Synthesis of Fluorescent Functionalized Polyacrylamide and Detection of Cu2+ and CN– in a Pure Water System DOI
Xiongjie Zhang, Liwei Hou, Yong Zhang

et al.

ACS Applied Polymer Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 23, 2024

In this paper, a fluorescent functionalized polyacrylamide material (P) was prepared by free radical precipitation polymerization based on coumarin derivative (COMN) and acrylamide (AM). The chemical structure composition of P were analyzed 1H NMR, UV–vis, FT-IR spectra. results fluorescence spectra common cations illustrate that can realize the sensitive detection copper (Cu2+) within 30 s in pure water system, quenching rate is as high 95.47%, limit 7.2 nM. It worth noting above system rapidly changed from green to orange 0.5 s. addition, anions reveal P/Cu2+ had strong interaction with cyanide (CN–) (0–180 μM), 39.12 cell imaging test show still manifests good response Cu2+ CN– HeLa cells, which provides new method for these ions vivo.

Language: Английский

Biomedical applications of NIR-II organic small molecule fluorescent probes in different organs DOI
Lizhen Xu, Qian Zhang, Xin Wang

et al.

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 519, P. 216122 - 216122

Published: Aug. 6, 2024

Language: Английский

Citations

17
Zero-Crosstalk Tumor-Targeting Ratiometric Near-Infrared γ-Glutamyltranspeptidase Probe for Fluorescent-Guided Surgical Resection of Orthotopic Hepatic Tumor DOI
Zhichao Yang,

ZhiHao Yang,

Zhiqiang Wang

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 3, 2025

The challenge of "false positive" signals significantly complicates tumor localization and surgical resection, which are pivotal for successful surgeries. Therefore, the development a method preoperative intraoperative margin determination holds considerable promise improving outcomes. In this study, zero-crosstalk ratiometric tumor-targeting near-infrared (NIR) fluorescent probe was developed precise cancer diagnosis navigation via NIR fluorescence imaging. This integrates moiety that selectively homes in on hepatocellular carcinoma cells exhibits highly sensitive response to γ-glutamyltranspeptidase (GGT), characterized by substantial emission shift from 830 650 nm. unique property enhances its effectiveness early imaging-guided surgery resection. Furthermore, successfully monitors GGT activity blood, cells, vivo, endowing potential clinic. Due efficient targeting situ both subcutaneous tumors orthotopic hepatic tumors, accurate detection capability tumors. Additionally, leveraging imaging, can serve as sprayable tool delineating margins with precision, thereby furnishing real-time imaging guidance during resection surgery.

Language: Английский

Citations

0
NIR-II absorbing aza-BODIPY with the D-A-A’ framework for PTT/PDT co-therapy DOI
Xin Zhang,

Ziyue Xi,

Dongxiang Zhang

et al.

Chinese Chemical Letters, Journal Year: 2025, Volume and Issue: unknown, P. 111041 - 111041

Published: March 1, 2025

Language: Английский

Citations

0
ATP-Responsive ZIF-based NIR Fluorescent Nanosystem for Enhanced Chemo-Photodynamic Therapy of Tumors DOI
Sisi Chen,

Xiao-Fan Xu,

Wei-Qun Deng

et al.

Nanoscale, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

An ATP-responsive fluorescence nanosystem for chemo-photodynamic therapy is reported. The can avoid premature drug leakage and enhance local delivery.

Language: Английский

Citations

1
A NIR-II Fluorescence Probe for Tracking Oxidative Stress in Plants Induced by Metal Contaminants DOI

Gaowei Deng,

Lihe Sun, Fang Zeng

et al.

Analytical Methods, Journal Year: 2024, Volume and Issue: 16(48), P. 8316 - 8323

Published: Jan. 1, 2024

An activatable NIR-II probe has been developed for tracking metal ion-induced oxidative stress in plants, which generates fluorescence signals response to NO and is good advancing plant health assessment environmental monitoring.

Language: Английский

Citations

0
Synthesis of Fluorescent Functionalized Polyacrylamide and Detection of Cu2+ and CN– in a Pure Water System DOI
Xiongjie Zhang, Liwei Hou, Yong Zhang

et al.

ACS Applied Polymer Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 23, 2024

In this paper, a fluorescent functionalized polyacrylamide material (P) was prepared by free radical precipitation polymerization based on coumarin derivative (COMN) and acrylamide (AM). The chemical structure composition of P were analyzed 1H NMR, UV–vis, FT-IR spectra. results fluorescence spectra common cations illustrate that can realize the sensitive detection copper (Cu2+) within 30 s in pure water system, quenching rate is as high 95.47%, limit 7.2 nM. It worth noting above system rapidly changed from green to orange 0.5 s. addition, anions reveal P/Cu2+ had strong interaction with cyanide (CN–) (0–180 μM), 39.12 cell imaging test show still manifests good response Cu2+ CN– HeLa cells, which provides new method for these ions vivo.

Language: Английский

Citations

0