Advanced Functional Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Июнь 1, 2025
Abstract
Tuning
the
functional
properties
of
nanocarriers
has
gained
increasing
interest
in
recent
years
as
a
key
strategy
to
accelerate
clinical
translation
nanomedicine.
Once
come
into
contact
with
biological
fluid
such
blood,
interactions
occur
at
nanocarrier/biological
interface
that
alter
identity
nanocarriers.
As
knowledge
this
field
is
rapidly
evolving,
review
highlights
some
latest
developments
(2021
early
2025)
and
covers
significant
findings
nano‐biointerface.
Specifically,
current
obstacles
achieving
goal
targeting
are
addressed
emphasis
on
formation
impact
adsorbed
proteins,
so‐called
protein
corona.
The
strategies
overcome
these
explored
by
rational
design
using
biomimetic
coatings
(proteins
membranes)
enhance
favorable
between
systems.
challenges
problems
related
gold
standard
(poly(ethylene
glycol)ylation),
availability
for
proteins
(functionalization,
structural
integrity),
etc.,
alternatives
discussed.
Finally,
future
perspectives
discussed
facilitate
International Journal of Medical Sciences,
Год журнала:
2025,
Номер
22(3), С. 528 - 550
Опубликована: Янв. 1, 2025
Background:
Worldwide,
approximately
1.7
billion
people
are
afflicted
with
musculoskeletal
(MSK)
diseases,
posing
significant
health
challenges.
The
introduction
of
single-cell
RNA
sequencing
(scRNA-seq)
technology
provides
novel
insights
and
approaches
to
comprehend
the
onset,
progression,
treatment
MSK
diseases.
Nevertheless,
there
is
a
remarkable
lack
analytical
descriptive
studies
regarding
trajectory,
essential
research
directions,
current
situation,
pivotal
focuses,
upcoming
perspectives.
Therefore,
aim
this
present
comprehensive
overview
advancements
made
in
scRNA-seq
for
disorders
over
past
15
years.
Methods:
It
utilizes
robust
dataset
derived
from
Web
Science
Core
Collection,
encompassing
January
1,
2009,
through
September
6,
2024.
To
achieve
this,
advanced
methodologies
were
applied
conduct
thorough
scientometric
visual
analyses.
Results:
findings
underscore
preeminent
role
China,
which
contributes
63.49%
total
publications,
thereby
exerting
substantial
impact
within
domain.
Notable
contributions
came
institutions
such
as
Shanghai
Jiao
Tong
University,
Sun
Yat-sen
Harvard
Medical
School,
Liu
Yun
being
leading
contributor.
Frontiers
Immunology
published
greatest
number
papers
field.
This
study
identified
joint
bone
neoplasms,
fractures,
intervertebral
disc
degeneration
main
focuses.
Conclusion:
extensive
analysis
benefits
both
experienced
novice
researchers
by
facilitating
immediate
access
critical
data,
fostering
innovation
Humanities and Social Sciences Communications,
Год журнала:
2024,
Номер
11(1)
Опубликована: Авг. 31, 2024
The
rapid
expansion
of
information
technology
and
the
intensification
population
aging
are
two
prominent
features
contemporary
societal
development.
Investigating
older
adults'
acceptance
use
is
key
to
facilitating
their
integration
into
an
information-driven
society.
Given
this
context,
adults
has
emerged
as
a
prioritized
research
topic,
attracting
widespread
attention
in
academic
community.
However,
existing
remains
fragmented
lacks
systematic
framework.
To
address
gap,
we
employed
bibliometric
methods,
utilizing
Web
Science
Core
Collection
conduct
comprehensive
review
literature
on
from
2013
2023.
Utilizing
VOSviewer
CiteSpace
for
data
assessment
visualization,
created
knowledge
mappings
acceptance.
