Graphical Abstract: Angew. Chem. Int. Ed. 50/2023 DOI Open Access
Zhonglong Zhao, Jiangwei Zhang, Qin Wang

и другие.

Angewandte Chemie International Edition, Год журнала: 2023, Номер 62(50)

Опубликована: Дек. 6, 2023

An s-block potassium

Язык: Английский

Selenium chemistry for spatio-selective peptide and protein functionalization DOI
Zhenguang Zhao, Shay Laps, Jacob S. Gichtin

и другие.

Nature Reviews Chemistry, Год журнала: 2024, Номер 8(3), С. 211 - 229

Опубликована: Фев. 22, 2024

Язык: Английский

Процитировано

18
Therapeutic stapled peptides: Efficacy and molecular targets DOI Creative Commons

Yulei Li,

Ming‐Hao Wu,

Yinxue Fu

и другие.

Pharmacological Research, Год журнала: 2024, Номер 203, С. 107137 - 107137

Опубликована: Март 23, 2024

Peptide stapling, by employing a stable, preformed alpha-helical conformation, results in the production of peptides with improved membrane permeability and enhanced proteolytic stability, compared to original peptides, provides an effective solution accelerate rapid development peptide drugs. Various reviews present stapling chemistries, anchoring residues one- or two-component cyclization, however, therapeutic stapled have not been systematically summarized, especially focusing on various disease-related targets. This review highlights latest advances drug facilitated application technology, including different techniques, synthetic accessibility, applicability biological targets, potential for solving problems, as well current status development. Stapled candidates classified analysed mainly receptor- ligand-based design against diseases, cancer, infectious inflammation, diabetes. is expected provide comprehensive reference rational diseases targets facilitate pharmacokinetic properties.

Язык: Английский

Процитировано

16
A novel MoS2/GA electrode based on hybrid capacitive deionization technology for ion removal in polypeptide solution DOI
Hongliang Li, Zhengliang Gong, Dongya Ma

и другие.

Separation and Purification Technology, Год журнала: 2025, Номер unknown, С. 132658 - 132658

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Evaluation of selenocysteine contents in Se-enriched yogurt by Utilizing online post column derivative − High-Performance liquid chromatography DOI

Witchapol Thosaikham,

Anut Chantiratikul,

Kunlanan Wongtawarat

и другие.

Microchemical Journal, Год журнала: 2024, Номер 207, С. 111872 - 111872

Опубликована: Окт. 10, 2024

Язык: Английский

Процитировано

1
Synthetic electrochemistry for peptides DOI
Yohei Okada, Kazuhiro Chiba

Current Opinion in Electrochemistry, Год журнала: 2024, Номер 45, С. 101469 - 101469

Опубликована: Март 7, 2024

Язык: Английский

Процитировано

1
Stabilization of 310-Helices in Macrocycles Using Dominant Rotor Methodology DOI

Martynas J. Širvinskas,

George J. Saunders,

Monica Mitrache

и другие.

Journal of the American Chemical Society, Год журнала: 2024, Номер 146(34), С. 24085 - 24093

Опубликована: Авг. 19, 2024

Stabilization of biologically relevant structural motifs has been a long-standing challenge. Here we show that atropisomeric dominant rotors can stabilize rare 3

Язык: Английский

Процитировано

0
Graphical Abstract: Angew. Chem. Int. Ed. 50/2023 DOI Open Access
Zhonglong Zhao, Jiangwei Zhang, Qin Wang

и другие.

Angewandte Chemie International Edition, Год журнала: 2023, Номер 62(50)

Опубликована: Дек. 6, 2023

An s-block potassium

Язык: Английский

Процитировано

0