Acta Biomaterialia, Год журнала: 2024, Номер unknown
Опубликована: Сен. 1, 2024
Язык: Английский
Advanced Functional Materials, Год журнала: 2024, Номер 34(44)
Опубликована: Июнь 19, 2024
Abstract Piezocatalysis and piezo‐photocatalysis technology is a continuously developing catalytic based on the piezoelectric effect of catalysts, which breaks barrier between mechanical chemical energy. The polarization field formed by deformation materials proven to effectively manipulate band structures, improve separation electron‐hole pairs enhance activity, thus alleviating energy crises environmental issues. Herein, this review first introduces piezocatalysis piezo‐photocatalysis, comprehensively summarizes synthesis methods piezo(photo)catalysis materials, analyzes discusses measures optimize performance piezo(photo)catalysts. following systematically characteristics development current main piezo(photo)catalytic systems, application principles calculations in combination with practical researches. Subsequently, progress remediation, conversion, biomedical therapy fields presented. In end, challenges, direction, future prospects are prospected.
Язык: Английский
Процитировано
20
Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 159771 - 159771
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
2
Nano Energy, Год журнала: 2024, Номер unknown, С. 110518 - 110518
Опубликована: Ноя. 1, 2024
Язык: Английский
Процитировано
12
Small, Год журнала: 2024, Номер 20(44)
Опубликована: Июль 6, 2024
Abstract Sonodynamic therapy (SDT), featuring noninvasive, deeper penetration, low cost, and repeatability, is a promising approach for deep‐seated tumors. However, the general or only utilization of SDT shows efficiency unsatisfactory treatment outcomes due to complicated tumor microenvironment (TME) process. To circumvent issues, three feasible approaches enhancing SDT‐based therapeutic effects, including sonosensitizer optimization, strategies conquering hypoxia TME, combinational are summarized, with particular focus on combination other modalities, chemodynamic therapy, photodynamic photothermal chemotherapy, starvation gas immunotherapy. In end, current challenges in tumors discussed enhanced effects provided. It envisioned that this review will provide new insight into strategic design high‐efficiency sonosensitizer‐derived nanotheranostics, thereby augmenting accelerating potential clinical transformation.
Язык: Английский
Процитировано
11
Advanced Materials, Год журнала: 2025, Номер unknown
Опубликована: Фев. 13, 2025
Abstract Halide perovskites (HPs), emerging as a noteworthy class of semiconductors, hold great promise for an array optoelectronic applications, including anti‐counterfeiting, light‐emitting diodes (LEDs), solar cells (SCs), and photodetectors, primarily due to their large absorption cross section, high fluorescence efficiency, tunable emission spectrum within the visible region, tolerance lattice defects, well adaptability solution‐based fabrication processes. Unlike luminescent HPs with band‐edge emission, trivalent rare‐earth (RE) ions typically emit low‐energy light through intra‐4f optical transitions, characterized by narrow spectra long lifetimes. When fused, cooperative interactions between REs endow resulting binary composites not only properties inherited from parent materials but also introduce new attributes unattainable either component alone. This review begins fundamental characteristics REs, followed particular focus on impact electronic structures associated energy transfer The advanced synthesis methods utilized prepare HPs, RE‐doped compounds, are overviewed. Furthermore, potential applications summarized across diverse domains, high‐fidelity anticounterfeiting, bioimaging, LEDs, photovoltaics, photodetection, photocatalysis, conclude remaining challenges future research prospects.
Язык: Английский
Процитировано
1
ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown
Опубликована: Март 24, 2025
Breast cancer remains the leading cause of cancer-related deaths among women worldwide, necessitating more effective treatment strategies. Chemotherapy combined with immunotherapy is first-line for breast cancer, but it still suffers from limited therapeutic efficiency and serious side effects, which are usually due to poor delivery efficiency, drug resistance tumor cells, immunosuppressive microenvironment. This study explores development ultrasound-responsive nanobubbles (Ce6/PTX Nbs) targeted imaging sonoimmunotherapy in treatment. By integrating sonodynamic therapy (SDT), chemotherapy, immunotherapy, aim address challenges such as delivery, systemic toxicity, immune suppression conventional therapies. The nanobubbles, composed sonosensitizer chlorin e6 (Ce6)-modified phospholipid loaded chemotherapeutic agent paclitaxel (PTX) enhancing drug-loading capacity, designed precisely target sites via cyclic-RGD peptides. Upon ultrasound activation, Ce6 induces reactive oxygen species (ROS), promoting immunogenic cell death (ICD), while PTX disrupts mitosis, response. nanobubbles' responsiveness facilitates real-time controlled release, maximizing efficacy minimizing effects. Key findings demonstrate that Ce6/PTX Nbs significantly reduced growth a 4T1 model, enhanced activation cGAS-STING pathway, increased infiltration CD8+ T cells both primary distant tumors. In combination anti-PD-L1 checkpoint inhibitors, achieved substantial metastasis. innovative approach offers highly targeted, effective, minimally toxic potential clinical translation its dual capabilities.
