Greenificated Molecularly Imprinted Materials for Advanced Applications

Advanced Materials, Год журнала: 2022, Номер 34(42)

Опубликована: Июнь 23, 2022

Abstract Molecular imprinting technology (MIT) produces artificial binding sites with precise complementarity to substrates and thereby is capable of exquisite molecular recognition. Over five decades evolution, it predicted that the resulting host imprinted materials will overtake natural receptors for research application purposes, but in practice, this has not yet been realized due unsustainability their life cycles (i.e., precursors, creation, use, recycling, end‐of‐life). To address issue, greenificated molecularly polymers (GMIPs) are a new class plastic antibodies have approached sustainability by following one or more greenification principles, while also demonstrating far‐reaching applications compared counterparts. In review, most recent developments delicate design advanced GMIPs six fast‐growing emerging fields surveyed, namely biomedicine/therapy, catalysis, energy harvesting/storage, nanoparticle detection, gas sensing/adsorption, environmental remediation. addition, distinct features highlighted, optimal means utilize these attaining incredibly discussed. Importantly, obscure technical challenges MIT revealed, conceivable solutions offered. Lastly, several perspectives on future directions proposed.

Язык: Английский

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Chiral molecular imprinting-based SERS detection strategy for absolute enantiomeric discrimination

Nature Communications, Год журнала: 2022, Номер 13(1)

Опубликована: Сен. 30, 2022

Abstract Chiral discrimination is critical in environmental and life sciences. However, an ideal chiral strategy has not yet been developed because of the inevitable nonspecific binding entity wrong enantiomers or insufficient intrinsic optical activities molecules. Here, we propose “inspector” recognition mechanism (IRM), which implemented on a imprinted polydopamine (PDA) layer coated surface-enhanced Raman scattering (SERS) tag layer. The IRM works based permeability change PDA after scrutiny by inspector molecule. Good enantiomer can specifically recognize fully fill cavities, whereas cannot. Then linear shape aminothiol molecule, as status introduced, only percolate through vacant nonspecifically occupied inducing SERS signal to decrease. Accordingly, chirality information exclusively stems from good specific binding, while curbed. benefits sensitivity versatility, enabling absolute wide variety molecules regardless size, functional groups, polarities, activities, scattering, number centers.

Язык: Английский

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A brief overview of molecularly imprinted polymers: Highlighting computational design, nano and photo-responsive imprinting

Talanta Open, Год журнала: 2021, Номер 4, С. 100072 - 100072

Опубликована: Окт. 19, 2021

The present review provide a brief overview of the basic aspects molecular imprinting technology covering template molecules, functional monomers, crosslinking agents, initiators, characterization methods and application by emphasizing on novel polymer materials. Compare to other reviews, various computational designing imprinted polymers, carbon based nano-imprinting stimuli-responsive polymers are highlighted here in review. This comprises critical account most recent developments field imprinting. It is directed towards broad spectrum readers like separation science, material, synthetic, analytical bioorganic chemists who make use photoresponsive materials for specific purpose.

Язык: Английский

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Development of dispersive solid-liquid extraction method based on organic polymers followed by deep eutectic solvents elution; application in extraction of some pesticides from milk samples prior to their determination by HPLC-MS/MS

Analytica Chimica Acta, Год журнала: 2022, Номер 1199, С. 339570 - 339570

Опубликована: Фев. 2, 2022

Язык: Английский

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Technical Challenges of Molecular-Imprinting-Based Optical Sensors for Environmental Pollutants

Langmuir, Год журнала: 2022, Номер 38(19), С. 5963 - 5967

Опубликована: Май 5, 2022

Combating environmental pollution constantly requires new affinity tools to selectively recognize and sensitively detect them. Molecularly imprinted polymers (MIPs) are plastic antibodies that have exhibited great potential as recognition units in optical sensing platforms monitor wide varieties of pollutants, including ionic species, organic compounds, gases, even manufactured nanoparticles. The construction, strategies, applications molecular-imprinting-based sensors (MI-OSs) been discussed recent reviews, thus we deliberately set them aside. This Perspective elaborates on unanswered questions main approaches being taken address the challenges MI-OS technologies, which less considered until now. Specifically, highlight obscure technical aspects fabrication validation impact their practical importantly offer conceivable solutions related problems bridge research gap.

Язык: Английский

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Recent advances in the application of molecularly imprinted polymers (MIPs) in food analysis

Food Control, Год журнала: 2022, Номер 139, С. 109074 - 109074

Опубликована: Май 4, 2022

Язык: Английский

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Tips and tricks for successful preparation of molecularly imprinted polymers for analytical applications: A critical review

Microchemical Journal, Год журнала: 2023, Номер 193, С. 109152 - 109152

Опубликована: Июль 31, 2023

Язык: Английский

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Multi-templates molecularly imprinted polymers for simultaneous recognition of multiple targets: From academy to application

TrAC Trends in Analytical Chemistry, Год журнала: 2023, Номер 166, С. 117173 - 117173

Опубликована: Июль 14, 2023

Язык: Английский

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Molecularly imprinted polymers (MIPs): emerging biomaterials for cancer theragnostic applications

Biomaterials Research, Год журнала: 2023, Номер 27(1)

Опубликована: Фев. 9, 2023

Cancer is a disease caused by abnormal cell growth that spreads through other parts of the body and threatens life destroying healthy tissues. Therefore, numerous techniques have been employed not only to diagnose monitor progress cancer in precise manner but also develop appropriate therapeutic agents with enhanced efficacy safety profiles. In this regard, molecularly imprinted polymers (MIPs), synthetic receptors recognize targeted molecules high affinity selectivity, intensively investigated as one most attractive biomaterials for theragnostic approaches. This review describes diverse synthesis strategies provide rationale behind these antibodies provides selective overview recent vitro vivo targeting biomarkers diagnosis applications. Taken together, topics discussed concise guidelines development novel MIP-based systems more precisely promote successful treatment. Molecularly The aim

Язык: Английский

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Molecular Imprinting Technology Enables Proactive Capture of Nitrogen for Boosted Ammonia Synthesis under Ambient Conditions

Advanced Materials, Год журнала: 2023, Номер 35(51)

Опубликована: Авг. 9, 2023

Electrochemical nitrogen reduction reaction (NRR) is a burgeoning field for green and sustainable ammonia production, in which numerous potential catalysts emerge endlessly. However, satisfactory performances are still not realized under practical applications due to the limited solubility sluggish diffusion of at interface. Herein, molecular imprinting technology adopted construct an adlayer with abundant imprints on electrocatalyst, capable selectively recognizing proactively aggregating high-concentrated interface while hindering access overwhelming water simultaneously. With this favorable microenvironment, can preferentially occupy active surface, NRR equilibrium be positively shifted facilitate kinetics. Approximately threefold improvements both production rate (185.7 µg h-1 mg-1 ) Faradaic efficiency (72.9%) achieved by metal-free catalyst compared bare one. It believed that strategy should general method find further applicability or even other reactions facing similar challenges.

Язык: Английский

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