IEEE Transactions on Molecular Biological and Multi-Scale Communications,
Год журнала:
2023,
Номер
10(1), С. 43 - 74
Опубликована: Дек. 4, 2023
Molecular
communication,
as
implied
by
its
name,
uses
molecules
information
carriers
for
communication
between
objects.
It
has
an
advantage
over
traditional
electromagnetic-wave-based
in
that
molecule-based
systems
could
be
biocompatible,
operable
challenging
environments,
and
energetically
undemanding.
Consequently,
they
are
envisioned
to
have
a
broad
range
of
applications,
such
the
Internet
Bio-Nano
Things,
targeted
drug
delivery,
agricultural
monitoring.
Despite
rapid
development
field,
with
increasing
number
theoretical
models
experimental
testbeds
established
researchers,
fundamental
aspect
field
often
been
sidelined,
namely,
nature
molecule
molecular
communication.
The
potential
exhibit
wide
properties,
making
them
require
drastically
different
treatments
when
being
modeled
experimented
upon.
Therefore,
this
paper,
we
delve
into
intricacies
commonly
used
molecules,
examining
their
physical
characteristics,
associated
systems,
applications
more
realistic
manner,
focusing
on
influence
own
properties.
Through
comprehensive
survey,
aim
offer
novel
yet
essential
perspective
thereby
bridging
current
gap
research
real-world
applications.
Molecules,
Год журнала:
2023,
Номер
28(18), С. 6624 - 6624
Опубликована: Сен. 14, 2023
Knowing
the
beneficial
aspects
of
nanomedicine,
scientists
are
trying
to
harness
applications
nanotechnology
in
diagnosis,
treatment,
and
prevention
diseases.
There
also
potential
uses
designing
medical
tools
processes
for
new
generation
scientists.
The
main
objective
conducting
this
research
review
is
gather
widespread
nanomedicine
under
one
heading
highlight
standard
practices
field.
Comprehensive
has
been
conducted
incorporate
latest
data
related
medicine
therapeutics
derived
from
acknowledged
scientific
platforms.
Nanotechnology
used
conduct
sensitive
procedures.
showing
successful
fields
diagnostics,
disease
regenerative
medicine,
gene
therapy,
dentistry,
oncology,
aesthetics
industry,
drug
delivery,
therapeutics.
A
thorough
association
cooperation
between
physicians,
clinicians,
researchers,
technologies
will
bring
forward
a
future
where
there
more
calculated,
outlined,
technically
programed
field
nanomedicine.
Advances
being
made
overcome
challenges
associated
with
application
due
pathophysiological
basis
This
highlights
multipronged
how
proving
health
industry.
need
minimize
health,
environmental,
ethical
concerns
linked
nanotechnology.
ACS Applied Nano Materials,
Год журнала:
2024,
Номер
7(15), С. 17151 - 17192
Опубликована: Июль 24, 2024
The
advancement
of
precision
medicine
in
modern
biomedicine
has
been
significantly
propelled
by
the
emergence
micro/nanorobots.
combination
micro/nanorobots
and
offers
unique
advantages
holds
attractive
potential
for
applications.
It
effectively
addresses
challenges
encountered
traditional
robots
areas
such
as
driving,
sensing,
intelligence
other
aspects,
especially
application
cancer
cardiovascular
diseases,
which
is
a
hot
field
interdisciplinary
research
recent
years.
This
review
succinctly
delineates
analyzes
advancements
First,
achievements
years
are
systematically
classified
introduced
from
four
perspectives:
manufacturing
design,
drive
control,
biomedical
degradation.
In
particular,
in-depth
discussions
were
conducted
regarding
solutions
each
stage.
Second,
based
on
latest
results
applications,
development
direction
industrial
applications
key
technical
aspects
that
need
to
be
paid
attention
emphasized.
Finally,
we
discuss
opportunities
future,
it
expected
will
become
more
sophisticated
capable
performing
multiple
medical
functions
tasks.
