Advanced Functional Materials,
Год журнала:
2023,
Номер
34(31)
Опубликована: Дек. 6, 2023
Abstract
The
utilization
of
gallium
(Ga)‐based
liquid
metals
(LMs)
as
functional
materials
in
bioelectronics
has
been
extensively
explored
over
the
past
decade
a
key
to
stimulation
biological
systems
and
recording
signals.
motivation
behind
this
class
electronics
is
driven
by
opportunities
exploit
mechanical
properties
similar
tissues.
These
bioelectronic
devices
are
required
maintain
functionality
under
deformation
and,
especially
for
implantable
applications,
should
interface
with
tissues
minimally
invasive
manner.
LMs
attractive
such
applications
due
their
ability
deform
while
retaining
electrical
conductivity.
Furthermore,
unlike
most
liquids
that
form
droplets
minimize
surface
energy,
ultrathin
solid‐state
oxide
layer
on
outer
enables
them
be
shaped
specific
3D
patterns.
Unlike
mercury,
Ga‐based
considered
biocompatible
low
toxicity
vapor
pressure,
highlighting
potential
advantageous
bioelectronics.
This
review
comprehensively
presents
fundamental
aspects
these
materials,
focus
effectiveness
stimulating
tissues,
well
diverse
soft
stretchable
electrodes
Additionally,
investigates
additional
strategies
aimed
at
driving
future
advancements
field.
Advanced Materials,
Год журнала:
2023,
Номер
35(29)
Опубликована: Март 31, 2023
Advances
in
emerging
technologies
for
wireless
collection
and
the
timely
analysis
of
various
information
captured
by
wearable
devices
are
growing
interest.
Herein,
a
crosslinked
ionic
hydrogel
prepared
facile
photocuring
process
is
proposed,
which
allows
to
be
further
incorporated
into
two
integrated
systems
pressure
monitoring
applications.
The
device
exhibits
simplified
structure
effectively
sharing
functional
layers,
rather
than
conventional
separate
combinations,
offering
salient
performance
iontronic
sensing
electrochromic
properties
simultaneously
quantify
visualize
pressure.
developed
smart
patch
system
demonstrated
monitor
physiological
signals
real-time
utilizing
user
interface
remote
portable
equipment
with
Bluetooth
protocol
on-site
displays.
Moreover,
passive
based
on
magnetic
coupling
effect
designed,
can
operate
free
from
battery
acquire
multiple
information.
It
envisioned
that
strategies
would
hold
enormous
potential
flexible
electronics,
versatile
platforms,
on-body
networks.
Advanced Materials,
Год журнала:
2023,
Номер
unknown
Опубликована: Авг. 28, 2023
The
rise
of
flexible
and
stretchable
electronics
has
revolutionized
biosensor
techniques
for
probing
biological
systems.
Particularly,
electrochemical
sensors
(FSECSs)
enable
the
in
situ
quantification
numerous
biochemical
molecules
different
entities
owing
to
their
exceptional
sensitivity,
fast
response,
easy
miniaturization.
Over
past
decade,
fabrication
application
FSECSs
have
significantly
progressed.
This
review
highlights
key
developments
electrode
functionalization.
It
delves
into
sensing
various
biomarkers,
including
metabolites,
electrolytes,
signaling
molecules,
neurotransmitters
from
systems,
encompassing
outer
epidermis,
tissues/organs
vitro
vivo,
living
cells.
Finally,
considering
preparation
applications,
current
challenges
future
opportunities
are
discussed.
Chemical Reviews,
Год журнала:
2023,
Номер
123(19), С. 11488 - 11558
Опубликована: Сен. 25, 2023
The
eye
contains
a
complex
network
of
physiological
information
and
biomarkers
for
monitoring
disease
managing
health,
ocular
devices
can
be
used
to
effectively
perform
point-of-care
diagnosis
management.
This
comprehensive
review
describes
the
target
various
diseases,
including
ophthalmic
metabolic
neurological
based
on
anatomical
background
eye.
also
includes
recent
technologies
utilized
in
eye-wearable
medical
latest
trends
wearable
devices,
specifically
smart
contact
lenses
purpose
After
introducing
other
such
as
retinal
prosthesis,
we
further
discuss
current
challenges
potential
possibilities
lenses.
Advanced Materials,
Год журнала:
2024,
Номер
36(27)
Опубликована: Апрель 23, 2024
Wireless
and
wearable
sensors
attract
considerable
interest
in
personalized
healthcare
by
providing
a
unique
approach
for
remote,
noncontact,
continuous
monitoring
of
various
health-related
signals
without
interference
with
daily
life.
Recent
advances
wireless
technologies
have
promoted
practical
applications
due
to
their
significantly
improved
characteristics,
such
as
reduction
size
thickness,
enhancement
flexibility
stretchability,
conformability
the
human
body.
Currently,
most
researches
focus
on
active
materials
structural
designs
sensors,
just
few
exceptions
reflecting
data
transmission.
This
review
provides
comprehensive
overview
state-of-the-art
related
studies
empowering
sensors.
The
emerging
functional
nanomaterials
utilized
designing
modules
are
highlighted,
which
include
metals,
carbons,
MXenes.
Additionally,
outlines
system-level
integration
flexible
spanning
from
novel
design
strategies
enhanced
efficient
transmitting
wirelessly.
Furthermore,
introduces
representative
remote
noninvasive
physiological
through
on-skin
implantable
sensing
systems.
Finally,
challenges,
perspectives,
unprecedented
opportunities
discussed.
Abstract
Since
the
beginning
of
human
history,
demand
for
effective
healthcare
systems
diagnosis
and
treatment
health
problems
has
grown
steadily.
