Chemical Society Reviews,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
This
tutorial
review
presents
the
development
of
advanced
immunomodulatory
hydrogels
strategically
designed
to
address
chronic
inflammation
through
their
intrinsic
properties.
Advances in Polymer Technology,
Год журнала:
2024,
Номер
2024(1)
Опубликована: Янв. 1, 2024
Poly(N‐isopropylacrylamide)
(PNIPAM)
is
a
versatile
polymer
known
for
its
phase
transition
properties,
exhibiting
lower
critical
solution
temperature
(LCST)
of
approximately
32°C.
Below
this
temperature,
PNIPAM
hydrophilic,
while
above
it,
the
becomes
hydrophobic,
making
it
ideal
thermosensitive
drug
delivery
systems
(DDSs).
In
tissue
engineering,
provides
biocompatible,
nontoxic
and
stimuli‐responsive
surface
cell
culture.
Its
nature
ensures
safety
in
medical
applications.
enhances
biosensing
diagnostics
through
affinity
biomolecules,
improving
accuracy.
Widely
used
hydrogels,
smart
textiles,
soft
robotics
various
applications,
adapts
to
environmental
changes.
straightforward
synthesis
allows
creation
diverse
copolymers
composites,
applicable
selective
reactions
conjugations
with
fluorescent
tags
or
chemical
modifications.
PNIPAM’s
versatility
extends
pH‐responsive
alternatives,
broadening
application
spectrum.
Practical
examples
include
separation
water
treatment
cleaning
processes.
This
discussion
explores
biomedical
particularly
cancer
treatment,
photothermal
therapy
(PTT)
photodynamic
(PDT),
gene
imaging.
Additionally,
highlights
noncancerous
such
as
small
interfering
RNA
(siRNA)
targeting
oncogenes
detailed
imaging
deep
tumour
tissues.
Advanced Functional Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 3, 2025
Abstract
The
application
of
these
NIPAm‐based
temperature‐sensitive
hydrogels
in
wearable
sensing
is
limited
by
the
inability
to
achieve
a
long‐lasting
temperature
response
and
adaptive
optical
regulation
due
water
loss
hydrogel,
avoid
phenomenon
detachment
external
touch,
mutual
interference
between
stress
signals.
Here,
sandwich‐structured
organogel
sensors
(SOGS)
are
prepared
based
on
solvent
modulation
interfacial
fusion
cross‐linking
strategies
asymmetric‐adhesion,
regulation,
simultaneous
human
motion
without
Modulation
properties
through
hydrogen
bonding
glycol
amide
groups
for
long‐term
(10–30
°C)
infrared
ultraviolet
regulation.
Adhesive
conductive
introduced
under
an
strategy
unilateral
adhesion
(67.28
kPa
pig
skin)
sensing.
intermediate
layer
prevents
In
conclusion,
provides
new
idea
developing
novel
responsive
gels,
facile
method
unilaterally
adherent,
interference‐resistant,
multifunctional
sensors.
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(16), С. 9100 - 9100
Опубликована: Авг. 22, 2024
The
impressive
adhesive
capacity
of
marine
mussels
has
inspired
various
fascinating
designs
in
biomedical
fields.
Mussel-inspired
injectable
hydrogels,
as
a
type
promising
mussel-inspired
material,
have
attracted
much
attention
due
to
their
minimally
invasive
property
and
desirable
functions
provided
by
components.
In
recent
decades,
hydrogels
been
designed
widely
applied
numerous
rational
incorporation
catechol
groups
endows
the
with
potential
exhibit
many
properties,
including
tissue
adhesiveness
self-healing,
antimicrobial,
antioxidant
capabilities,
broadening
applications
this
review,
we
first
give
brief
introduction
adhesion
mechanism
characteristics
hydrogels.
Further,
typical
design
strategies
are
summarized.
methodologies
for
integrating
into
polymers
crosslinking
methods
discussed
section.
addition,
systematically
overview
applications,
focus
on
how
unique
properties
these
benefit
challenges
perspectives
last
This
review
may
provide
new
inspiration
novel
bioinspired
facilitate
application
Chemical Communications,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
This
review
discusses
design
strategies
for
external
stimuli-driven
hydrogels
with
in
situ
catalytic
processes.
It
highlights
precise
control
over
the
properties,
elucidating
regulatory
mechanisms
and
deepening
understanding
of
applications.