ACS Applied Bio Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 27, 2025
Piezoelectricity
is
reported
to
be
able
promote
bone
scaffolds
with
excellent
osteogenic
performance.
Herein,
barium
titanate/β-tricalcium
phosphate
(BTO/β-TCP)
piezoelectric
composite
were
3D
printed,
and
their
performances
investigated
in
detail.
The
fabrication
of
BTO/β-TCP
employed
cutting-edge
DLP
printing
technology.
scaffolds,
featuring
a
triply
periodic
minimal
surface
(TPMS)
design
porosity
60%,
offered
unique
structural
framework.
A
comprehensive
assessment
the
composition,
properties,
mechanical
characteristics
was
conducted.
Notably,
an
increase
BTO
volume
fraction
from
50
80
vol
%
within
led
reduction
compressive
strength,
decreasing
2.47
1.74
MPa.
However,
this
variation
accompanied
by
substantial
enhancement
constant
d33,
soaring
1.4
pC/N
21.6
pC/N.
Utilizing
mouse
osteoblasts
(MC3T3-E1)
live/dead
cell
staining
assay,
under
influence
external
ultrasound,
demonstrated
commendable
biocompatibility
these
ceramic
scaffolds.
Furthermore,
thorough
analyses
alkaline
phosphatase
(ALP)
activity
polymerase
chain
reaction
(PCR)
findings
provided
compelling
evidence
scaffolds'
superior
underpinning
effectiveness
at
cellular
protein
gene
levels.
In
conclusion,
study
offers
groundbreaking
strategy
for
employment
implant
applications,
harnessing
blend
biocompatibility,
piezoelectricity,
potential.
Materials Today Chemistry,
Год журнала:
2024,
Номер
37, С. 102016 - 102016
Опубликована: Апрель 1, 2024
Tissue-engineered
constructs
can
replicate
the
structural
and
physiological
properties
of
natural
tissues.
The
be
designed
to
address
transplantation
issues
affected
by
shortage
donor
tissues
organs.
One
major
concerns
in
tissue
engineering
is
design
development
structures
that
improve
interaction
between
materials
cells
provide
an
ideal
platform
for
form
functional
tissue.
Several
contributing
factors
need
considered
fabricate
constructs,
including
biomaterials,
biological,
topographical,
biophysical,
morphological
either
alone
or
combination.
Here,
we
review
application,
advancement,
future
directions
these
essential
designing
developing
regeneration.
In
particular,
focus
on
original
approaches
tools
construct
parameters
engineering.
ACS Applied Bio Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 27, 2025
Piezoelectricity
is
reported
to
be
able
promote
bone
scaffolds
with
excellent
osteogenic
performance.
Herein,
barium
titanate/β-tricalcium
phosphate
(BTO/β-TCP)
piezoelectric
composite
were
3D
printed,
and
their
performances
investigated
in
detail.
The
fabrication
of
BTO/β-TCP
employed
cutting-edge
DLP
printing
technology.
scaffolds,
featuring
a
triply
periodic
minimal
surface
(TPMS)
design
porosity
60%,
offered
unique
structural
framework.
A
comprehensive
assessment
the
composition,
properties,
mechanical
characteristics
was
conducted.
Notably,
an
increase
BTO
volume
fraction
from
50
80
vol
%
within
led
reduction
compressive
strength,
decreasing
2.47
1.74
MPa.
However,
this
variation
accompanied
by
substantial
enhancement
constant
d33,
soaring
1.4
pC/N
21.6
pC/N.
Utilizing
mouse
osteoblasts
(MC3T3-E1)
live/dead
cell
staining
assay,
under
influence
external
ultrasound,
demonstrated
commendable
biocompatibility
these
ceramic
scaffolds.
Furthermore,
thorough
analyses
alkaline
phosphatase
(ALP)
activity
polymerase
chain
reaction
(PCR)
findings
provided
compelling
evidence
scaffolds'
superior
underpinning
effectiveness
at
cellular
protein
gene
levels.
In
conclusion,
study
offers
groundbreaking
strategy
for
employment
implant
applications,
harnessing
blend
biocompatibility,
piezoelectricity,
potential.
