Photo-mediated radical relay oximinosulfonamidation of alkenes with N-nitrosamines triggered by DABSO

Green Chemistry, Год журнала: 2024, Номер 26(13), С. 7849 - 7856

Опубликована: Янв. 1, 2024

N -Nitrosamines represent a class of bifunctional nitrogen-radical precursors, but their application potential remains largely unexplored.

Язык: Английский

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Photoinduced Vicinal Sulfamoyloximation of Alkenes: Harnessing Bifunctional Nitrosamines via a Rapid Radical Trapping Strategy

Organic Letters, Год журнала: 2024, Номер 26(29), С. 6253 - 6258

Опубликована: Июль 17, 2024

We developed a photoinduced method for vicinal sulfamoyloximation of alkenes using

Язык: Английский

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Emerging progress: photochemical transformation of nitroso compounds

Science China Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Июль 17, 2024

Язык: Английский

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Dearomative 1,4-Difunctionalization of Non-Activated Arenes Enabled by Boryl Radical-Mediated Halogen-Atom Transfer

ACS Catalysis, Год журнала: 2025, Номер unknown, С. 1294 - 1304

Опубликована: Янв. 7, 2025

Given the widespread presence of spirocyclic scaffolds in natural products and pharmacologically relevant synthetic compounds, development efficient methodologies for their construction holds great importance medicinal chemistry pharmaceutical research. In this study, a general photochemical dearomative spirocyclization nonactivated arenes has been established. The key to method lies ability amine-borane radicals activate aryl bromides iodides via halogen-atom transfer, thereby allowing conversion halides into corresponding subsequent chemodivergent transformations. remarkable compatibility versatility 1,4-difunctionalization is showed by rapid assembly structurally diverse 1,4-cyclohexadiene-based spirocycles incorporating oxindole, indoline, or dihydrobenzofuran subunits. Moreover, potential utility protocol exemplified formal total synthesis vasopressin V2 receptor antagonist Satavaptan.

Язык: Английский

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Chemodivergent dearomatization of benzene-linked O-oxime esters via EnT-induced radical cross-coupling

Chemical Science, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Radical-mediated dearomatization strategies offer a blueprint for building value-added and synthetically valuable three-dimensional skeletons from readily available aromatic starting materials.

Язык: Английский

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C(sp³)—H Bond Oximinylation

Acta Chimica Sinica, Год журнала: 2025, Номер 83(4), С. 390 - 390

Опубликована: Янв. 1, 2025

Язык: Английский

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N-Nitrosamide chemistry: Synthesis and applications in organic transformations

Tetrahedron Letters, Год журнала: 2024, Номер 145, С. 155154 - 155154

Опубликована: Июнь 21, 2024

Язык: Английский

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