Bioengineering,
Год журнала:
2025,
Номер
12(6), С. 579 - 579
Опубликована: Май 28, 2025
Flexoelectricity
arises
in
materials
under
strain
gradients,
which
can
be
particularly
significant
for
situations
the
existence
of
other
electromechanical
properties
is
absent
or
generating
large
flexoelectric
achievable.
This
effect
has
also
been
observed
some
biological
materials,
whose
understanding
hugely
help
to
further
enhance
our
vital
processes
like
mechanotransduction,
as
well
development
applications
regenerative
medicine
and
drug
delivery.
While
field
flexoelectricity
a
relevant
topic
relatively
new
still
developing,
current
study
aims
review
available
results
on
effects
such
cells
cell
membranes,
hearing
mechanisms,
bone,
their
potential
biomedical
research.
Therefore,
we
first
provide
brief
background
two
main
couplings
(piezoelectricity
flexoelectricity)
further,
how
experimentally
theoretically
identified.
We
then
different
aim
study.
Within
that,
additional
emphasis
influence
this
bone
remodeling.
In
particular,
outlines
limitations
provides
directions
future
work,
emphasizing
crucial
role
next-generation
devices
optimizing
function
area
Journal of Molecular Pathology,
Год журнала:
2024,
Номер
5(4), С. 437 - 453
Опубликована: Окт. 5, 2024
The
extracellular
matrix
is
an
organized
three-dimensional
network
of
protein-based
molecules
and
other
macromolecules
that
provide
structural
biochemical
support
to
tissues.
Depending
on
its
properties,
the
influences
cell
adhesion
signal
transduction
and,
in
general,
can
influence
differentiation
proliferation
through
specific
mechanisms
chemical
mechanical
sensing.
development
body
tissues
during
ontogenesis
accompanied
by
changes
not
only
cells
but
also
composition
properties
matrix.
Similarly,
tumor
carcinogenesis
a
continuous
change
cells,
called
‘oncomatrix’,
as
matures,
from
primary
focus
stage
metastasis.
In
this
paper,
characteristics
are
considered,
well
evolution
patterns
be
used
biomarkers
oncological
diseases
potential
targets
for
promising
anti-tumor
therapies.
Materials Research Express,
Год журнала:
2025,
Номер
12(1), С. 015405 - 015405
Опубликована: Янв. 1, 2025
Abstract
Nanofibers
are
considered
promising
materials
for
tissue
engineering
applications
due
to
their
ability
promote
cell
adhesion
and
form
desired
environments
where
new
can
grow.
Furthermore,
we
evaluated
the
impact
of
increasing
concentration
(1–6
wt%)
HAp
on
morphology
subsequent
consequences
regarding
mechanical
properties,
wettability,
biodegradative
nature
wrinkle-free
PVA/collagen
nanofiber
scaffolds
fabricated
by
electrospinning.
FTIR
SEM
were
used
analyze
functional
groups
surface
observe
morphological
characteristics
those
particles.
revealed
that
when
was
enhanced,
a
finer
fiber
with
diameters
in
range
80–500
nm
obtained.
The
test
demonstrated
better
properties
composites
load.
In
addition,
water
contact
angle
decreased
(a
faster
degradation
rate),
which
consistent
higher
suitability
degradation.
Bioengineering,
Год журнала:
2025,
Номер
12(1), С. 52 - 52
Опубликована: Янв. 9, 2025
The
shortage
of
tissues
and
damaged
organs
led
to
the
development
tissue
engineering.
Biological
scaffolds,
created
from
extracellular
matrix
(ECM)
tissues,
have
emerged
as
a
promising
solution
for
transplants.
ECM
decellularized
auricular
cartilage
is
potential
tool
producing
ideal
scaffolds
recellularization
implantation
new
in
areas.
In
order
be
classified
an
scaffold,
it
must
acellular,
preserving
its
proteins
physical
characteristics
necessary
cell
adhesion.
