Journal of the American Chemical Society,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 19, 2025
Mechanoluminescence
(ML)
materials
with
phosphorescent
characteristics
hold
significant
potential
for
applications
in
pressure
sensing
and
material
damage
inspection.
However,
currently
reported
mechanophosphorescence
(MP)
suffer
from
low
luminescence
efficiency
insufficient
brightness.
Herein,
we
report
a
piezoelectric
material,
p-BPM,
an
exceptionally
high
phosphorescence
of
61.4%,
which
is
the
highest
value
among
pure
organic
MP
materials.
Benefiting
its
excellent
ML
performance,
have
developed
display
device
using
crystals
that
allow
clear
observation
written
letter
paths
(letters
M
L),
promising
prospects
pressure-sensitive
display.
Amazingly,
also
observed
produce
bright
ultrasound
induced
medium
at
ultrasonic
operating
frequency
(40
kHz).
The
composite
films
crystal
poly(butylene
adipate-co-terephthalate)
(PBAT)
polymer
exhibit
tensile
strength
while
maintaining
effective
MP.
show
good
energy
harvesting
properties
maximum
open-circuit
voltage
0.47
V
short-circuit
current
0.046
μA,
demonstrating
promise
precise
sonic
location.
This
work
will
facilitate
development
highly
efficient
materials,
expanding
stress-monitoring,
imaging,
marine
robotics.
Chemical Science,
Год журнала:
2024,
Номер
15(12), С. 4222 - 4237
Опубликована: Янв. 1, 2024
In
this
perspective,
the
progress
in
ion-regulated
organic
RTP
materials
and
described
roles
of
ions,
including
ion–π
interactions,
electrostatic
coordinate
have
been
summarized.
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 10, 2025
Abstract
X‐ray
induced
photodynamic
therapy
(X‐PDT)
leverages
penetrating
to
generate
singlet
oxygen
(
1
O
2
)
for
treating
deep‐seated
tumors.
However,
conventional
X‐PDT
typically
relies
on
heavy
metal
inorganic
scintillators
and
organic
photosensitizers
produce
,
which
presents
challenges
related
toxicity
energy
conversion
efficiency.
In
this
study,
highly
biocompatible
phosphorescent
nanoscintillators
based
hydrogen‐bonded
frameworks
(HOF)
are
designed
engineered,
termed
BPT‐HOF@PEG,
enhance
in
hepatocellular
carcinoma
(HCC)
treatment.
BPT‐HOF@PEG
functions
simultaneously
as
both
scintillator
photosensitizer,
effectively
absorbing
transferring
abundant
.
Both
vitro
vivo
investigations
demonstrate
that
internalized
efficiently
produces
significant
quantities
of
upon
irradiation.
Additionally,
exposure
directly
inflicts
DNA
damage,
the
synergistic
effects
these
mechanisms
result
pronounced
cell
death
substantial
tumor
growth
inhibition,
with
a
inhibition
rate
up
90.4%
assessments.
RNA
sequencing
analyses
reveal
induces
apoptosis
Hepa1‐6
cells
while
inhibiting
proliferation,
culminating
death.
Therefore,
work
highlights
considerable
potential
efficient
HOF
nanoscintillators‐based
promising
therapeutic
approach
HCC,
providing
effective
alternative
negligible
patients
unresectable
ABSTRACT
Hepatectomy
is
a
critical
treatment
for
liver
cancer,
but
achieving
complete
tumor
removal
remains
challenging.
The
development
of
tumor‐targeting
probes
capable
accurately
identifying
locations
and
providing
real‐time
intraoperative
navigation
significant
clinical
importance.
We
synthesize
tumor‐targeted
probe
by
conjugating
fibroblast
activation
protein
inhibitor
(FAPI)
with
near‐infrared
organic
room
temperature
phosphorescence
(RTP)
material.
then
analyze
its
surgical
performance
in
the
cancer
model
imaging
fresh
patient‐derived
samples.
In
vivo
validation
reveals
that
exhibits
optimal
intensity
within
48
h
(8.53
×
10
5
p
s
−1
cm
−2
sr
)
an
average
signal‐to‐noise
ratio
16.
could
effectively
identify
FAP‐positive
samples
from
patients.
successful
application
phosphorescence‐guided
surgery
suggests
RTP
holds
translational
value
serve
as
auxiliary
tool
cancer.
Nature Communications,
Год журнала:
2024,
Номер
15(1)
Опубликована: Авг. 22, 2024
Sustainable
photoactivated
room
temperature
phosphorescent
materials
exhibit
great
potential
but
are
difficult
to
obtain.
Here,
we
develop
by
covalently
attaching
lignin
polylactic
acid,
where
and
acid
the
chromophore
matrix,
respectively.
Initially
phosphorescence
of
is
quenched
residual
O2.
However,
switched
on
when
oxygen
consumed
triplet
excitons
under
continuous
UV
light
irradiation.
As
such,
lifetime
increases
from
3.0
ms
221.1
after
20
s
activation.
Interestingly,
again
being
kept
an
atmosphere
air
for
2
h
in
absence
irradiation
due
diffusion
into
materials.
