Extending the natural adaptive capacity of coral holobionts

Nature Reviews Earth & Environment, Год журнала: 2021, Номер 2(11), С. 747 - 762

Опубликована: Окт. 12, 2021

Язык: Английский

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Coral microbiome manipulation elicits metabolic and genetic restructuring to mitigate heat stress and evade mortality

Science Advances, Год журнала: 2021, Номер 7(33)

Опубликована: Авг. 13, 2021

Probiotics mitigate post-heat stress disorder, preventing coral mortality.

Язык: Английский

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Harnessing the microbiome to prevent global biodiversity loss

Nature Microbiology, Год журнала: 2022, Номер 7(11), С. 1726 - 1735

Опубликована: Июль 21, 2022

Язык: Английский

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Coral Probiotics: Premise, Promise, Prospects

Annual Review of Animal Biosciences, Год журнала: 2020, Номер 9(1), С. 265 - 288

Опубликована: Дек. 15, 2020

The use of Beneficial Microorganisms for Corals (BMCs) has been proposed recently as a tool the improvement coral health, with knowledge in this research topic advancing rapidly. BMCs are defined consortia microorganisms that contribute to health through mechanisms include (a) promoting nutrition and growth, (b) mitigating stress impacts toxic compounds, (c) deterring pathogens, (d) benefiting early life-stage development. Here, we review current BMC approach outline studies have proven its potential increase resilience stress. We revisit expand list putative beneficial associated corals their mechanismsthat facilitate improved host performance. Further, discuss caveats bottlenecks affecting efficacy close by focusing on next steps application at larger scales can improve outcomes reefs globally.

Язык: Английский

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Towards enhancing coral heat tolerance: a “microbiome transplantation” treatment using inoculations of homogenized coral tissues

Microbiome, Год журнала: 2021, Номер 9(1)

Опубликована: Май 6, 2021

Microbiome manipulation could enhance heat tolerance and help corals survive the pressures of ocean warming. We conducted coral microbiome transplantation (CMT) experiments using reef-building corals, Pocillopora Porites, investigated whether this technique can benefit resistance while modifying bacterial microbiome. Initially, heat-tolerant donors were identified in wild. then used fresh homogenates made from donor tissues to inoculate conspecific, heat-susceptible recipients documented their bleaching responses microbiomes by 16S rRNA gene metabarcoding.Recipients both species bleached at lower rates compared control group when exposed short-term stress (34 °C). One hundred twelve (Pocillopora sp.) sixteen (Porites donor-specific indicating transmission bacteria. The amplicon sequence variants majority these transmitted bacteria belonged known, putatively symbiotic taxa linked observed beneficial effect on response. dynamics our support notion that community evenness dominance one or few species, rather than host-species identity, drivers for stability a holobiont context.Our results suggest likely favor uptake putative symbionts, recommending include taxonomic groups future probiotics screening efforts. Our study suggests scenario where symbionts might have been more efficient supporting resist native present group. These findings urgently call further experimental investigation mechanisms action underlying CMT field-based long-term studies testing persistence effect. Video abstract.

Язык: Английский

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Coral holobiont cues prime Endozoicomonas for a symbiotic lifestyle

The ISME Journal, Год журнала: 2022, Номер 16(8), С. 1883 - 1895

Опубликована: Апрель 20, 2022

Abstract Endozoicomonas are prevalent, abundant bacterial associates of marine animals, including corals. Their role in holobiont health and functioning, however, remains poorly understood. To identify potential interactions within the coral holobiont, we characterized novel isolate marisrubri sp. nov. 6c assessed its transcriptomic proteomic response to tissue extracts native host, Red Sea Acropora humilis. We show that stimulated differential expression genes putatively involved symbiosis establishment via modulation host immune by E. 6c, such as for flagellar assembly, ankyrins, ephrins, serpins. Proteome analyses revealed upregulated vitamin B1 B6 biosynthesis glycolytic processes cues. Our results suggest priming a symbiotic lifestyle involves immunity exchange essential metabolites with other members. Consequently, may play an important nutrient cycling therefore contribute health, acclimatization, adaptation.

