Cascading of engineered bioenergy plants and fungi sustainable for low-cost bioethanol and high-value biomaterials under green-like biomass processing

Renewable and Sustainable Energy Reviews, Год журнала: 2020, Номер 137, С. 110586 - 110586

Опубликована: Дек. 15, 2020

Язык: Английский

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Addressing challenges in production of cellulases for biomass hydrolysis: Targeted interventions into the genetics of cellulase producing fungi

Bioresource Technology, Год журнала: 2021, Номер 329, С. 124746 - 124746

Опубликована: Янв. 29, 2021

Язык: Английский

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Recent advances in substrate-enzyme interactions facilitating efficient biodegradation of lignocellulosic biomass: A review

International Biodeterioration & Biodegradation, Год журнала: 2023, Номер 180, С. 105594 - 105594

Опубликована: Март 27, 2023

Язык: Английский

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From induction to secretion: a complicated route for cellulase production in Trichoderma reesei

Bioresources and Bioprocessing, Год журнала: 2021, Номер 8(1)

Опубликована: Окт. 22, 2021

Abstract The filamentous fungus Trichoderma reesei has been widely used for cellulase production that extensive applications in green and sustainable development. Increasing costs depletion of fossil fuels provoke the demand hyper-cellulase this cellulolytic fungus. To better manipulate T. enhanced to lower cost large-scale fermentation, it is wise have a comprehensive understanding crucial factors complicated biological network could provide new perspectives further exploration modification. In review, we summarize recent progress give an overview cellular process , including carbon source-dependent induction, transcriptional regulation network, efficient protein assembly trafficking. Among that, key involved were emphasized, shedding light on potential engineering.

Язык: Английский

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Recent progress in key lignocellulosic enzymes: Enzyme discovery, molecular modifications, production, and enzymatic biomass saccharification

Bioresource Technology, Год журнала: 2022, Номер 363, С. 127986 - 127986

Опубликована: Сен. 17, 2022

Язык: Английский

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Factors regulating cellulolytic gene expression in filamentous fungi: an overview

Microbial Cell Factories, Год журнала: 2022, Номер 21(1)

Опубликована: Март 22, 2022

Abstract The growing demand for biofuels such as bioethanol has led to the need identifying alternative feedstock instead of conventional substrates like molasses, etc. Lignocellulosic biomass is a relatively inexpensive that available in abundance, however, its conversion involves multistep process with different unit operations size reduction, pretreatment, saccharification, fermentation, distillation, saccharification or enzymatic hydrolysis cellulose glucose complex family enzymes called cellulases are usually fungal origin. Cellulose requires synergistic action several classes enzymes, and achieving optimum secretion these simultaneously remains challenge. expression controlled by an intricate network transcription factors sugar transporters. Several genetic engineering efforts have been undertaken modulate cellulolytic genes, well their regulators. This review, therefore, focuses on molecular mechanism effect hemicellulases.

Язык: Английский

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Promoter regulation and genetic engineering strategies for enhanced cellulase expression in Trichoderma reesei

Microbiological Research, Год журнала: 2022, Номер 259, С. 127011 - 127011

Опубликована: Март 21, 2022

Язык: Английский

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Diversity of Cellulase-Producing Filamentous Fungi From Tibet and Transcriptomic Analysis of a Superior Cellulase Producer Trichoderma harzianum LZ117

Frontiers in Microbiology, Год журнала: 2020, Номер 11

Опубликована: Июль 14, 2020

Filamentous fungi are widely used for producing cellulolytic enzymes to degrade lignocellulosic biomass. Microbial resources from Tibet have received great attention due the unique geographic and climatic conditions in Qinghai-Tibet Plateau. However, studies on cellulase fungal strains originated remain very limited, so far no been focused regulation of production specific thereof. Here, filamentous were isolated soil, plant, other environments Tibet, cellulase-producing further investigated. A total 88 identified, screening revealed that 16 affiliated with genera Penicillium, Trichoderma, Aspergillus, Talaromyces exhibited varying activities. Among these strains, T. harzianum isolate LZ117 is most potent producer. Comparative transcriptome analysis using control strain K223452 cultured cellulose indicated an intensive modulation gene transcription related protein synthesis quality control. Furthermore, xyr1 which encodes global transcriptional activator expression was significantly up-regulated. Transcription cre1 predicted repressors controlling decreased LZ117, may contribute enhancing formation primary cellulases. To our knowledge, this first report landscape at early enzyme stage comprehensively described, detailed transporters, regulatory proteins as well processing presented. Our study contributes increasing catalog publicly available data harzianum, provides useful clues unraveling biotechnological potential species biorefinery.

Язык: Английский

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Significance of glycans in cellulolytic enzymes for lignocellulosic biorefinery – A review

Bioresource Technology, Год журнала: 2023, Номер 379, С. 128992 - 128992

Опубликована: Апрель 1, 2023

Язык: Английский

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Promoting lignocellulosic biorefinery by machine learning: progress, perspectives and challenges

Bioresource Technology, Год журнала: 2025, Номер unknown, С. 132434 - 132434

Опубликована: Март 1, 2025

Язык: Английский

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