Optics & Laser Technology, Год журнала: 2023, Номер 164, С. 109494 - 109494
Опубликована: Апрель 21, 2023
Язык: Английский
Small, Год журнала: 2023, Номер 19(35)
Опубликована: Май 10, 2023
Advanced sensing devices, highly sensitive, and reliable in detecting ultralow concentrations of circulating biomarkers, are extremely desirable hold great promise for early diagnostics real-time progression monitoring diseases. Nowadays, the most commonly used clinical methods diagnosing biomarkers suffer from complicated procedures being time consumption. Here, a chip-based portable ultra-sensitive THz metasensor is reported by exploring quasi-bound states continuum (quasi-BICs) demonstrate its capability low-concentration analytes. The designed made split-ring resonator metasurface which supports magnetic dipole quasi-BIC combining functionalized gold nanoparticles (AuNPs) conjugated with specific antibody. Attributed to strong near-field enhancement near surface microstructure enabled quasi-BICs, light-analyte interactions greatly enhanced, thus device's sensitivity boosted significantly. system slope up 674 GHz/RIU, allowing repeatable resolving concentration C-reactive protein (CRP) Serum Amyloid A (SAA), respectively, down 1 pM. results touch range that cannot be achieved ordinary immunological assays alone, offering novel non-destructive rapid trace measured approach next-generation biomedical quantitative detection systems.
Язык: Английский
Процитировано
149
Nanophotonics, Год журнала: 2022, Номер 11(8), С. 1485 - 1514
Опубликована: Март 2, 2022
The terahertz (0.1-10 THz) range represents a fast-evolving research and industrial field. great interest for this portion of the electromagnetic spectrum, which lies between photonics electronics ranges, stems from unique disruptive sectors where radiation finds applications in, such as spectroscopy, quantum electronics, sensing wireless communications beyond 5G. Engineering propagation light has always proved to be an intrinsically difficult task long time it been bottleneck hindering full exploitation spectrum. Amongst different approaches that have proposed so far signal manipulation, implementation metamaterials most successful one, owing relative ease realisation, high efficiency spectral versatility. In review, we present latest developments in modulators based on metamaterials, while highlighting few selected key sensing, particularly benefitted these developments.
Язык: Английский
Процитировано
109
Photonics Research, Год журнала: 2023, Номер 12(2), С. 194 - 194
Опубликована: Дек. 4, 2023
The terahertz (THz) wave is at the intersection between photonics and electronics in electromagnetic spectrum. Since vibration mode of many biomedical molecules weak interaction inside fall THz regime, utilizing radiation as a signal source to operate substance information sensing has its unique advantages. Recently, metamaterial sensor (metasensor) greatly enhanced substances spectral selectivity on subwavelength scale. However, most past review articles have demonstrated metasensor terms their structures, applications, or materials. Until recently, with rapid development metasensing technologies, molecular paid much more attention platform metasensors. In this review, we comprehensively introduce for detecting not only featureless refractive index but also vibrational/chiral analytes. objectives are improve specificity either by chemical material-assisted analyte capture physical information. Later, boost absorption features certain frequency, resonant responses metasensors can be tuned vibrational modes target molecules, while frequency multiplexing techniques reviewed enhance broadband spectroscopic fingerprints. chiral summarized specific identification molecules. Finally, potential prospects next generation discussed. Compared metasensing, platforms accelerated material modification will lead greater impact advancement trace detection conformational dynamics biomolecules practical applications.
Язык: Английский
Процитировано
77
Biosensors, Год журнала: 2023, Номер 13(8), С. 759 - 759
Опубликована: Июль 26, 2023
In many fields, such as environmental monitoring, food safety, and medical diagnostics, the identification of organic compounds is essential. It crucial to create exceptionally sensitive selective sensors for detection in order safeguard environment human health. Due its outstanding electrical, mechanical, chemical characteristics, two-dimensional carbon substance graphene has recently attracted much attention use sensing applications. The purpose this research an material sensor made from substances like phenol, ethanol, methanol, chloroform, etc. high surface-to-volume ratio potent interactions with molecules, improves sensor's performance while metasurface structure enables design highly elements. suggested accurate at detecting a broad spectrum making it appropriate number creation potential have substantial impact on field increase safety food, medicine, environment. (GMOMS) was categorized into three types denoted GMOMS1, GMOMS2, GMOMS3 based specific application (GCP). GCP applied both CSRR CS surfaces. surface surrounding outer region CSRR. GMOMS3, surface. results show that all designs exhibit relative sensitivity, maximum values ranging 227 GHz/RIU achieved by GMOMS1 4318 GMOMS3. FOM range 2.038 RIU-1 GMOMS2 31.52 which considered ideal paper.
Язык: Английский
Процитировано
56
IEEE Sensors Journal, Год журнала: 2024, Номер 24(18), С. 28889 - 28896
Опубликована: Авг. 8, 2024
Язык: Английский
Процитировано
23
Optics & Laser Technology, Год журнала: 2024, Номер 183, С. 112345 - 112345
Опубликована: Дек. 17, 2024
Язык: Английский
Процитировано
21
Zeitschrift für Naturforschung A, Год журнала: 2025, Номер unknown
Опубликована: Апрель 7, 2025
Abstract This study presents the design and optimization of a graphene–gold–silver metasurface sensor for highly sensitive detection organic compounds in terahertz (THz) regime. By leveraging plasmonic properties gold silver combined with tunable electronic characteristics graphene, demonstrates enhanced molecular interaction improved performance. COMSOL Multiphysics simulations show high refractive index sensitivity up to value 810 GHzRIU −1 excellent resonance quality factor (Q) 11.197. The achieves limit (DL) as low 0.075 RIU dynamic range (DR) from 2.765 2.555, indicating exceptional broad applicability. Additionally, integration machine learning optimization, particularly Locally Weighted Linear Regression (LWLR), improves prediction accuracy, achieving R 2 near 1. results highlight sensor’s real-time, label-free capabilities, signal-to-noise ratio (SNR) 0.377. These findings demonstrate potential applications environmental monitoring, biomedical diagnostics, industrial control, offering significant advancement THz-based sensing technologies.
Язык: Английский
Процитировано
6
Measurement, Год журнала: 2025, Номер unknown, С. 117318 - 117318
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
2
IEEE Access, Год журнала: 2022, Номер 10, С. 53761 - 53776
Опубликована: Янв. 1, 2022
Terahertz (THz) radiation (0.1~10 THz) shows great potential in agricultural products detection, biomedical, and security inspection recent years. Machine learning methods are widely used to support the user demand of higher efficiency high prediction accuracy. The technological key challenges machine for THz spectroscopy image data preprocessing, reconstruction algorithms, qualitative quantitative analysis. In this paper, an exhaustive review related works detection imaging techniques presented. application combined with technology quality products, inspection, materials science highlighted. Challenges these applications addressed. development trend future perspectives also discussed.
Язык: Английский
Процитировано
63
TrAC Trends in Analytical Chemistry, Год журнала: 2022, Номер 158, С. 116888 - 116888
Опубликована: Дек. 13, 2022
Язык: Английский
Процитировано
47