Язык: Английский
Процитировано
1
ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 16(9), С. 11194 - 11205
Опубликована: Фев. 23, 2024
Osteomyelitis is primarily caused by bacterial infections, and treatment requires precise sequential therapy, including antibacterial therapy in the early stages bone defect reconstruction later stages. We aimed to synthesize core–shell-structured zinc oxide/silver sulfide heterogeneous nanoparticles (ZnO/Ag2S NPs) using wet chemical methods. Using density functional theory ultraviolet photoelectron spectroscopy, we showed that optimized band structure endowed ZnO/Ag2S NPs with photodynamic properties under near-infrared (NIR) irradiation. Moreover, exhibited a distinguished stable photothermal performance within same wavelength range. With single-wavelength irradiation, achieved bifunctional effect during acute stage of osteomyelitis. Antibacterial action was confirmed through colony-forming unit (CFU) counting assays, scanning electronic microscopy (SEM) observations, live–dead staining, growth curves, quantitative real-time polymerase chain reaction (qPCR) assays. The Ag2S coating on realized sustained release ions, thereby controlling ion concentration. Alkaline phosphatase (ALP) alizarin red S (ARS) qPCR assays good osteogenic effects vitro. These were verified an vivo mouse femur model chronic micro-computed tomography (micro-CT) histological analysis. This study provides novel biocompatible core–shell nanomaterial for two-phase osteomyelitis, contributing versatile nanotherapies infections inflammation.
Язык: Английский
Процитировано
7
Advanced Functional Materials, Год журнала: 2024, Номер unknown
Опубликована: Июль 2, 2024
Abstract The treatment outcomes of nanomedicines against colorectal cancer are severely restricted by their insufficient accumulation in the tumor tissues, unsatisfactory antitumor effect, and weak immunometabolic modulation. To address these issues, flying‐saucer‐shaped nanoheterojunctions coating copper oxide (Cu x O) onto surface PEGylated zinc (ZnO) nanoparticles constructed. When exposed to ultrasound, resultant Cu O@ZnO exhibit increased locomotor activities, facilitating mucus infiltration, deep penetration, cell internalization. decoration O suppresses rapid recombination electrons holes promoting production singlet oxygen hydroxyl radical, which generated through a Fenton‐like chemodynamic reaction sonodynamic reaction. After rectal administration, sono‐chemodynamic plus PD‐L1 antibodies effectively inhibit growth orthotopic distant tumors. It elicits responses inducing immunogenic death, activating interferon genes signaling pathway stimulator, inhibiting glucose transport glycolytic pathways. This combined modality also increases proportion beneficial microbes ( e.g ., Bifidobacterium ) decreases abundance harmful microorganisms Romboutsia intestine. ultrasound antibodies) is promising strategy for synergistic cancer.
Язык: Английский
Процитировано
6
Advanced Energy Materials, Год журнала: 2024, Номер 14(39)
Опубликована: Июль 11, 2024
Abstract Hydrogen (H 2 ) is mainly produced using steam methane reforming, electrolysis, and gasification, which require external energy special catalysts. A new catalyst by combining MoS nanoflowers (NFs) with metal carbide/nitride nanosheets (Mo CTx MXene) to create a nanosheet bending moment. The @Mo CT x heterostructures achieve production rate of 1164.8 µmol g −1 h under an application mechanical force, 4.01 3.06 times higher than Mo alone, due enhanced charge transfer from 's piezoelectricity conductivity. This study introduces pioneering methodology that harnesses gravitational as continuous simulated peristaltic pump, drive the piezocatalytic hydrogen evolution reaction (HER), achieving notable 454.1 over 24 hours demonstrating sustained capability for generation. theoretical calculation results validate piezoelectric potential in water‐flow‐pressure triggered HER systems. system, assuming powered Hoover Dam, will produce 290.9 kmoles per ton daily, equivalent utilizing 19 150 kWh electrocatalytic system. gravity‐driven water flow piezocatalysts H generation demonstrates superior efficiency eliminating common thermal conversion losses, marking significant breakthrough sustainable technologies.
Язык: Английский
Процитировано
6
Nano Energy, Год журнала: 2024, Номер unknown, С. 110415 - 110415
Опубликована: Окт. 1, 2024
Язык: Английский
Процитировано
5