Язык: Английский

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The coral microbiome: towards an understanding of the molecular mechanisms of coral–microbiota interactions

FEMS Microbiology Reviews, Год журнала: 2023, Номер 47(2)

Опубликована: Март 1, 2023

Corals live in a complex, multipartite symbiosis with diverse microbes across kingdoms, some of which are implicated vital functions, such as those related to resilience against climate change. However, knowledge gaps and technical challenges limit our understanding the nature functional significance complex symbiotic relationships within corals. Here, we provide an overview complexity coral microbiome focusing on taxonomic diversity functions well-studied cryptic microbes. Mining literature indicate that while corals collectively harbour third all marine bacterial phyla, known symbionts antagonists represent minute fraction this these taxa cluster into select genera, suggesting selective evolutionary mechanisms enabled bacteria gain niche holobiont. Recent advances research aimed at leveraging manipulation increase coral's fitness help mitigate heat stress-related mortality discussed. Then, insights potential through microbiota can communicate modify host responses examined by describing recognition patterns, microbially derived epigenome effector proteins gene regulation. Finally, power omics tools used study highlighted emphasis integrated host-microbiota multiomics framework understand underlying during change-driven dysbiosis.

Язык: Английский

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The coral microbiome in sickness, in health and in a changing world

Nature Reviews Microbiology, Год журнала: 2024, Номер 22(8), С. 460 - 475

Опубликована: Март 4, 2024

Язык: Английский

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Triggers, cascades, and endpoints: connecting the dots of coral bleaching mechanisms

Biological reviews/Biological reviews of the Cambridge Philosophical Society, Год журнала: 2024, Номер 99(3), С. 715 - 752

Опубликована: Янв. 12, 2024

ABSTRACT The intracellular coral–dinoflagellate symbiosis is the engine that underpins success of coral reefs, one most diverse ecosystems on planet. However, breakdown and loss microalgal symbiont (i.e. bleaching) due to environmental changes are resulting in rapid degradation reefs globally. There an urgent need understand cellular physiology bleaching at mechanistic level help develop solutions mitigate reef crisis. Here, unprecedented scope, we present novel models integrate putative mechanisms within a common framework according triggers (initiators bleaching, e.g. heat, cold, light stress, hypoxia, hyposalinity), cascades (cellular pathways, photoinhibition, unfolded protein response, nitric oxide), endpoints (mechanisms loss, apoptosis, necrosis, exocytosis/vomocytosis). supported by direct evidence from cnidarian systems, indirectly through comparative evolutionary analyses non‐cnidarian systems. With this approach, new have been established between initiated different triggers. In particular, provide insights into poorly understood connections highlight role mechanism i.e. ‘symbiolysosomal digestion’, which symbiophagy. This review also increases approachability for specialists non‐specialists mapping vast landscape atlas comprehensible detailed models. We then discuss major knowledge gaps how future research may improve understanding cascade pathways (endpoints).

Язык: Английский

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Probiotics reshape the coral microbiome in situ without detectable off-target effects in the surrounding environment

Communications Biology, Год журнала: 2024, Номер 7(1)

Опубликована: Апрель 9, 2024

Beneficial microorganisms for corals (BMCs), or probiotics, can enhance coral resilience against stressors in laboratory trials. However, the ability of probiotics to restructure microbiome situ is yet be determined. As a first step elucidate this, we inoculated putative probiotic bacteria (pBMCs) on healthy colonies Pocillopora verrucosa Red Sea, three times per week, during 3 months. pBMCs significantly influenced microbiome, while surrounding seawater and sediment remained unchanged. The genera Halomonas, Pseudoalteromonas, Bacillus were enriched probiotic-treated corals. Furthermore, treatment also correlated with an increase other beneficial groups (e.g., Ruegeria Limosilactobacillus), decrease potential pathogens, such as Vibrio. all (treated non-treated) throughout experiment, could not track health improvements protection stress. Our data indicate that healthy, therefore stable, microbiomes restructured situ, although repeated continuous inoculations may required these cases. Further, our study provides supporting evidence that, at studied scale, have no detectable off-target effects near

Язык: Английский

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