Incorporating Wireless Strategies to Wearable Devices Enabled by a Photocurable Hydrogel for Monitoring Pressure Information

Advanced Materials, Journal Year: 2023, Volume and Issue: 35(29)

Published: March 31, 2023

Advances in emerging technologies for wireless collection and the timely analysis of various information captured by wearable devices are growing interest. Herein, a crosslinked ionic hydrogel prepared facile photocuring process is proposed, which allows to be further incorporated into two integrated systems pressure monitoring applications. The device exhibits simplified structure effectively sharing functional layers, rather than conventional separate combinations, offering salient performance iontronic sensing electrochromic properties simultaneously quantify visualize pressure. developed smart patch system demonstrated monitor physiological signals real-time utilizing user interface remote portable equipment with Bluetooth protocol on-site displays. Moreover, passive based on magnetic coupling effect designed, can operate free from battery acquire multiple information. It envisioned that strategies would hold enormous potential flexible electronics, versatile platforms, on-body networks.

Language: Английский

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Biosensors for healthcare: current and future perspectives

Trends in biotechnology, Journal Year: 2022, Volume and Issue: 41(3), P. 374 - 395

Published: Dec. 23, 2022

Language: Английский

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Flexible and Stretchable Electrochemical Sensors for Biological Monitoring

Advanced Materials, Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 28, 2023

The rise of flexible and stretchable electronics has revolutionized biosensor techniques for probing biological systems. Particularly, electrochemical sensors (FSECSs) enable the in situ quantification numerous biochemical molecules different entities owing to their exceptional sensitivity, fast response, easy miniaturization. Over past decade, fabrication application FSECSs have significantly progressed. This review highlights key developments electrode functionalization. It delves into sensing various biomarkers, including metabolites, electrolytes, signaling molecules, neurotransmitters from systems, encompassing outer epidermis, tissues/organs vitro vivo, living cells. Finally, considering preparation applications, current challenges future opportunities are discussed.

Language: Английский

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Wireless Technologies in Flexible and Wearable Sensing: From Materials Design, System Integration to Applications

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(27)

Published: April 23, 2024

Wireless and wearable sensors attract considerable interest in personalized healthcare by providing a unique approach for remote, noncontact, continuous monitoring of various health-related signals without interference with daily life. Recent advances wireless technologies have promoted practical applications due to their significantly improved characteristics, such as reduction size thickness, enhancement flexibility stretchability, conformability the human body. Currently, most researches focus on active materials structural designs sensors, just few exceptions reflecting data transmission. This review provides comprehensive overview state-of-the-art related studies empowering sensors. The emerging functional nanomaterials utilized designing modules are highlighted, which include metals, carbons, MXenes. Additionally, outlines system-level integration flexible spanning from novel design strategies enhanced efficient transmitting wirelessly. Furthermore, introduces representative remote noninvasive physiological through on-skin implantable sensing systems. Finally, challenges, perspectives, unprecedented opportunities discussed.

Language: Английский

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Smart Contact Lenses as Wearable Ophthalmic Devices for Disease Monitoring and Health Management

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(19), P. 11488 - 11558

Published: Sept. 25, 2023

The eye contains a complex network of physiological information and biomarkers for monitoring disease managing health, ocular devices can be used to effectively perform point-of-care diagnosis management. This comprehensive review describes the target various diseases, including ophthalmic metabolic neurological based on anatomical background eye. also includes recent technologies utilized in eye-wearable medical latest trends wearable devices, specifically smart contact lenses purpose After introducing other such as retinal prosthesis, we further discuss current challenges potential possibilities lenses.

Language: Английский

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Wearable and implantable bioelectronics as eco‐friendly and patient‐friendly integrated nanoarchitectonics for next‐generation smart healthcare technology

EcoMat, Journal Year: 2023, Volume and Issue: 5(8)

Published: May 8, 2023

Abstract Since the beginning of human history, demand for effective healthcare systems diagnosis and treatment health problems has grown steadily. However, traditional centralized requires hospital visits, making in‐time long‐term challenging. Bioelectronics shown potential in patient‐friendly owing to rapid advances diverse fields biology electronics. In particular, wearable implantable bioelectronics have emerged as an alternative or adjunct conventional healthcare. To develop into next‐generation systems, however, custom designs biological targets with a deepened understanding intrinsic features target are essential. addition, bioelectronic must be designed eco‐friendly sustainable this review, integrated nanoarchitectonics smart technology described. For in‐depth guidelines target‐tailored design, we discuss target‐specific considerations relevant key parameters representative examples. image

