RESPONSIVE TO ADAPTIVE SUPRAMOLECULAR HYDROGELS FOR DIABETIC WOUND TREATMENT. DOI Creative Commons

Shalini Balakrishnan,

Revathy Remesh,

Kalathil K. Kartha

и другие.

Supramolecular Materials, Год журнала: 2024, Номер unknown, С. 100081 - 100081

Опубликована: Ноя. 1, 2024

Язык: Английский

Chlorogenic acid-assisted dopamine‑sodium alginate composite nanofiber membranes for promoting wound healing DOI
Meng Zhang, Yang Wang,

Xueling Yin

и другие.

Carbohydrate Polymers, Год журнала: 2025, Номер 354, С. 123298 - 123298

Опубликована: Янв. 23, 2025

Язык: Английский

Процитировано

0
Dual ROS/Glucose-Responsive Quercetin-Loaded Supramolecular Hydrogel for Diabetic Wound Healing DOI
Chenguang Liu,

Ronger Ai,

Bizhi Liu

и другие.

Biomacromolecules, Год журнала: 2025, Номер unknown

Опубликована: Фев. 5, 2025

Diabetic wound healing remains a significant challenge due to complex pathological mechanisms, including prolonged inflammation, excessive reactive oxygen species (ROS) accumulation, angiogenesis dysfunction, and increased susceptibility bacterial infection. In this study, we developed dual ROS/glucose-responsive quercetin-loaded supramolecular hydrogel (GPQ hydrogel) for treating diabetic wounds. The was fabricated by incorporating quercetin (QUE) into guanosine–phenylboronic acid (GP) network through dynamic borate ester bonds. Structural characterization revealed the formation of typical G-quadruplex structure in GPQ hydrogel. responsiveness ROS glucose enabled controlled release QUE, effectively addressing abnormal microenvironment diabetes. vitro studies demonstrated excellent antibacterial, antioxidant, anti-inflammatory, pro-angiogenic properties Furthermore, vivo study using full-thickness model streptozotocin-induced rats showed that significantly accelerated closure, enhanced re-epithelialization collagen deposition, promoted compared control GP groups. Immunofluorescence analysis confirmed superior antioxidant effects microenvironment. This presents promising multifunctional biomaterial managing

Язык: Английский

Процитировано

0
Injectable polypeptide/chitosan hydrogel with loaded stem cells and rapid gelation promoting angiogenesis for diabetic wound healing DOI Creative Commons
Cencan Xing,

Liangxuan Hou,

Chunbin Sun

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 306, С. 141578 - 141578

Опубликована: Фев. 27, 2025

Язык: Английский

Процитировано

0
A multiple-crosslinked injectable hydrogel for modulating tissue microenvironment and accelerating infected diabetic wound repair DOI Creative Commons
Zhengduo Zhang,

Yuanyuan Ding,

Huipu Yuan

и другие.

Journal of Nanobiotechnology, Год журнала: 2025, Номер 23(1)

Опубликована: Март 18, 2025

Язык: Английский

Процитировано

0
RESPONSIVE TO ADAPTIVE SUPRAMOLECULAR HYDROGELS FOR DIABETIC WOUND TREATMENT. DOI Creative Commons

Shalini Balakrishnan,

Revathy Remesh,

Kalathil K. Kartha

и другие.

Supramolecular Materials, Год журнала: 2024, Номер unknown, С. 100081 - 100081

Опубликована: Ноя. 1, 2024

Язык: Английский

Процитировано

3