Advanced Functional Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 13, 2024
Abstract
Severe
skin
wounds
arising
from
burns,
cancers,
and
accidents
can
damage
the
entire
tissue
structure,
resulting
in
permanent
somatosensory
dysfunction
patients.
Although
emerging
hydrogel
dressings
have
shown
clinical
potential
for
accelerating
wound
repair,
use
of
an
individual
material
to
synchronously
restore
structure
sensory
function
defective
remains
a
challenge.
Herein,
multifunctional
that
combines
electroconductive
polydopamine‐capped
graphene
nanosheets
(PrGOs)
embedded
dynamically
crosslinked
dual‐polysaccharide
(xyloglucan
chitosan)
matrix
network
is
presented.
The
fabricated
hydrogels
adjustable
modulus
be
matched
at
site,
owing
dynamic
Schiff‐based
crosslinking
as
well
facile
photo‐triggered
secondary
crosslinking.
Furthermore,
photothermal
activity
PrGO
elevate
local
temperature
up
≈50
°C,
significantly
restraining
bacterial
growth.
These
two
factors
jointly
promote
regeneration
tissue.
Tissue
adhesion
also
reported
offers
conformable
robust
interface
detect
quantify
human
movement
physiological
signals
mimic
system.
This
effective
one‐stone‐for‐two‐birds
simultaneously
achieves
multi‐signal
sensing,
promoting
restoration
and/or
replacement
damaged
skins.
Chemical Society Reviews,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
This
tutorial
review
presents
the
development
of
advanced
immunomodulatory
hydrogels
strategically
designed
to
address
chronic
inflammation
through
their
intrinsic
properties.
Advanced Functional Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 3, 2025
Abstract
The
application
of
these
NIPAm‐based
temperature‐sensitive
hydrogels
in
wearable
sensing
is
limited
by
the
inability
to
achieve
a
long‐lasting
temperature
response
and
adaptive
optical
regulation
due
water
loss
hydrogel,
avoid
phenomenon
detachment
external
touch,
mutual
interference
between
stress
signals.
Here,
sandwich‐structured
organogel
sensors
(SOGS)
are
prepared
based
on
solvent
modulation
interfacial
fusion
cross‐linking
strategies
asymmetric‐adhesion,
regulation,
simultaneous
human
motion
without
Modulation
properties
through
hydrogen
bonding
glycol
amide
groups
for
long‐term
(10–30
°C)
infrared
ultraviolet
regulation.
Adhesive
conductive
introduced
under
an
strategy
unilateral
adhesion
(67.28
kPa
pig
skin)
sensing.
intermediate
layer
prevents
In
conclusion,
provides
new
idea
developing
novel
responsive
gels,
facile
method
unilaterally
adherent,
interference‐resistant,
multifunctional
sensors.
Advances in Polymer Technology,
Год журнала:
2024,
Номер
2024(1)
Опубликована: Янв. 1, 2024
Poly(N‐isopropylacrylamide)
(PNIPAM)
is
a
versatile
polymer
known
for
its
phase
transition
properties,
exhibiting
lower
critical
solution
temperature
(LCST)
of
approximately
32°C.
Below
this
temperature,
PNIPAM
hydrophilic,
while
above
it,
the
becomes
hydrophobic,
making
it
ideal
thermosensitive
drug
delivery
systems
(DDSs).
In
tissue
engineering,
provides
biocompatible,
nontoxic
and
stimuli‐responsive
surface
cell
culture.
Its
nature
ensures
safety
in
medical
applications.
enhances
biosensing
diagnostics
through
affinity
biomolecules,
improving
accuracy.
Widely
used
hydrogels,
smart
textiles,
soft
robotics
various
applications,
adapts
to
environmental
changes.
straightforward
synthesis
allows
creation
diverse
copolymers
composites,
applicable
selective
reactions
conjugations
with
fluorescent
tags
or
chemical
modifications.
PNIPAM’s
versatility
extends
pH‐responsive
alternatives,
broadening
application
spectrum.
Practical
examples
include
separation
water
treatment
cleaning
processes.
This
discussion
explores
biomedical
particularly
cancer
treatment,
photothermal
therapy
(PTT)
photodynamic
(PDT),
gene
imaging.
Additionally,
highlights
noncancerous
such
as
small
interfering
RNA
(siRNA)
targeting
oncogenes
detailed
imaging
deep
tumour
tissues.
Chemical Communications,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
This
review
discusses
design
strategies
for
external
stimuli-driven
hydrogels
with
in
situ
catalytic
processes.
It
highlights
precise
control
over
the
properties,
elucidating
regulatory
mechanisms
and
deepening
understanding
of
applications.
Biomacromolecules,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 17, 2025
The
skin
is
fragile,
making
it
very
vulnerable
to
damage
and
injury.
Untreated
wounds
can
pose
a
serious
threat
human
health.
Three-dimensional
polymer
network
hydrogels
have
broad
application
prospects
in
wound
dressings
due
their
unique
properties
structure.
therapeutic
effect
of
traditional
limited,
while
multifunctional
composite
show
greater
potential.
Multifunctional
regulate
moisture
through
formula
adjustment.
Moreover,
be
combined
with
bioactive
ingredients
improve
performance
healing
applications.
Stimulus-responsive
respond
specifically
the
environment
meet
needs
different
stages.
This
review
summarizes
material
types,
structure,
properties,
design
considerations,
formulation
strategies
for
hydrogel
used
healing.
We
discuss
various
types
recently
developed
dressings,
highlights
importance
tailoring
physicochemical
addresses
potential
challenges
preparing
dressings.