However,
traditional
centralized
requires
hospital
visits,
making
in‐time
long‐term
challenging.
Bioelectronics
shown
potential
in
patient‐friendly
owing
to
rapid
advances
diverse
fields
biology
electronics.
In
particular,
wearable
implantable
bioelectronics
have
emerged
as
an
alternative
or
adjunct
conventional
healthcare.
To
develop
into
next‐generation
systems,
however,
custom
designs
biological
targets
with
a
deepened
understanding
intrinsic
features
target
are
essential.
addition,
bioelectronic
must
be
designed
eco‐friendly
sustainable
this
review,
integrated
nanoarchitectonics
smart
technology
described.
For
in‐depth
guidelines
target‐tailored
design,
we
discuss
target‐specific
considerations
relevant
key
parameters
representative
examples.
image
Nature Communications,
Год журнала:
2024,
Номер
15(1)
Опубликована: Апрель 2, 2024
Abstract
Tears
have
emerged
as
a
promising
alternative
to
blood
for
diagnosing
diabetes.
Despite
increasing
attempts
measure
tear
glucose
using
smart
contact
lenses,
the
controversy
surrounding
correlation
between
and
still
limits
clinical
usage
of
tears.
Herein,
we
present
an
in-depth
investigation
wireless
soft
lens
continuous
monitoring
glucose.
This
is
capable
quantitatively
levels
in
basal
tears
excluding
effect
reflex
which
might
weaken
relationship
with
Furthermore,
this
can
provide
unprecedented
level
data
acquisition
at
sub-minute
intervals.
These
advantages
allow
precise
estimation
lag
time,
enabling
establishment
concept
called
‘personalized
time’.
demonstration
considers
individual
differences
successfully
applied
both
non-diabetic
diabetic
humans,
well
animal
models,
resulting
high
correlation.
ACS Nano,
Год журнала:
2024,
Номер
18(9), С. 6817 - 6844
Опубликована: Фев. 26, 2024
The
eye
contains
a
wealth
of
physiological
information
and
offers
suitable
environment
for
noninvasive
monitoring
diseases
via
smart
contact
lens
sensors.
Although
extensive
research
efforts
recently
have
been
undertaken
to
develop
sensors,
they
are
still
in
an
early
stage
being
utilized
as
intelligent
wearable
sensing
platform
various
biophysical/chemical
conditions.
In
this
review,
we
provide
general
introduction
lenses
that
developed
disease
therapy.
First,
different
biomarkers
available
from
the
ocular
summarized,
including
both
physical
chemical
biomarkers,
followed
by
commonly
used
materials,
manufacturing
processes,
characteristics
lenses.
Smart
eye-drug
delivery
with
advancing
technologies
achieve
more
efficient
treatments
then
introduced
well
latest
developments
diagnosis.
Finally,
sensor
communication
antimicrobial
other
emerging
bioapplications
also
discussed
challenges
prospects
future
development
Chemical Reviews,
Год журнала:
2024,
Номер
124(5), С. 2205 - 2280
Опубликована: Фев. 21, 2024
Advances
in
soft
materials,
miniaturized
electronics,
sensors,
stimulators,
radios,
and
battery-free
power
supplies
are
resulting
a
new
generation
of
fully
implantable
organ
interfaces
that
leverage
volumetric
reduction
mechanics
by
eliminating
electrochemical
storage.
This
device
class
offers
the
ability
to
provide
high-fidelity
readouts
physiological
processes,
enables
stimulation,
allows
control
over
organs
realize
therapeutic
diagnostic
paradigms.
Driven
seamless
integration
with
connected
infrastructure,
these
devices
enable
personalized
digital
medicine.
Key
advances
carefully
designed
material,
electrophysical,
electrochemical,
electromagnetic
systems
form
implantables
mechanical
properties
closely
matched
target
deliver
functionality
supports
sensors
stimulators.
The
elimination
operation,
anywhere
from
acute,
lifetimes
matching
subject
physical
dimensions
imperceptible
operation.
review
provides
comprehensive
overview
basic
building
blocks
related
topics
such
as
implantation,
delivery,
sterilization,
user
acceptance.
State
art
examples
categorized
system
an
outlook
interconnection
advanced
strategies
for
computation
leveraging
consistent
influx
elevate
this
current
battery-powered
is
highlighted.
Advanced Science,
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 3, 2024
Early-stage
disease
detection,
particularly
in
Point-Of-Care
(POC)
wearable
formats,
assumes
pivotal
role
advancing
healthcare
services
and
precision-medicine.
Public
benefits
of
early
detection
extend
beyond
cost-effectively
promoting
outcomes,
to
also
include
reducing
the
risk
comorbid
diseases.
Technological
advancements
enabling
POC
biomarker
recognition
empower
discovery
new
markers
for
various
health
conditions.
Integration
wearables
with
intelligent
frameworks
represents
ground-breaking
innovations
automation
operations,
conducting
advanced
large-scale
data
analysis,
generating
predictive
models,
facilitating
remote
guided
clinical
decision-making.
These
substantially
alleviate
socioeconomic
burdens,
creating
a
paradigm
shift
diagnostics,
revolutionizing
medical
assessments
technology
development.
This
review
explores
critical
topics
recent
progress
development
1)
systems
solutions
physiological
monitoring,
as
well
2)
discussing
current
trends
adoption
smart
technologies
within
settings
developing
biological
assays,
ultimately
3)
exploring
utilities
platforms
discovery.
Additionally,
translation
from
research
labs
broader
applications.
It
addresses
associated
risks,
biases,
challenges
widespread
Artificial
Intelligence
(AI)
integration
diagnostics
systems,
while
systematically
outlining
potential
prospects,
challenges,
opportunities.