Nickel-Catalyzed Reductive Cyanation of Aryl Halides and Epoxides with Cyanogen Bromide DOI Creative Commons

Yujuan Wu,

Chen Ma, Muhammad Bılal

и другие.

Molecules, Год журнала: 2024, Номер 29(24), С. 6016 - 6016

Опубликована: Дек. 20, 2024

Nitriles are valuable compounds because they have widespread applications in organic chemistry. This report details the nickel-catalyzed reductive cyanation of aryl halides and epoxides with cyanogen bromide for synthesis nitriles. robust protocol underscores practicality using a commercially available cost-effective reagent. A variety featuring diverse functional groups, such as -TMS, -Bpin, -OH, -NH2, -CN, -CHO, were successfully converted into nitriles moderate-to-good yields. Moreover, syntheses at gram-scale application late-stage natural products drugs reinforces its potentiality.

Язык: Английский

Nickel-catalysed chelation-assisted reductive defluorinative sulfenylation of trifluoropropionic acid derivatives DOI
Yu‐Qiu Guan,

Jia-Fan Qiao,

Yu‐Feng Liang

и другие.

Chemical Communications, Год журнала: 2024, Номер 60(17), С. 2405 - 2408

Опубликована: Янв. 1, 2024

Nickel-catalysed chelation-assisted reductive cross-coupling of trifluoropropanamides/esters with disulfides to afford thioacrylamides/esters high E selectivity, involving triple C–F bond cleavage.

Язык: Английский

Процитировано

4

Nickel‐Catalyzed Synthesis of Thioesters from Amides and Disulfides DOI
Wenpeng Mai, Yu Zhao,

Mingxiu Lv

и другие.

European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(12)

Опубликована: Фев. 8, 2024

Abstract A novel nickel‐catalyzed practical and simple synthesis of thioesters from amides disulfides has been developed. Diverse substituted aromatic are capable coupling with diaryl or dialkyl via C−N/S−S bonds cleavage to produce the desirable in moderate good yields. This procedure features cheap metals, easily preparative substrates, providing a access variety without toxic thiols CO gas.

Язык: Английский

Процитировано

4

Effect of π-Linkages in Covalent Organic Framework-Catalyzed Light-Harvesting Thioesterification Reaction DOI
Ayan Jati,

Durba Chanda,

Biplab Maji

и другие.

ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown

Опубликована: Фев. 24, 2025

Covalent organic frameworks (COFs) serve as an outstanding platform for heterogeneous photocatalysis. We synthesized two analogous pyrene-based two-dimensional COFs with π-conjugated networks, one linked by C═N bonds and the other C═C bonds, through Schiff base Knoevenagel condensation reactions, respectively. investigated impact of these linkages on photocatalytic activity COFs, using visible-light-mediated thioesterification a model reaction. It was found that olefin-linkage COF outperformed imine-linkage photocatalyst. The developed protocol demonstrated broad substrate scope, including 35 diverse carboxylic acids, 14 drug molecules, several disulfide coupling partners, achieving up to 95% yield thioesters. practical utility this strategy is further its successful application in gram-scale reactions. photocatalyst robust successfully reused multiple cycles without any loss catalytic activity. backbone facilitated enhanced electron transfer upon light irradiation, enabling cross-coupling acid reductive cycle.

Язык: Английский

Процитировано

0

Room temperature, metal-free, CDI-promoted, ex-situ protocol for S-methyl thioester synthesis DOI Creative Commons
Manisha Patel, Vandana Sharma, Rupali S. Chavan

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Май 27, 2025

Язык: Английский

Процитировано

0

Nickel-catalysed highly regioselective synthesis of β-acyl naphthalenes under reductive conditions DOI

Yujuan Wu,

Chen Ma,

Jia-Fan Qiao

и другие.

Chemical Communications, Год журнала: 2024, Номер 60(44), С. 5723 - 5726

Опубликована: Янв. 1, 2024

A nickel-catalysed reductive ring-opening reaction of 7-oxabenzonorbornadienes with acyl chlorides as the electrophilic coupling partner was developed, generating β-acyl naphthalene unique product without any α iso.

Язык: Английский

Процитировано

2

N-Alkoxyphthalimides as Nitrogen Electrophiles to Construct C–N Bonds via Reductive Cross-Coupling DOI
Kang Wu,

Tian‐Zhang Wang,

Chao‐Peng Zhang

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(14), С. 10004 - 10011

Опубликована: Июнь 27, 2024

-Alkoxyphthalimides, one kind of phthalimide derivative, have great importance in synthesis, mainly used as free radical precursors. While the unit, for a long time, was treated part waste stream. Construction C-N bonds has always been hot spot, especially reductive cross-coupling. Herein, nickel-catalyzed cross-coupling reaction

Язык: Английский

Процитировано

2

Amide and peptide synthesis via nickel-catalyzed cross-electrophile coupling DOI Creative Commons

Xing-Bang Liu,

Zhenqi Wang, Yanjie Yang

и другие.

Cell Reports Physical Science, Год журнала: 2024, Номер unknown, С. 102248 - 102248

Опубликована: Окт. 1, 2024

Язык: Английский

Процитировано

2

Recent Advances in Visible Light Photocatalytic and Transition Metal-Catalyzed Synthesis of Disulfide Compounds DOI
Jia‐Lin Tu

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Reviewing photocatalytic and metal-catalyzed disulfide synthesis, 2021–2024, emphasizes efficiency, selectivity, sustainability for drug material science.

Язык: Английский

Процитировано

0

Nickel-Catalyzed Reductive Cyanation of Aryl Halides and Epoxides with Cyanogen Bromide DOI Creative Commons

Yujuan Wu,

Chen Ma, Muhammad Bılal

и другие.

Molecules, Год журнала: 2024, Номер 29(24), С. 6016 - 6016

Опубликована: Дек. 20, 2024

Nitriles are valuable compounds because they have widespread applications in organic chemistry. This report details the nickel-catalyzed reductive cyanation of aryl halides and epoxides with cyanogen bromide for synthesis nitriles. robust protocol underscores practicality using a commercially available cost-effective reagent. A variety featuring diverse functional groups, such as -TMS, -Bpin, -OH, -NH2, -CN, -CHO, were successfully converted into nitriles moderate-to-good yields. Moreover, syntheses at gram-scale application late-stage natural products drugs reinforces its potentiality.

Язык: Английский

Процитировано

0