Bioengineering,
Journal Year:
2025,
Volume and Issue:
12(1), P. 52 - 52
Published: Jan. 9, 2025
The
shortage
of
tissues
and
damaged
organs
led
to
the
development
tissue
engineering.
Biological
scaffolds,
created
from
extracellular
matrix
(ECM)
tissues,
have
emerged
as
a
promising
solution
for
transplants.
ECM
decellularized
auricular
cartilage
is
potential
tool
producing
ideal
scaffolds
recellularization
implantation
new
in
areas.
In
order
be
classified
an
scaffold,
it
must
acellular,
preserving
its
proteins
physical
characteristics
necessary
cell
adhesion.
This
study
aimed
develop
decellularization
protocol
pig
ear
evaluate
integrity
ECM.
Four
tests
were
performed
using
different
methods
protocols,
with
four
ears
which
skin
subcutaneous
removed,
leaving
only
cartilage.
most
efficient
was
combination
trypsin
sodium
hydroxide
(0.2
N)
SDS
(1%)
without
altering
conformation
or
collagen
architecture.
conclusion,
observed
that
difficult
decellularize,
influenced
by
material
size,
exposure
time,
composition
solution.
Freezing
thawing
did
not
affect
procedure.
sample
thickness
significantly
impacted
time.
Materials Research Express,
Journal Year:
2025,
Volume and Issue:
12(1), P. 015405 - 015405
Published: Jan. 1, 2025
Abstract
Nanofibers
are
considered
promising
materials
for
tissue
engineering
applications
due
to
their
ability
promote
cell
adhesion
and
form
desired
environments
where
new
can
grow.
Furthermore,
we
evaluated
the
impact
of
increasing
concentration
(1–6
wt%)
HAp
on
morphology
subsequent
consequences
regarding
mechanical
properties,
wettability,
biodegradative
nature
wrinkle-free
PVA/collagen
nanofiber
scaffolds
fabricated
by
electrospinning.
FTIR
SEM
were
used
analyze
functional
groups
surface
observe
morphological
characteristics
those
particles.
revealed
that
when
was
enhanced,
a
finer
fiber
with
diameters
in
range
80–500
nm
obtained.
The
test
demonstrated
better
properties
composites
load.
In
addition,
water
contact
angle
decreased
(a
faster
degradation
rate),
which
consistent
higher
suitability
degradation.
Langmuir,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 11, 2025
Cell
adhesion
is
a
fundamental
necessity
for
anchorage-dependent
cells
to
thrive
in
the
matrix.
This
process
serves
as
initial
stage
sequence
of
cellular
activities,
which
includes
cell
diffusion,
migration,
proliferation,
and
differentiation.
study
introduces
novel
surface
modification
designed
engineered
enhance
attachment
cholangiocyte
organoids
facilitate
spreading
cholangiocytes
on
polymer
surface.
Our
findings
revealed
that
recruiting
collagen
layer
polydopamine
(PDA)
nanoparticle
coating
poly(lactide-co-trimethylene
carbonate)
(PLATMC)
plays
key
role
attracting
liver
enhancing
migration.
finding
has
promising
results
generating
two-dimensional
(2D)
monolayer
through
organoid
subsequent
integration.
The
innovative
approach
combines
with
culture
technique,
offering
significant
potential
advancing
bile
duct
regenerative
medicine
developing
more
complex
three-dimensional
(3D)
tissues
vitro.
IGI Global eBooks,
Journal Year:
2025,
Volume and Issue:
unknown, P. 181 - 218
Published: April 25, 2025
Biomaterials
have
been
developed
in
the
medical
field
as
an
innovation
evolved
for
sustainable
therapeutic
and
surgical
approaches.
These
materials
comprise
natural
synthetic
polymers
which
degrades
naturally
to
nontoxic
by-products
within
biological
systems.
They
can
offer
temporary
structural
support
encourage
tissue
regeneration,
makes
them
useful
regenerative
medicine,
drug
delivery
systems,
implants.
This
chapter
includes
biodegradable
engineering
dental
care
materials,
representing
new
options
permanent
Nanocomposites
doped
with
nanoparticles
such
hydroxyapatite
bioactive
glasses
improve
mechanical
strength,
biocompatibility,
bioactivity,
proving
more
prominent
implants,
integration
is
crucial
here.
Continued
study
positioning
dramatically
change
how
effective
achieved,
marrying
clinician's
needs
demands
of
environmental
stewardship.
Frontiers in Chemistry,
Journal Year:
2025,
Volume and Issue:
13
Published: April 28, 2025
Using
electrospinning
for
nanofiber
production,
we
can
create
unique
materials
with
multiple
applications
in
various
industries,
including
medical
bandages
and
wound
dressings.
One
of
the
most
important
features
these
using
technique,
is
incorporation
compounds
metals
into
their
structure.
In
this
study,
a
new
metal-organic
framework
(MOF)
was
synthesized
from
rhodium,
metal
significant
biological
potential,
which
then
used
to
produce
nanofibers
(Rh-MOF/PVA-PVP
nanofiber)
by
mixing
polyvinyl
alcohol
(PVA)
polyvinylpyrrolidone
(PVP).
The
newly
tested
against
common
microbial
skin
pathogens
cancer
cells,
showing
inhibition.
Specifically,
an
IC50
value
19.45
μg/mL
cells
MIC
values
ranging
4
64
μg
pathogenic
strains
were
observed.
This
notable
inhibitory
ability
be
attributed
both
physical
characteristics
(with
specific
surface
area
2,348
m2/g),
chemical
factors,
active
present
its
rhodium
(Rh)
Rh-MOF/PVA-PVP
has
potential
use
developing
bioactive
bandages,
International Journal of Molecular Sciences,
Journal Year:
2025,
Volume and Issue:
26(9), P. 4242 - 4242
Published: April 29, 2025
Bone
defects
caused
by
various
traumas
and
diseases
such
as
osteoporosis,
which
affects
bone
density,
osteosarcoma,
the
integrity
of
structure,
are
now
well
known.
Given
this
situation,
several
innovative
research
projects
have
been
reported
to
improve
orthopedic
methods
technologies
that
positively
contribute
regeneration
affected
tissue,
representing
a
significant
advance
in
regenerative
medicine.
This
review
article
comprehensively
analyzes
transition
from
existing
for
implants
tissue
biomaterials.
These
biomaterials
great
interest
last
decade
due
their
physicochemical
characteristics,
allow
them
overcome
most
common
limitations
traditional
grafting
methods,
availability
risk
rejection
after
application
could
be
achieved
through
an
exhaustive
study
applications
properties
materials
with
potential
medicine,
using
magnetic
nanoparticles
hydrogels
sensitive
external
stimuli,
including
pH
temperature.
In
regard,
describes
relevant
compounds
used
regeneration,
promoting
integration
these
area's
thereby
allowing
preventing
amputation.
Additionally,
types
interactions
between
mesenchymal
stem
cells
effects
on
discussed,
is
critical
developing
optimal
properties.
Furthermore,
mechanisms
action
enhance
osteoconduction
osteoinduction,
ensuring
success
therapies,
analyzed.
enables
treatment
tailored
each
patient's
condition,
avoiding
limb
Consequently,
promising
future
medicine
emerging,
therapies
revolutionize
management
defects,
offering
more
efficient
safer
solutions.
