregated,
subsequent
visible
solution
due
loss
characteristic
band.
This
review
describes
how
properties
have
been
exploited
design
biosensors
that
only
require
simple
mixing
reagents
combined
visual
readout
focuses
on
involved.
illustrates
selected
examples
AuNP-based
promising
approaches
point-of-care
testing
analytes,
spanning
viral
RNA
SARS-CoV-2
molecules
give
flavor
aged
whisky.
Journal of Science Advanced Materials and Devices,
Год журнала:
2024,
Номер
9(2), С. 100694 - 100694
Опубликована: Март 2, 2024
Nanomaterial
technology
is
a
comprehensive
subject
with
strong
intersections,
and
its
related
research
content
involves
wide
range
of
modern
scientific
technological
fields.
The
science
in
the
area
nanomaterials
has
attracted
attention
many
groups
over
past
few
years.
By
very
nature,
this
topic
lot
room
for
research,
to
tiny
objects
nanometer
range.
Nanomaterials
refer
sudden
changes
properties
substances
when
they
reach
scale,
resulting
special
properties.
In
paper,
we
introduce
various
commonly
used
field
biosensing,
briefly
explain
advantages
disadvantages
nanoscale
biosensors.
At
same
time,
also
working
principles
types
biosensors
based
on
nanomaterial
technology,
including
electrochemical
biosensors,
optical
piezoelectric
addition,
sensing
targets
common
such
as
enzymes,
DNA,
microorganisms,
etc.
Finally,
discuss
challenges
prospects
application
analyze
current
trends
future
directions.