Ultrasensitive Terahertz Biodetection Enabled by Quasi‐BIC‐Based Metasensors

Small, Journal Year: 2023, Volume and Issue: 19(35)

Published: May 10, 2023

Advanced sensing devices, highly sensitive, and reliable in detecting ultralow concentrations of circulating biomarkers, are extremely desirable hold great promise for early diagnostics real-time progression monitoring diseases. Nowadays, the most commonly used clinical methods diagnosing biomarkers suffer from complicated procedures being time consumption. Here, a chip-based portable ultra-sensitive THz metasensor is reported by exploring quasi-bound states continuum (quasi-BICs) demonstrate its capability low-concentration analytes. The designed made split-ring resonator metasurface which supports magnetic dipole quasi-BIC combining functionalized gold nanoparticles (AuNPs) conjugated with specific antibody. Attributed to strong near-field enhancement near surface microstructure enabled quasi-BICs, light-analyte interactions greatly enhanced, thus device's sensitivity boosted significantly. system slope up 674 GHz/RIU, allowing repeatable resolving concentration C-reactive protein (CRP) Serum Amyloid A (SAA), respectively, down 1 pM. results touch range that cannot be achieved ordinary immunological assays alone, offering novel non-destructive rapid trace measured approach next-generation biomedical quantitative detection systems.

Language: Английский

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Recent progress in terahertz metamaterial modulators

Nanophotonics, Journal Year: 2022, Volume and Issue: 11(8), P. 1485 - 1514

Published: March 2, 2022

The terahertz (0.1-10 THz) range represents a fast-evolving research and industrial field. great interest for this portion of the electromagnetic spectrum, which lies between photonics electronics ranges, stems from unique disruptive sectors where radiation finds applications in, such as spectroscopy, quantum electronics, sensing wireless communications beyond 5G. Engineering propagation light has always proved to be an intrinsically difficult task long time it been bottleneck hindering full exploitation spectrum. Amongst different approaches that have proposed so far signal manipulation, implementation metamaterials most successful one, owing relative ease realisation, high efficiency spectral versatility. In review, we present latest developments in modulators based on metamaterials, while highlighting few selected key sensing, particularly benefitted these developments.

Language: Английский

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Review on the terahertz metasensor: from featureless refractive index sensing to molecular identification

Photonics Research, Journal Year: 2023, Volume and Issue: 12(2), P. 194 - 194

Published: Dec. 4, 2023

The terahertz (THz) wave is at the intersection between photonics and electronics in electromagnetic spectrum. Since vibration mode of many biomedical molecules weak interaction inside fall THz regime, utilizing radiation as a signal source to operate substance information sensing has its unique advantages. Recently, metamaterial sensor (metasensor) greatly enhanced substances spectral selectivity on subwavelength scale. However, most past review articles have demonstrated metasensor terms their structures, applications, or materials. Until recently, with rapid development metasensing technologies, molecular paid much more attention platform metasensors. In this review, we comprehensively introduce for detecting not only featureless refractive index but also vibrational/chiral analytes. objectives are improve specificity either by chemical material-assisted analyte capture physical information. Later, boost absorption features certain frequency, resonant responses metasensors can be tuned vibrational modes target molecules, while frequency multiplexing techniques reviewed enhance broadband spectroscopic fingerprints. chiral summarized specific identification molecules. Finally, potential prospects next generation discussed. Compared metasensing, platforms accelerated material modification will lead greater impact advancement trace detection conformational dynamics biomolecules practical applications.

Language: Английский

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Designing a Graphene Metasurface Organic Material Sensor for Detection of Organic Compounds in Wastewater

Biosensors, Journal Year: 2023, Volume and Issue: 13(8), P. 759 - 759

Published: July 26, 2023

In many fields, such as environmental monitoring, food safety, and medical diagnostics, the identification of organic compounds is essential. It crucial to create exceptionally sensitive selective sensors for detection in order safeguard environment human health. Due its outstanding electrical, mechanical, chemical characteristics, two-dimensional carbon substance graphene has recently attracted much attention use sensing applications. The purpose this research an material sensor made from substances like phenol, ethanol, methanol, chloroform, etc. high surface-to-volume ratio potent interactions with molecules, improves sensor's performance while metasurface structure enables design highly elements. suggested accurate at detecting a broad spectrum making it appropriate number creation potential have substantial impact on field increase safety food, medicine, environment. (GMOMS) was categorized into three types denoted GMOMS1, GMOMS2, GMOMS3 based specific application (GCP). GCP applied both CSRR CS surfaces. surface surrounding outer region CSRR. GMOMS3, surface. results show that all designs exhibit relative sensitivity, maximum values ranging 227 GHz/RIU achieved by GMOMS1 4318 GMOMS3. FOM range 2.038 RIU-1 GMOMS2 31.52 which considered ideal paper.