Language: Английский

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Smart Contact Lenses for Healthcare Monitoring and Therapy

ACS Nano, Journal Year: 2024, Volume and Issue: 18(9), P. 6817 - 6844

Published: Feb. 26, 2024

The eye contains a wealth of physiological information and offers suitable environment for noninvasive monitoring diseases via smart contact lens sensors. Although extensive research efforts recently have been undertaken to develop sensors, they are still in an early stage being utilized as intelligent wearable sensing platform various biophysical/chemical conditions. In this review, we provide general introduction lenses that developed disease therapy. First, different biomarkers available from the ocular summarized, including both physical chemical biomarkers, followed by commonly used materials, manufacturing processes, characteristics lenses. Smart eye-drug delivery with advancing technologies achieve more efficient treatments then introduced well latest developments diagnosis. Finally, sensor communication antimicrobial other emerging bioapplications also discussed challenges prospects future development

Language: Английский

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In-depth correlation analysis between tear glucose and blood glucose using a wireless smart contact lens

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: April 2, 2024

Abstract Tears have emerged as a promising alternative to blood for diagnosing diabetes. Despite increasing attempts measure tear glucose using smart contact lenses, the controversy surrounding correlation between and still limits clinical usage of tears. Herein, we present an in-depth investigation wireless soft lens continuous monitoring glucose. This is capable quantitatively levels in basal tears excluding effect reflex which might weaken relationship with Furthermore, this can provide unprecedented level data acquisition at sub-minute intervals. These advantages allow precise estimation lag time, enabling establishment concept called ‘personalized time’. demonstration considers individual differences successfully applied both non-diabetic diabetic humans, well animal models, resulting high correlation.

Language: Английский

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Revolutionary Point‐of‐Care Wearable Diagnostics for Early Disease Detection and Biomarker Discovery through Intelligent Technologies

Advanced Science, Journal Year: 2024, Volume and Issue: unknown

Published: July 3, 2024

Early-stage disease detection, particularly in Point-Of-Care (POC) wearable formats, assumes pivotal role advancing healthcare services and precision-medicine. Public benefits of early detection extend beyond cost-effectively promoting outcomes, to also include reducing the risk comorbid diseases. Technological advancements enabling POC biomarker recognition empower discovery new markers for various health conditions. Integration wearables with intelligent frameworks represents ground-breaking innovations automation operations, conducting advanced large-scale data analysis, generating predictive models, facilitating remote guided clinical decision-making. These substantially alleviate socioeconomic burdens, creating a paradigm shift diagnostics, revolutionizing medical assessments technology development. This review explores critical topics recent progress development 1) systems solutions physiological monitoring, as well 2) discussing current trends adoption smart technologies within settings developing biological assays, ultimately 3) exploring utilities platforms discovery. Additionally, translation from research labs broader applications. It addresses associated risks, biases, challenges widespread Artificial Intelligence (AI) integration diagnostics systems, while systematically outlining potential prospects, challenges, opportunities.

Language: Английский

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Wireless Battery-free and Fully Implantable Organ Interfaces

Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(5), P. 2205 - 2280

Published: Feb. 21, 2024

Advances in soft materials, miniaturized electronics, sensors, stimulators, radios, and battery-free power supplies are resulting a new generation of fully implantable organ interfaces that leverage volumetric reduction mechanics by eliminating electrochemical storage. This device class offers the ability to provide high-fidelity readouts physiological processes, enables stimulation, allows control over organs realize therapeutic diagnostic paradigms. Driven seamless integration with connected infrastructure, these devices enable personalized digital medicine. Key advances carefully designed material, electrophysical, electrochemical, electromagnetic systems form implantables mechanical properties closely matched target deliver functionality supports sensors stimulators. The elimination operation, anywhere from acute, lifetimes matching subject physical dimensions imperceptible operation. review provides comprehensive overview basic building blocks related topics such as implantation, delivery, sterilization, user acceptance. State art examples categorized system an outlook interconnection advanced strategies for computation leveraging consistent influx elevate this current battery-powered is highlighted.

Language: Английский

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