Green Chemistry, Год журнала: 2023, Номер 25(7), С. 2681 - 2689
Опубликована: Янв. 1, 2023
Herein, a straightforward route for dual α,β-C(sp 3 )–H functionalized cyclic N -aryl amines using combination of electrocatalysis and iron catalysis is disclosed, setting the stage challenging multiple site selective C–H functionalization.
Язык: Английский
Angewandte Chemie International Edition, Год журнала: 2022, Номер 62(3)
Опубликована: Ноя. 16, 2022
Herein, a direct, metal-free, and site-selective electrochemical C-H carboxylation of arenes by reductive activation using CO2 as the economic abundant carboxylic source was reported. The electrocarboxylation carried out in an operationally simple manner with high chemo- regioselectivity, setting stage for challenging unactivated (hetero)arenes. robust nature strategy reflected broad scope substrates excellent atom economy unique selectivity. Notably, direct selective various worked well this approach, including electron-deficient naphthalenes, pyridines, phenyl derivatives, substituted quinolines. method benefits from being externally catalyst-free, metal-free base-free, which makes it extremely attractive potential applications.
Язык: Английский
Процитировано
68
Green Chemistry, Год журнала: 2023, Номер 25(8), С. 3095 - 3102
Опубликована: Янв. 1, 2023
A regiodivergent electrochemical defluorocarboxylation of gem -difluorocyclopropanes is realized, providing access to branched and linear carboxylated monofluorinated alkenes.
Язык: Английский
Процитировано
30
Journal of the American Chemical Society, Год журнала: 2024, Номер 146(21), С. 14864 - 14874
Опубликована: Май 16, 2024
The exploitation of carbon dioxide (CO2) as a sustainable, plentiful, and harmless C1 source for the catalytic synthesis enantioenriched carboxylic acids has long been acknowledged pivotal task in synthetic chemistry. Herein, we present current-driven nickel-catalyzed reductive carboxylation reaction with CO2 fixation, facilitating formation C(sp3)–C(sp2) bonds by circumventing handling moisture-sensitive organometallic reagents. This electroreductive protocol serves practical platform, paving way propargylic (up to 98% enantiomeric excess) from racemic carbonates CO2. efficacy this transformation is exemplified its successful utilization asymmetric total (S)-arundic acid, (R)-PIA, (S)-chizhine D, (S)-cochlearin G, (S,S)-alexidine, thereby underscoring potential electrosynthesis achieve complex molecular architectures sustainably.
Язык: Английский
Процитировано
18
Angewandte Chemie International Edition, Год журнала: 2024, Номер 63(22)
Опубликована: Март 26, 2024
Abstract Upgrading CO 2 to value‐added chiral molecules via catalytic asymmetric C−C bond formation is a highly important yet challenging task. Although great progress on the of centrally carboxylic acids has been achieved, construction axially with never reported date. Herein, we report first synthesis , which enabled by nickel‐catalyzed dynamic kinetic reductive carboxylation racemic aza‐biaryl triflates. A variety acids, are valuable but difficult obtain catalysis, generated in an enantioconvergent version. This new methodology features good functional group tolerance, easy scale‐up, facile transformation and avoids cumbersome steps, handling organometallic reagents using stoichiometric materials. Mechanistic investigations indicate process induced nickel catalysis.
Язык: Английский
Процитировано
16
Arabian Journal of Chemistry, Год журнала: 2024, Номер 17(8), С. 105822 - 105822
Опубликована: Май 24, 2024
Owing to the environmental and energy problems nowadays, one of enormous challenges is expanding clean, renewable reduce destructive ecological effects chemical industries. Compared with other traditional processes, electrochemical method has some benefits, such as being selective, causing minor waste, working under mild conditions no external oxidizing or reducing reagents, making this approach more economical eco-friendly. Electrochemistry represents a powerful tool within synthetic organic chemistry. The development part chemistry intends performance reactions employing electrons, including adding removing electrons. Using electric current reagent advantages, simplicity reactions, accessibility materials, replacing toxic applying an eco-friendly environment. During last decades, there been much effort decrease usage fossil fuels, electricity emerged common source. conversion into leads new paths, naturally safe environmentally friendly. Developing electrochemistry approaches for performing high-performance essential reaction green strategy because utilization instead stoichiometric oxidants reductants. Due its helpful friendly ability produce reactive intermediates, advanced considerably in oxidative hydrogen evolution coupling sacrificial anode electroreduction. New developments focus on developing electrolytic catalysts,photoelectrocatalysis, bioelectrosynthesis, optimizing electrode paired electrolysis, artificial intelligence-assisted electrosynthesis. Thus, daily significant number construction projects possibilities electrochemistry. Electrochemical methods constructing compounds have tolerated renewal past decades. Organic wealthy background synthesis. We hope review helps attract attention from researchers by using processes laboratory industrial centers, which pollution create In review, organohalides synthesizing various products summarized discussed since 2000.
Язык: Английский
Процитировано
13
Science China Chemistry, Год журнала: 2024, Номер 67(10), С. 3366 - 3372
Опубликована: Авг. 16, 2024
Язык: Английский
Процитировано
11
Organic Letters, Год журнала: 2024, Номер 26(15), С. 3241 - 3246
Опубликована: Апрель 5, 2024
Herein, we report an electrochemical protocol for the dicarboxylation of aryl alkynes using CO2. With a graphite rod as cathode and Al sacrificial anode, series valuable butenedioic acids are obtained in moderate to excellent yields with E/Z ratio up 50:1. This method features high E-selectivity, step atom economy, easy scalability, nice substrate scope, which renders it appealing promising applications organic synthesis materials chemistry.
Язык: Английский
Процитировано
10
Chemical Society Reviews, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
This review highlights organo-mediators that enable electrochemical reactions via outer-sphere electron transfer (ET), offering advantages such as availability, tunability, and simplified post-processing compared to direct electrolysis.
Язык: Английский
Процитировано
1
Chemical Communications, Год журнала: 2022, Номер 58(98), С. 13539 - 13555
Опубликована: Янв. 1, 2022
This Minireview highlights recent advancements within five years (since 2017) in electrocarboxylation with CO 2 under mild conditions.
Язык: Английский
Процитировано
35
Industrial Chemistry and Materials, Год журнала: 2023, Номер 1(1), С. 93 - 105
Опубликована: Янв. 1, 2023
The recent progress in multicomponent catalyst design for CO 2 /N /NO x electroreduction is summarized from three models.
Язык: Английский
Процитировано
18