Asian Journal of Organic Chemistry,
Год журнала:
2023,
Номер
12(11)
Опубликована: Сен. 12, 2023
Abstract
An
efficient
synthesis
of
a
variety
3‐difluoroalkyl
quinoxalin‐2(1
H
)‐ones
via
photoredox‐catalyzed
three‐component
reaction
between
)‐ones,
vinylarenes,
with
inexpensive
and
easily
accessible
difluoromethyltriphenyl
phosphonium
bromide
salt
as
the
difluoromethylated
reagent
is
described.
This
protocol
shows
excellent
reactivity,
providing
wide
range
difluoroalkyl‐substituted
in
moderate
to
yields
under
mild
conditions.
A
difluoroalkyl
radical
intermediate
was
involved
this
transformation.
European Journal of Organic Chemistry,
Год журнала:
2023,
Номер
26(36)
Опубликована: Авг. 25, 2023
Abstract
A
strategy
for
the
synthesis
of
diverse
protected
α‐monofluoro‐γ‐amino
acid
derivatives
has
been
developed.
This
reaction
assembles
a
simple
enamide,
quinoxalin‐2(1
H
)‐one,
and
diethyl
2‐bromo‐2‐fluoromalonate
through
three‐component
driven
by
visible
light.
The
advantages
this
protocol
include
simplicity
its
operation,
mild
conditions,
high
functional
group
tolerance,
applicability
to
wide
variety
substrates.
fluorine‐containing
amino
derivative
significant
value
potential
applications
in
medicinal
chemistry
chemical
biology.
Molecules,
Год журнала:
2023,
Номер
28(17), С. 6356 - 6356
Опубликована: Авг. 30, 2023
In
this
mini-review,
we
present
our
concepts
for
designing
multicomponent
reactions
with
reference
to
a
series
of
sequential
radical
that
have
developed.
Radical
are
well
suited
the
design
due
their
high
functional
group
tolerance
and
low
solvent
sensitivity.
We
focused
on
photolysis
interelement
compounds
heteroatom–heteroatom
single
bond,
which
readily
generates
heteroatom-centered
radicals,
studied
photoinduced
addition
unsaturated
compounds.
First,
background
is
described,
basic
methodology
construction
explained.
Next,
examples
involving
two
one
compound
presented,
as
Furthermore,
intramolecular
cyclization
processes
described.
Chinese Journal of Chemistry,
Год журнала:
2024,
Номер
42(13), С. 1481 - 1486
Опубликована: Март 7, 2024
Comprehensive
Summary
Organic
difluoroboron
complexes
are
a
kind
of
potential
platforms
for
wide
range
applications
owing
to
their
excellent
photophysical
properties.
Herein,
we
have
explored
simple
and
direct
synthesis
methodology
library
N
,
O
‐bidentate
from
quinoxalin‐2(1
H
)‐ones
ketones
in
one
shot.
The
properties
the
generated
were
evaluated
application
these
compounds
on
subcellular
imaging
was
also
explored.
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
22(29), С. 5924 - 5929
Опубликована: Янв. 1, 2024
A
transition-metal-
and
photocatalyst-free
photochemical
acylation
strategy
driven
by
the
photoexcitation
of
an
electron
donor–acceptor
(EDA)
complex
has
been
developed.
Reaction Chemistry & Engineering,
Год журнала:
2024,
Номер
10(3), С. 500 - 510
Опубликована: Дек. 20, 2024
Multicomponent
reactions
(MCRs)
have
become
excellent
tools
for
synthesizing
complex
and
high-value
molecules.
This
minireview
highlights
recent
progresses
in
MCRs
classified
by
the
type
of
catalysts
to
offer
a
better
deeper
understanding.
Asian Journal of Organic Chemistry,
Год журнала:
2023,
Номер
12(11)
Опубликована: Сен. 12, 2023
Abstract
An
efficient
synthesis
of
a
variety
3‐difluoroalkyl
quinoxalin‐2(1
H
)‐ones
via
photoredox‐catalyzed
three‐component
reaction
between
)‐ones,
vinylarenes,
with
inexpensive
and
easily
accessible
difluoromethyltriphenyl
phosphonium
bromide
salt
as
the
difluoromethylated
reagent
is
described.
This
protocol
shows
excellent
reactivity,
providing
wide
range
difluoroalkyl‐substituted
in
moderate
to
yields
under
mild
conditions.
A
difluoroalkyl
radical
intermediate
was
involved
this
transformation.