Our
study
multidimensional
methods
such
co-occurrence
analysis,
clustering,
burst
analysis
to:
(1)
reveal
dynamics,
journals,
domains
field;
(2)
identify
leading
countries,
collaborative
networks,
core
institutions
authors;
(3)
recognize
foundational
system
centered
theoretical
model
deepening,
emerging
applications,
evaluation,
uncovering
seminal
observing
shift
early
influential
factor
analyses
empirical
studies
focusing
individual
factors
technologies;
(4)
moreover,
current
hotspots
primarily
areas
influencing
adoption,
human-robot
interaction
experiences,
mobile
health
management,
aging-in-place
technology,
highlighting
evolutionary
context
quality
distribution
themes.
Finally,
recommend
that
future
should
deeply
explore
improvements
models,
long-term
usage,
user
experience
evaluation.
Overall,
presents
clear
framework
field
acceptance,
providing
important
reference
exploration
innovative
applications.
Heliyon,
Год журнала:
2024,
Номер
10(8), С. e29477 - e29477
Опубликована: Апрель 1, 2024
With
the
advances
in
society
and
response
to
changing
times,
college
students
have
had
face
multiple
challenges.
These
challenges
frequently
affect
mental
health
of
students,
leading
significant
consequences
for
their
social
lives,
personal
well-being,
academic
achievements,
thereby
attracting
extensive
societal
attention.
Therefore,
examining
current
status
research
topics
related
can
assist
academia
dissecting
influencing
factors
seeking
solutions
at
source
or
through
early
intervention.
This
contribute
a
better
understanding
effectively
address
this
challenge.
Frontiers in Pharmacology,
Год журнала:
2024,
Номер
15
Опубликована: Май 17, 2024
Background
Cardiovascular
disease
(CVD)
poses
a
significant
global
health
and
economic
challenge,
with
atherosclerosis
being
primary
cause.
Over
the
past
40
years,
substantial
research
has
been
conducted
into
prevention
reversal
of
atherosclerosis,
resulting
in
development
lipid-lowering
agents
such
as
statins
fibrates.
Despite
extensive
literature
formulation
numerous
therapeutic
guidelines
this
domain,
comprehensive
bibliometric
analysis
current
landscape
trends
not
performed.
This
study
aimed
to
elucidate
evolution
milestones
treatments
for
coronary
heart
(CHD)
conjunction
hyperlipidemia
through
analysis,
offering
insights
future
directions
treatment
strategies.
Methods
examined
publications
from
1986
2023
retrieved
Web
Science
database
(Core
Collection).
Utilizing
tools
VOSviewer,
Pajek,
CiteSpace,
we
analyzed
publication
citation
numbers,
H-indexes,
contributions
by
countries
institutions,
authorship,
journal
sources,
keyword
usage
uncover
trajectories
areas
focus.
Results
Our
587
revealed
recent
surge
output,
particularly
post-2003.
The
American
Journal
Cardiology
published
highest
number
studies,
articles,
whereas
Circulation
received
citations
(6,266).
Key
contributors
included
United
States,
Japan,
China,
States
leading
numbers
H-index.
Harvard
University
Leiden
emerged
pivotal
Professors
J.
Wouter
Jukema
Robert
P.
Giugliano
were
identified
experts.
Keyword
disclosed
five
thematic
clusters,
indicating
shift
towards
new
drug
combinations
strategies,
signaling
directions.
Conclusion
last
4
decades
have
seen
notable
rise
on
therapies
CHD
hyperlipidemia,
retaining
world-leading
status.
increase
international
collaboration
aids
innovative
approaches.
PCSK9
inhibitors
combination
therapies,
including
antisense
oligonucleotides
angiopoietin-like
protein
3
inhibitors,
provide
avenues
research,
intending
maximize
safety
efficacy
Frontiers in Pharmacology,
Год журнала:
2024,
Номер
15
Опубликована: Сен. 25, 2024
Notable
progress
has
been
made
in
"ferroptosis-based
nano
drug
delivery
systems
(NDDSs)"
over
the
past
11
years.
Despite
ongoing
absence
of
a
comprehensive
scientometric
overview
and
up-to-date
scientific
mapping
research,
especially
regarding
evolution,
critical
research
pathways,
current
landscape,
central
investigative
themes,
future
directions.