Using
these
properties,
as-developed
material
successfully
used
as
a
smart
anti-counterfeiting
logo
medicine
bottle
information
recording.
Convenient
sustainable
(RTP)
wide
ranging
applications
Here
authors
RTP
acid.
Angewandte Chemie,
Год журнала:
2024,
Номер
136(26)
Опубликована: Апрель 19, 2024
Abstract
Fluorescence
sensing
is
crucial
to
studying
biological
processes
and
diagnosing
diseases,
especially
in
the
second
near‐infrared
(NIR‐II)
window
with
reduced
background
signals.
However,
it's
still
a
great
challenge
construct
“off‐on”
sensors
when
wavelength
extends
into
NIR‐II
region
obtain
higher
imaging
contrast,
mainly
due
difficult
synthesis
of
spectral
overlapped
quencher.
Here,
we
present
new
fluorescence
quenching
strategy,
which
utilizes
steric
hindrance
quencher
(SHQ)
tune
molecular
packing
state
fluorophores
suppress
emission
signal.
Density
functional
theory
(DFT)
calculations
further
reveal
that
large
SHQs
can
competitively
pack
prevent
their
self‐aggregation.
Based
on
this
mechanism,
novel
activatable
method
achieved
via
bio‐analyte
responsive
invalidation
SHQ,
namely
Steric
Hindrance
Invalidation
geNerated
Emission
(SHINE)
strategy.
As
proof
concept,
ClO
−
‐sensitive
SHQ
lead
bright
signal
release
epileptic
mouse
hippocampus
under
skull
high
photon
scattering
brain
tissue,
providing
real‐time
visualization
generation
process
living
mice.
Chemical Communications,
Год журнала:
2024,
Номер
60(70), С. 9328 - 9339
Опубликована: Янв. 1, 2024
This
article
summarizes
the
potential
of
TPP
salts
in
tuning
RTP
properties
and
their
applications
multi-level
information
encryption,
high-level
anticounterfeiting
tags,
X-ray
scintillators.
National Science Review,
Год журнала:
2024,
Номер
12(2)
Опубликована: Окт. 29, 2024
ABSTRACT
Organic
red/near-infrared
(NIR)
room-temperature
phosphorescence
(RTP)
holds
significant
potential
for
autofluorescence-free
bioimaging
and
biosensing
due
to
its
prolonged
persistent
luminescence
exceptional
penetrability.
However,
achieving
activatable
red/NIR
organic
RTP
probes
with
tunable
emission
in
aqueous
solution
remains
a
formidable
challenge.
Here
we
report
on
intensity
lifetime
amplification.
These
consist
of
supramolecular
assemblies
comprising
macrocyclic
cucurbit[8]uril
amine-containing
alkyl-bridged
pyridiniums,
exhibiting
viscosity-activatable
enhanced
quantum
yield
(≤20%)
lifetime.
Notably,
by
utilizing
this
probe,
successfully
achieve
two-photon
imaging
lysosomal
viscosity
millisecond-scale
time-resolved
cell
imaging.
Moreover,
intravital
using
an
probe
enables
the
monitoring
variations
inflammatory
mice,
demonstrating
significantly
improved
signal-to-background
ratio
compared
fluorescence
This
platform
facilitates
versatile
high-resolution
vivo
tracking
specific
biomarkers
physiological
events.
Chemical Science,
Год журнала:
2024,
Номер
15(13), С. 4881 - 4889
Опубликована: Янв. 1, 2024
Simultaneously
enhancing
the
quantum
yields
and
luminescence
lifetimes
of
organic
persistent
room
temperature
phosphorescence
(RTP)
molecules
is
a
priority
in
photonic
area,
but
it
remains
formidable
challenge.
Here,
an
effective
strategy
was
proposed
to
improve
both
efficiencies
emission
decay
times
for
phosphorescent
triphenylphosphine
salts.
This
approach
involves
integrating
electron
donor
unit
into
salt
Angewandte Chemie International Edition,
Год журнала:
2024,
Номер
63(26)
Опубликована: Апрель 19, 2024
Fluorescence
sensing
is
crucial
to
studying
biological
processes
and
diagnosing
diseases,
especially
in
the
second
near-infrared
(NIR-II)
window
with
reduced
background
signals.
However,
it's
still
a
great
challenge
construct
"off-on"
sensors
when
wavelength
extends
into
NIR-II
region
obtain
higher
imaging
contrast,
mainly
due
difficult
synthesis
of
spectral
overlapped
quencher.
Here,
we
present
new
fluorescence
quenching
strategy,
which
utilizes
steric
hindrance
quencher
(SHQ)
tune
molecular
packing
state
fluorophores
suppress
emission
signal.
Density
functional
theory
(DFT)
calculations
further
reveal
that
large
SHQs
can
competitively
pack
prevent
their
self-aggregation.
Based
on
this
mechanism,
novel
activatable
method
achieved
via
bio-analyte
responsive
invalidation
SHQ,
namely
Steric
Hindrance
Invalidation
geNerated
Emission
(SHINE)
strategy.
As
proof
concept,
ClO