They
implemented
vivo
assist
doctors
diagnosing
treating
diseases.
shows
significant
medicine.
Advanced Functional Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Апрель 2, 2024
Abstract
Micro/nanorobots
with
active
movement
capabilities
provide
a
new
option
for
the
treatment
of
glioblastoma
(GBM).
However,
long
working
distance
intravenous
injection
and
protection
blood‐brain
barrier
can
prevent
micro/nanorobots
from
reaching
target
location.
Photodynamic
therapy
(PDT)
has
gradually
appeared
in
GBM
research.
The
limitation
penetrating
strength
light
source
will
nevertheless
hinder
application
range
PDT.
Herein,
magnetic
continuum
robot
(MCR)
to
deliver
optical
fibers
microrobots
combined
chemotherapy
PDT
is
used.
prepared
diatom
effectively
move
biological
fluids
upstream.
Vacuum
loading
improve
drug
efficiency.
photosensitizer
frustule
cavity
be
explosively
released
short
time
through
ultrasound.
chemotherapeutic
drugs
have
long‐term
pH‐sensitivity
release
characteristics.
In
vitro
cell
experiments
showed
that
administration
TMZ‐loaded
photosensitizer‐loaded
synergistic
effect.
model
demonstrated
an
MCR
fiber
drug‐loaded
microrobots.
This
enables
cross‐scale
delivery
deep
method
may
expand
selectivity
possibility
intracranial
Advanced Healthcare Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 7, 2024
Abstract
Biohybrid
micro/nanorobots
hold
a
great
potential
for
advancing
biomedical
research.
These
tiny
structures,
designed
to
mimic
biological
organisms,
offer
promising
method
targeted
drug
delivery,
tissue
engineering,
biosensing/imaging,
and
cancer
therapy,
among
other
applications.
The
integration
of
biology
robotics
opens
new
possibilities
minimally
invasive
surgeries
personalized
healthcare
solutions.
key
challenges
in
the
development
biohybrid
include
ensuring
biocompatibility,
addressing
manufacturing
scalability,
enhancing
navigation
localization
capabilities,
maintaining
stability
dynamic
environments,
navigating
regulatory
hurdles,
successfully
translating
these
innovative
technologies
into
clinical
Herein,
recent
advancements,
challenges,
future
perspectives
related
applications
are
described.
Indeed,
this
review
sheds
light
on
cutting‐edge
developments
field,
providing
researchers
with
an
updated
overview
current
realm
applications,
offering
insights
their
practical
Furthermore,
it
delves
advancements
field
micro/nanorobotics,
comprehensive
analysis
state‐of‐the‐art
field.
ACS Omega,
Год журнала:
2025,
Номер
10(6), С. 5214 - 5250
Опубликована: Фев. 4, 2025
In
light
of
the
ongoing
technological
transformation,
embracing
advancements
that
foster
shared
benefits
is
essential.
Nanorobots,
a
breakthrough
within
nanotechnology,
have
demonstrated
significant
potential
in
fields
such
as
medicine,
where
diagnostic
and
therapeutic
applications
are
primary
focus
areas.
This
review
provides
comprehensive
overview
robots,
their
evolving
role
medical
applications,
particularly
highlighting
use
nanorobots.
Various
design
strategies
operational
principles,
including
sensors,
actuators,
nanocontrollers,
discussed
based
on
prior
research.
Key
nanorobot
include
biomedical
imaging,
biosensing,
minimally
invasive
surgery,
targeted
drug
delivery,
each
utilizing
advanced
actuation
technologies
to
enhance
precision.
The
paper
further
examines
recent
progress
micro/nanorobot
addresses
important
considerations
for
future,
biocompatibility,
control,
navigation,
targeting,
safety,
ethical
implications.
offers
holistic
perspective
how
nanorobots
can
reshape
practices,
paving
way
precision
medicine
improved
patient
outcomes.