Language: Английский

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Tri-band terahertz metamaterial absorber based on structural Ti₃C₂T_x MXene for enhanced sensing application

IEEE Sensors Journal, Journal Year: 2024, Volume and Issue: 24(18), P. 28889 - 28896

Published: Aug. 8, 2024

Language: Английский

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Design and experimental realization of triple-band filtering metamaterial in sub-terahertz band enabled by conductivity coupling response of two identical split rings

Optics & Laser Technology, Journal Year: 2024, Volume and Issue: 183, P. 112345 - 112345

Published: Dec. 17, 2024

Language: Английский

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Machine Learning and Application in Terahertz Technology: A Review on Achievements and Future Challenges

IEEE Access, Journal Year: 2022, Volume and Issue: 10, P. 53761 - 53776

Published: Jan. 1, 2022

Terahertz (THz) radiation (0.1~10 THz) shows great potential in agricultural products detection, biomedical, and security inspection recent years. Machine learning methods are widely used to support the user demand of higher efficiency high prediction accuracy. The technological key challenges machine for THz spectroscopy image data preprocessing, reconstruction algorithms, qualitative quantitative analysis. In this paper, an exhaustive review related works detection imaging techniques presented. application combined with technology quality products, inspection, materials science highlighted. Challenges these applications addressed. development trend future perspectives also discussed.

Language: Английский

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Recent progress in terahertz biosensors based on artificial electromagnetic subwavelength structure

TrAC Trends in Analytical Chemistry, Journal Year: 2022, Volume and Issue: 158, P. 116888 - 116888

Published: Dec. 13, 2022

Language: Английский

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Hybrid metasurface using graphene/graphitic carbon nitride heterojunctions for ultrasensitive terahertz biosensors with tunable energy band structure

Photonics Research, Journal Year: 2023, Volume and Issue: 11(5), P. 858 - 858

Published: March 8, 2023

Integrating novel materials is critical for the ultrasensitive, multi-dimensional detection of biomolecules in terahertz (THz) range. Few studies on THz biosensors have used semiconductive active layers with tunable energy band structures. In this study, we demonstrate three detecting casein molecules based hybridization metasurface graphitic carbon nitride, graphene, and heterojunction. We achieved low-concentration a 3.54 ng/mL limit sensing by observing degrees variations (frequency shift, transmission difference, phase difference). The favorable effect conductivity layer can be to explain internal mechanism. incorporation protein changes carrier concentration surface semiconductor via electrostatic doping as positively charged grows, which alters structure layer. measured results indicate that any distinguished directly resonance frequency, value, difference. With heterojunction, biosensor showed highest response among biosensors. Silvaco Atlas package was simulate samples’ transport benefits heterojunction sensor. simulation validated our proposed theoretical mechanism model. Our could provide approach metasurface-based ultrasensitive biosensing technologies.

Language: Английский

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Enhancing THz fingerprint detection on the planar surface of an inverted dielectric metagrating

Photonics Research, Journal Year: 2022, Volume and Issue: 10(12), P. 2836 - 2836

Published: Oct. 18, 2022

Terahertz (THz) molecular fingerprint sensing provides a powerful label-free tool for the detection of trace-amount samples. Due to weak light–matter interaction, various metallic or dielectric metasurfaces have been adopted enhance absorbance signals. However, they suffer from strong background damping complicated sample coating on patterned surfaces. Here, we propose an inverted metagrating and broadband THz trace analytes planar surface. Enhancement signal originates effects evanescent waves at interface, which are excited by multiplexed quasi-bound states in continuum (quasi-BICs). One can evenly boost near-field intensities within tuning asymmetry parameter quasi-BIC modes. The multiplexing mechanism is demonstrated manipulating incident angle excitation thickness waveguide layer. Compared conventional approach, peak value dramatically elevated, largest enhancement time 330. Our work gives promising way facilitate metasensing surface will inspire universal spectral analysis with different physical morphologies.

Language: Английский

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