This
study
aimed
develop
decellularization
protocol
pig
ear
evaluate
integrity
ECM.
Four
tests
were
performed
using
different
methods
protocols,
with
four
ears
which
skin
subcutaneous
removed,
leaving
only
cartilage.
most
efficient
was
combination
trypsin
sodium
hydroxide
(0.2
N)
SDS
(1%)
without
altering
conformation
or
collagen
architecture.
conclusion,
observed
that
difficult
decellularize,
influenced
by
material
size,
exposure
time,
composition
solution.
Freezing
thawing
did
not
affect
procedure.
sample
thickness
significantly
impacted
time.
Cell
adhesion
is
a
fundamental
necessity
for
anchorage-dependent
cells
to
thrive
in
the
matrix.
This
process
serves
as
initial
stage
sequence
of
cellular
activities,
which
includes
cell
diffusion,
migration,
proliferation,
and
differentiation.
study
introduces
novel
surface
modification
designed
engineered
enhance
attachment
cholangiocyte
organoids
facilitate
spreading
cholangiocytes
on
polymer
surface.
Our
findings
revealed
that
recruiting
collagen
layer
polydopamine
(PDA)
nanoparticle
coating
poly(lactide-co-trimethylene
carbonate)
(PLATMC)
plays
key
role
attracting
liver
enhancing
migration.
finding
has
promising
results
generating
two-dimensional
(2D)
monolayer
through
organoid
subsequent
integration.
The
innovative
approach
combines
with
culture
technique,
offering
significant
potential
advancing
bile
duct
regenerative
medicine
developing
more
complex
three-dimensional
(3D)
tissues
vitro.
IGI Global eBooks,
Год журнала:
2025,
Номер
unknown, С. 181 - 218
Опубликована: Апрель 25, 2025
Biomaterials
have
been
developed
in
the
medical
field
as
an
innovation
evolved
for
sustainable
therapeutic
and
surgical
approaches.
These
materials
comprise
natural
synthetic
polymers
which
degrades
naturally
to
nontoxic
by-products
within
biological
systems.
They
can
offer
temporary
structural
support
encourage
tissue
regeneration,
makes
them
useful
regenerative
medicine,
drug
delivery
systems,
implants.
This
chapter
includes
biodegradable
engineering
dental
care
materials,
representing
new
options
permanent
Nanocomposites
doped
with
nanoparticles
such
hydroxyapatite
bioactive
glasses
improve
mechanical
strength,
biocompatibility,
bioactivity,
proving
more
prominent
implants,
integration
is
crucial
here.
Continued
study
positioning
dramatically
change
how
effective
achieved,
marrying
clinician's
needs
demands
of
environmental
stewardship.
Frontiers in Chemistry,
Год журнала:
2025,
Номер
13
Опубликована: Апрель 28, 2025
Using
electrospinning
for
nanofiber
production,
we
can
create
unique
materials
with
multiple
applications
in
various
industries,
including
medical
bandages
and
wound
dressings.
One
of
the
most
important
features
these
using
technique,
is
incorporation
compounds
metals
into
their
structure.
In
this
study,
a
new
metal-organic
framework
(MOF)
was
synthesized
from
rhodium,
metal
significant
biological
potential,
which
then
used
to
produce
nanofibers
(Rh-MOF/PVA-PVP
nanofiber)
by
mixing
polyvinyl
alcohol
(PVA)
polyvinylpyrrolidone
(PVP).
The
newly
tested
against
common
microbial
skin
pathogens
cancer
cells,
showing
inhibition.
Specifically,
an
IC50
value
19.45
μg/mL
cells
MIC
values
ranging
4
64
μg
pathogenic
strains
were
observed.
This
notable
inhibitory
ability
be
attributed
both
physical
characteristics
(with
specific
surface
area
2,348
m2/g),
chemical
factors,
active
present
its
rhodium
(Rh)
Rh-MOF/PVA-PVP
has
potential
use
developing
bioactive
bandages,
