Journal of Hazardous Materials,
Год журнала:
2023,
Номер
458, С. 131873 - 131873
Опубликована: Июнь 16, 2023
Per-
and
polyfluoroalkyl
substances
(PFAS)
have
gained
significant
attention
as
emerging
contaminants
due
to
their
persistence,
abundance,
adverse
health
effects.
Consequently,
the
urgent
need
for
ubiquitous
effective
sensors
capable
of
detecting
quantifying
PFAS
in
complex
environmental
samples
has
become
a
priority.
In
this
study,
we
present
development
an
ultrasensitive
molecularly
imprinted
polymer
(MIP)
electrochemical
sensor
tailored
by
chemically
vapour-deposited
boron
nitrogen
codoped
diamond-rich
carbon
nanoarchitectures
selective
determination
perfluorooctanesulfonic
acid
(PFOS).
This
approach
allows
multiscale
reduction
MIP
heterogeneities,
leading
improved
selectivity
sensitivity
PFOS
detection.
Interestingly,
peculiar
nanostructures
induce
specific
distribution
binding
sites
MIPs
that
exhibit
strong
affinity
PFOS.
The
designed
demonstrated
low
limit
detection
(1.2
μg
L-1)
exhibited
satisfactory
stability.
To
gain
further
insights
into
molecular
interactions
between
surfaces,
electropolymerised
MIP,
analyte,
set
density
functional
theory
(DFT)
calculations
was
performed.
Validation
sensor's
performance
carried
out
successfully
determining
concentrations
real
samples,
such
tap
water
treated
wastewater,
with
average
recovery
rates
consistent
UHPLC-MS/MS
results.
These
findings
demonstrate
potential
MIP-supported
pollution
monitoring,
specifically
targeting
contaminants.
proposed
design
holds
promise
situ
monitoring
devices
operating
under
relevant
conditions.
Biomaterials Research,
Год журнала:
2023,
Номер
27(1)
Опубликована: Фев. 9, 2023
Cancer
is
a
disease
caused
by
abnormal
cell
growth
that
spreads
through
other
parts
of
the
body
and
threatens
life
destroying
healthy
tissues.
Therefore,
numerous
techniques
have
been
employed
not
only
to
diagnose
monitor
progress
cancer
in
precise
manner
but
also
develop
appropriate
therapeutic
agents
with
enhanced
efficacy
safety
profiles.
In
this
regard,
molecularly
imprinted
polymers
(MIPs),
synthetic
receptors
recognize
targeted
molecules
high
affinity
selectivity,
intensively
investigated
as
one
most
attractive
biomaterials
for
theragnostic
approaches.
This
review
describes
diverse
synthesis
strategies
provide
rationale
behind
these
antibodies
provides
selective
overview
recent
vitro
vivo
targeting
biomarkers
diagnosis
applications.
Taken
together,
topics
discussed
concise
guidelines
development
novel
MIP-based
systems
more
precisely
promote
successful
treatment.
Molecularly
The
aim
Molecules,
Год журнала:
2023,
Номер
28(1), С. 335 - 335
Опубликована: Янв. 1, 2023
The
abuse
and
residues
of
antibiotics
have
a
great
impact
on
the
environment
organisms,
their
determination
has
become
very
important.
Due
to
low
contents,
varieties
complex
matrices,
effective
recognition,
separation
enrichment
are
usually
required
prior
determination.
Molecularly
imprinted
polymers
(MIPs),
kind
highly
selective
polymer
prepared
via
molecular
imprinting
technology
(MIT),
used
widely
in
analytical
detection
antibiotics,
as
adsorbents
solid-phase
extraction
(SPE)
recognition
elements
sensors.
Herein,
recent
advances
MIPs
for
antibiotic
residue
analysis
reviewed.
Firstly,
several
new
preparation
techniques
detecting
briefly
introduced,
including
surface
imprinting,
nanoimprinting,
living/controlled
radical
polymerization,
multi-template
multi-functional
monomer
dummy
template
imprinting.
Secondly,
SPE
modes
based
summarized,
namely
packed
SPE,
magnetic
dispersive
matrix
extraction,
microextraction,
stir-bar
sorptive
pipette-tip
SPE.
Thirdly,
basic
principles
MIP-based
sensors
three
sensing
modes,
electrochemical
sensing,
optical
mass
also
outlined.
Fourthly,
research
progress
molecularly
SPEs
(MISPEs)
electrochemical/optical/mass
various
environmental
food
samples
since
2018
comprehensively
reviewed,
sulfonamides,
quinolones,
β-lactams
so
on.
Finally,
application
prospects
Analytical Chemistry,
Год журнала:
2024,
Номер
96(16), С. 6417 - 6425
Опубликована: Апрель 12, 2024
Molecular
imprinting-based
surface-enhanced
Raman
scattering
(MI-SERS)
sensors
have
shown
remarkable
potential
from
an
academic
standpoint.
However,
their
practical
applications,
especially
in
the
detection
of
large-size
protein
(≥10
nm),
face
challenges
due
to
lack
versatile
sensing
strategies
and
nonspecific
fouling
matrix
species.
Herein,
we
propose
a
reporter
inspector
mechanism
(RRIM)
implemented
on
protein-imprinted
polydopamine
(PDA)
layer
coated
SERS
active
substrate.
In
RRIM,
after
recognition,
permeability
PDA
imprinted
cavities
undergoes
changes
that
are
scrutinized
by
molecules.
Target
proteins
can
specifically
bind
fully
occupy
cavities,
whereas
species
cannot.
Then,
molecules
with
suitable
size
introduced
serve
as
both
inspectors
recognition
status
inducers
signal,
which
only
penetrate
through
vacant
nonspecifically
filled
cavities.
Consequently,
signal
exclusively
originate
specific
binding
target
proteins,
while
is
curbed.
The
RRIM
enables
reproducible
quantitation
cyanobacteria-specific
model
phycocyanin,
at
level
down
2.6
×
10