Advanced Materials Technologies,
Год журнала:
2024,
Номер
unknown
Опубликована: Май 16, 2024
Abstract
Biomimetic
and
biohybrid
micro/nano‐structures
involve
the
replication
creation
of
technologies,
structures,
materials
based
on
biological
systems
at
micrometer
nanometer
scale.
These
strategies
harness
natural
principles
to
develop
innovative
treatment
methods
advanced
microstructure
devices
for
noninvasive
therapies.
In
this
study,
a
detailed
overview
fabrication
processes,
magnetically
assisted
locomotive
techniques,
potential
applications
biomimetic
micro/nano‐machines
are
presented.
The
latest
advancements
in
actuated
such
as
annelid‐worm‐like
microswimmers,
jellyfish‐shaped
microparticles,
fish‐shaped
walnut‐shaped
micromotors
explored.
Additionally,
magnetic
systems,
including
sunflower
seed‐based
micro‐perforators,
nanomotors
extracted
from
bamboo
stem,
sperm
cell‐based
micromotors,
bacteria‐based
robots,
scaffold‐based
microrobots,
DNA‐based
microalgae‐based
red
blood
microswimmers
also
examined.
A
thorough
investigation
behavior
these
Newtonian
fluids,
featuring
cork‐screw
motion,
undulatory
surface
wrinkling
traveling
wave‐like
ciliary
stroke
motion
is
discussed.
Furthermore,
unprecedented
developed
using
minuscule
cervical
cancer
tetrapod
hybrid
tissue
regeneration
silk
fibroin
protein‐based
microscale
scaffolds,
doxorubicin
drug
delivery
mushroom‐based
microrobots
extensively
Nano Materials Science,
Год журнала:
2024,
Номер
unknown
Опубликована: Июнь 1, 2024
Micro/nanoscale
robots
(MNRs)
have
attracted
significant
interest
in
various
fields
because
of
their
flexible
design,
physically
controlled
maneuvering,
and
barrier
targeting.
The
execution
specific
functions
using
MNRs
relies
on
precise
propulsion
methods.
Among
the
diverse
techniques,
physical
is
widely
used
owing
to
its
noninvasive,
safe,
convenient
attributes.
This
review
provides
an
analysis
mechanisms
magnetic,
electric,
thermal,
ultrasound
presents
a
comprehensive
summary
structures,
movements,
applications
while
also
examining
advantages
shortcomings
associated
with
Finally,
challenges
perspectives
future
development
are
presented.
content
this
can
serve
as
multidisciplinary
science
reference
for
physicists,
bioengineers,
clinicians,
roboticists,
chemists
involved
pharmaceutical
design
clinical
therapy
research.
Engineered Regeneration,
Год журнала:
2023,
Номер
4(4), С. 411 - 426
Опубликована: Авг. 10, 2023
Micro-robots
(MRs)
are
miniature
machines
with
dimensions
smaller
than
1
mm
and
have
semi-
or
fully-autonomous
capabilities,
including
sensing,
decision-making,
performing
operations.
These
MRs
garnered
significant
attention
in
the
precision
medicine
personalized
treatment
field
due
to
their
ability
navigate
narrow
areas
of
human
body
non-desirable
fluid
flow.
Specifically,
actuated
by
a
mechanism
that
generates
propulsive
force
through
interaction
between
MRs'
actuation
modules
external
energy
sources
specific
direction.
This
driving
enables
precise
execution
medical
such
as
targeted
drug
delivery
minimally
invasive
surgeries.
Nonetheless,
currently
encounter
certain
challenges
clinical
practice,
reliance
on
sources,
short
lifespan,
difficulties
degradation
recovery
within
body.
article
aims
review
common
components
characteristics
for
modules,
propose
possible
solutions
address
current
challenges,
ultimately,
explore
desirable
structural
functional
composition
future
development
MRs.
Through
these
efforts,
this
hopes
provide
guidance
medicine.
