Biomedical applications of NIR-II organic small molecule fluorescent probes in different organs
Coordination Chemistry Reviews,
Год журнала:
2024,
Номер
519, С. 216122 - 216122
Опубликована: Авг. 6, 2024
Язык: Английский
Zero-Crosstalk Tumor-Targeting Ratiometric Near-Infrared γ-Glutamyltranspeptidase Probe for Fluorescent-Guided Surgical Resection of Orthotopic Hepatic Tumor
Analytical Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 3, 2025
The
challenge
of
"false
positive"
signals
significantly
complicates
tumor
localization
and
surgical
resection,
which
are
pivotal
for
successful
surgeries.
Therefore,
the
development
a
method
preoperative
intraoperative
margin
determination
holds
considerable
promise
improving
outcomes.
In
this
study,
zero-crosstalk
ratiometric
tumor-targeting
near-infrared
(NIR)
fluorescent
probe
was
developed
precise
cancer
diagnosis
navigation
via
NIR
fluorescence
imaging.
This
integrates
moiety
that
selectively
homes
in
on
hepatocellular
carcinoma
cells
exhibits
highly
sensitive
response
to
γ-glutamyltranspeptidase
(GGT),
characterized
by
substantial
emission
shift
from
830
650
nm.
unique
property
enhances
its
effectiveness
early
imaging-guided
surgery
resection.
Furthermore,
successfully
monitors
GGT
activity
blood,
cells,
vivo,
endowing
potential
clinic.
Due
efficient
targeting
situ
both
subcutaneous
tumors
orthotopic
hepatic
tumors,
accurate
detection
capability
tumors.
Additionally,
leveraging
imaging,
can
serve
as
sprayable
tool
delineating
margins
with
precision,
thereby
furnishing
real-time
imaging
guidance
during
resection
surgery.
Язык: Английский
NIR-II absorbing aza-BODIPY with the D-A-A’ framework for PTT/PDT co-therapy
Chinese Chemical Letters,
Год журнала:
2025,
Номер
unknown, С. 111041 - 111041
Опубликована: Март 1, 2025
Язык: Английский
ATP-Responsive ZIF-based NIR Fluorescent Nanosystem for Enhanced Chemo-Photodynamic Therapy of Tumors
Nanoscale,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
An
ATP-responsive
fluorescence
nanosystem
for
chemo-photodynamic
therapy
is
reported.
The
can
avoid
premature
drug
leakage
and
enhance
local
delivery.
Язык: Английский
A NIR-II Fluorescence Probe for Tracking Oxidative Stress in Plants Induced by Metal Contaminants
Analytical Methods,
Год журнала:
2024,
Номер
16(48), С. 8316 - 8323
Опубликована: Янв. 1, 2024
An
activatable
NIR-II
probe
has
been
developed
for
tracking
metal
ion-induced
oxidative
stress
in
plants,
which
generates
fluorescence
signals
response
to
NO
and
is
good
advancing
plant
health
assessment
environmental
monitoring.
Язык: Английский
Synthesis of Fluorescent Functionalized Polyacrylamide and Detection of Cu2+ and CN– in a Pure Water System
ACS Applied Polymer Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 23, 2024
In
this
paper,
a
fluorescent
functionalized
polyacrylamide
material
(P)
was
prepared
by
free
radical
precipitation
polymerization
based
on
coumarin
derivative
(COMN)
and
acrylamide
(AM).
The
chemical
structure
composition
of
P
were
analyzed
1H
NMR,
UV–vis,
FT-IR
spectra.
results
fluorescence
spectra
common
cations
illustrate
that
can
realize
the
sensitive
detection
copper
(Cu2+)
within
30
s
in
pure
water
system,
quenching
rate
is
as
high
95.47%,
limit
7.2
nM.
It
worth
noting
above
system
rapidly
changed
from
green
to
orange
0.5
s.
addition,
anions
reveal
P/Cu2+
had
strong
interaction
with
cyanide
(CN–)
(0–180
μM),
39.12
cell
imaging
test
show
still
manifests
good
response
Cu2+
CN–
HeLa
cells,
which
provides
new
method
for
these
ions
vivo.
Язык: Английский