Advanced Healthcare Materials,
Год журнала:
2024,
Номер
13(13)
Опубликована: Фев. 9, 2024
Aggregation-induced
emission
luminogens
(AIEgens)
are
promising
photosensitizers
that
have
exhibited
excellent
antibacterial
ability
with
abundant
reactive
oxygen
species
(ROS)
generation.
TTCPy-PF6
and
TTCPy-Br
deposited
on
the
surface
of
diverse
solid
substrates
through
plasma-assistant
electrostatic
self-assembly.
The
AIEgens-covered
coating
can
effectively
eliminate
different
pathogenic
Gram-positive
(G+)
bacteria
even
their
multidrug-resistant
(MDR)
mutants
negligible
side
effects
such
as
cytotoxicity,
hemolysis,
inflammation.
Moreover,
AIEgen-coated
maintain
high
stability
for
long-time
usage,
which
is
dependent
ROS-mediated
disruption
attached
bacteria.
AIEgen-based
coatings
broad
applicability
many
advantages
in
ability,
great
biocompatibility,
low
possibility
antibiotic
pollution.
robust
biological
safety
would
be
helpful
disinfection
medical
devices.
Advanced Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 9, 2024
Abstract
Bacteria
share
a
longstanding
and
complex
relationship
with
humans,
playing
role
in
protecting
gut
health
sustaining
the
ecosystem
to
cause
infectious
diseases
antibiotic
resistance.
Luminogenic
materials
that
aggregation‐induced
emission
(AIE)
characteristics
have
emerged
as
versatile
toolbox
for
bacterial
studies
through
fluorescence
visualization.
Numerous
research
efforts
highlight
superiority
of
AIE
this
field.
Recent
advances
are
categorized
into
four
areas:
understanding
interactions,
antibacterial
strategies,
diverse
applications,
synergistic
applications
bacteria.
Initial
focuses
on
visualizing
unseen
bacteria
progresses
developing
strategies
involving
electrostatic
amphiphilic
luminogens
(AIEgens),
various
enhance
affinity.
progress
includes
using
photodynamic
photothermal
therapies,
toxicity
studies,
combined
therapies.
Diverse
from
environmental
disinfection
disease
treatment,
utilizing
coatings,
sensors,
wound
healing
materials,
etc.,
also
provided.
Finally,
combining
achieve
enhanced
outcomes
explored.
This
review
summarizes
developmental
trend
is
expected
provide
future
directions
advancing
methodologies.
Advanced Functional Materials,
Год журнала:
2024,
Номер
34(26)
Опубликована: Фев. 26, 2024
Abstract
The
development
of
stable
Janus
architectures
suitable
for
biphasic
applications
holds
significant
importance.
A
novel
approach
is
introduced
interfacial
supramolecular
self‐assembly,
resulting
in
2D
nanosheets
(OA‐TA/Fe)
exhibiting
an
amphiphilic
nature.
These
consist
hydrophilic
coordination
complexes
ferric
ions
(Fe
3+
)
and
tannic
acid
(TA)
on
one
side
both
surfaces
hydrophobic
alkyl
chains
the
other
surfaces.
synthesis
these
involves
a
simple,
ultrafast,
environmentally
benign
process,
eliminating
need
time‐consuming
multistep
procedures
harsh
synthetic
conditions
typically
associated
with
architecture
formation.
By
exploiting
inherent
singular
anisotropic
wettability
OA‐TA/Fe‐2,
efficacy
innovative
efficient
separation
various
organic
liquid‐in‐water
water‐in‐organic
liquid
emulsions
elucidated.
Subsequent
post‐modification
OA‐TA/Fe
has
facilitated
highly
remediation
contaminated
oily
wastewater,
serving
as
model
catalysis
reaction,
wherein
function
simultaneously
emulsifiers
catalysts
within
mixtures.
methodology
establishes
rapid
self‐assembly
creation
free‐standing
nanosheets,
offering
compelling
prospects
their
application
diverse
fields,
exemplified
by,
but
not
limited
to,
case
studies
presented
herein.
Advanced Healthcare Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 8, 2025
Abstract
Poor
diabetic
wound
healing
poses
a
critical
threat
to
human
health.
Excessive
oxidative
stress
and
increased
susceptibility
bacterial
infection
are
key
issues
that
impede
healing.
Cerium
oxide
nanoparticles
(CeO
2
NPs)
have
attracted
increasing
attention
because
of
their
unique
antioxidant
antimicrobial
properties.
Here,
this
work
designs
near‐infrared
(NIR)
light‐responsive
gelatin
methacryloyl
(GelMA)/CeO
/polydopamine
(PDA)
hydrogel
with
antibacterial
effects.
The
exhibits
stable,
efficient,
controllable
photothermal
conversion
capacity
under
NIR
stimulation.
can
be
used
construct
local
microenvironment
conducive
chronic
Significant
effects
the
NIR‐responsive
GelMA/CeO
/PDA
on
both
Escherichia
coli
(E.coli)
methicillin‐resistant
Staphylococcus
aureus
(MRSA)
demonstrated
by
counting
colony‐forming
units
(CFUs)
in
live/dead
staining
experiments.
strong
activity
hydrogels
is
measuring
level
reactive
oxygen
species
(ROS).
effect
terms
promoting
validated
full‐thickness
cutaneous
wounds
rat
models.
Additionally,
describes
mechanism
which
promotes
healing;
inhibits
interleukin
(IL)‐17
signaling
pathway.
This
NIR‐responsive,
multifunctional
dressing
provides
targeted
approach